Cognitive Impairment and Obstructive Sleep Apnea

Otero, Liliana; Figueredo, María del Carmen; Riveros-Rivera, Alain; Hidalgo, Patricia

doi:10.5772/intechopen.82756

Cited by 7 publications

(10 citation statements)

References 88 publications

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“…Apnea is defined as a reduction in respiratory amplitude of > 80% for 10 s or longer during overnight polysomnography (Ayalon et al, 2010;Harper et al, 2013;Kumar et al, 2014;Lutsey et al, 2016). Cognitive impairment is fairly common in untreated moderate-to-severe COSA, with particular deficits in attention, specifically vigilance, acquisition of new memories, visuospatial abilities, and executive functions (Otero et al, 2019). These deficits frequently co-occur with mood disorders.…”

Section: Intermittent Hypoxiamentioning

confidence: 99%

Potential for Cognitive Communication Impairment in COVID-19 Survivors: A Call to Action for Speech-Language Pathologists

Ramage

2020

Am J Speech Lang Pathol

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Purpose Severe acute respiratory syndrome coronavirus 2 is the virus resulting in COVID-19 infections in nearly 4.3 million Americans with COVID-19 in the United States as of July 29, 2020, with nearly 150,000 deaths and hundreds of thousands of survivors ( https://www.coronavirus.jhu.edu/map.html ). This tutorial reviews (a) what has been reported about neurological insults in cases of COVID-19 infection, (b) what is known from similar conditions in other disorders, and (c) how that combined information can inform clinical decision making. Method PubMed and the Cochrane Central Register of Controlled Trials were searched for COVID-19 or other coronavirus infections, cognitive impairment observed following critical care, and disorders for which intermittent or chronic hypoxia is characteristic. These were combined with searches relating to cognition, brain, and communication. All searches were conducted between April 8 and May 23, 2020. Meta-analyses and randomized clinical trials addressing other critical illnesses were also included to extend findings to potential cognitive communication outcomes following COVID-19. Results COVID-19 infection results in a combination of (a) respiratory infection with mechanical ventilation secondary to inadequate oxygenation, (b) inflammatory system reactivity, and (c) increased blood clotting factors. These affect central nervous system function incurring long-term cognitive communication impairment in a proportion of survivors. Diagnostic and intervention approaches for such impairments are discussed. Conclusions The existing literature on cognitive sequela of COVID-19 infection is small to date, but much can be learned from similar viral infections and disorders. Although COVID-19 is novel, the speech-language pathology approaches to evaluation and intervention of other populations of critical care patients are applicable. However, speech-language pathologists have not routinely been involved in these patients' acute care. As such, this is a call to action to speech-language pathologists to address the unprecedented numbers of patients who will need their services early in the disease process and throughout recovery.

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Section: Intermittent Hypoxiamentioning

confidence: 99%

Potential for Cognitive Communication Impairment in COVID-19 Survivors: A Call to Action for Speech-Language Pathologists

Ramage

2020

Am J Speech Lang Pathol

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“…Previous studies showed that children with OSA display several issues in physical health [ 12 ], development [ 14 ], and comprehensive cognitive functions [ 15 – 17 , 19 , 22 – 24 ]. Shpirer et al [ 38 ] showed that hypoxemia correlated with attentional dysfunction in children with OSA.…”

Section: Discussionmentioning

confidence: 99%

“…The complications of OSA in children include physiological and physical complications including impaired cardiac function (pulmonary arterial hypertension, heart dilation, chronic cardiac dysfunction, and increased in right heart afterload) [ 12 , 13 ], impaired growth and development [ 14 ], and failure to thrive [ 15 ]. In addition to physical complications, OSA has detrimental effects on behavior and cognition [ 16 , 17 ], development [ 14 ], emotional state [ 18 , 19 ], quality of life [ 18 , 20 , 21 ], attention ability [ 19 , 22 ], and cognitive function [ 19 , 23 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of adenotonsillectomy on the growth, development, and comprehensive cognitive abilities of children with obstructive sleep apnea: a prospective single-arm study

Shan¹,

Wang²,

Yang

et al. 2022

BMC Pediatr

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Background Previous studies did not comprehensively examine the effect of adenotonsillectomy on growth and development, emotional state, quality of life, attention ability, and cognitive dysfunction in children with obstructive sleep apnea (OSA). This study aimed to explore the improvement effects of adenotonsillectomy on the growth, development, quality of life, and attention ability in children with OSA. Methods This prospective single-arm study involved children with OSA admitted at The No. 980 Hospital, Joint Logistics Support Force, PLA, China (02/2017–02/2018). The Myklebust Pupil Rating Scale (PRS), Inventory of Subjective Life Quality (ISLQ), Zung Self-rating Anxiety Scale (SAS), Conners Parent Symptom Questionnaire (PSQ), and Continuous Performance Task (CPT) were examined before and at 6 months after adenotonsillectomy. Results Forty-nine patients were enrolled. They all completed the 6-month follow-up. The body mass index increased after surgery (from 18.8 ± 4.9 to 19.3 ± 4.3 kg/m2, P = 0.008). The total PRS score increased 6 months after surgery (from 73.8 ± 12.7 to 84.6 ± 10.3, P < 0.001). All aspects of the ISLQ, except anxiety experience and physical emotion, were improved at 6 months after adenotonsillectomy (all P < 0.01). The SAS score also decreased from 20.1 ± 10.0 to 12.8 ± 6.6 (P < 0.001). All six dimensions of the PSQ, as assessed by the legal guardians, decreased after adenotonsillectomy (all P < 0.01). The proportions of children with auditory and/or visual sustained attention abnormalities decreased after surgery. Conclusions After adenotonsillectomy, the PRS, ISLQ, and PSQ improved, and anxiety and auditory/visual sustained attention abnormalities decreased, suggesting positive impacts on the growth, development, quality of life, and comprehensive cognitive abilities of children with OSA.

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“… 30 , 31 Several pathological changes accompany OSA and increase the risk of cognitive dysfunctions such as intermittent hypoxia, disturbed sleep, systemic inflammation, increased oxidative stress, comorbidities, and daytime sleepiness. 32 …”

Section: Discussionmentioning

confidence: 99%

Determining the prevalence of symptoms and risk of obstructive sleep apnoea among old Saudis

Aljawadi

Khoja

BaHammam

et al. 2021

Journal of Taibah University Medical Sciences

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Objectives This study aimed to determine the prevalence of symptoms and risk of obstructive sleep apnoea (OSA) and to identify the risk factors associated with OSA among old Saudis. Methods In this population-based survey, we administered the Saudi National Survey for Elderly Health to old Saudis between 2006 and 2007. Symptoms of OSA and its associated risk factors were determined using the Berlin questionnaire. A multivariable logistic regression analysis was used to determine key factors associated with the risk of OSA. Results Out of 2946 participants, 1544 (52.4%) were at high risk of OSA, with women having a higher risk than men (60.8% vs. 44.2%, respectively; p -value <0.001). Obesity was higher among women than men (40.5% vs. 24.8%, respectively; p -value <0.001). Almost 56% of the participants reported snoring as a risk factor, but there was no statistical difference between women and men (57.3% vs. 53.5%, respectively; p -value = 0.317). The factors identified as independent predictors of a high risk of OSA were the female gender (OR 1.732, 95% CI [1.375–2.182]), living in rural areas (OR 1.384, 95% CI [1.094–1.750]), severe cognitive impairment (OR 2.709, 95% CI [1.350–5.436]), depression (OR: 1.432 95%CI [1.147–1.789]), and antidepressants usage (OR 2.959, 95% CI [1.402–6.244]). Conclusion This study reported a 52.4% prevalence of a high risk of OSA. Women were more likely to be at high risk of OSA than men. In addition to the female gender, depression, antidepressant usage, severe cognitive impairment, and living in rural areas were main predictors of OSA.

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Cognitive Impairment and Obstructive Sleep Apnea

Cited by 7 publications

References 88 publications

Potential for Cognitive Communication Impairment in COVID-19 Survivors: A Call to Action for Speech-Language Pathologists

Potential for Cognitive Communication Impairment in COVID-19 Survivors: A Call to Action for Speech-Language Pathologists

Effect of adenotonsillectomy on the growth, development, and comprehensive cognitive abilities of children with obstructive sleep apnea: a prospective single-arm study

Determining the prevalence of symptoms and risk of obstructive sleep apnoea among old Saudis

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