In this paper, simplified digital content generation using single-shot depth estimation for full-color holographic printing system is proposed. Firstly, digital content generation is analyzed completely before the hardware system of holographic printing is run to provide a high-quality three-dimensional (3D) scene without degrading information of the original 3D object. Here, the single-shot depth estimation method is applied, and 3D information is acquired from the estimated highquality depth data and a given single 2D image. Then the array of sub-holograms (hogels) is generated directly by implementing fully analyzed computation considering chromatic aberration for full-color printing. Finally, the generated hogels are recorded into holographic material sequentially via effectual time-controlled exposure under synchronized control with three electrical shutters for RGB laser beam illuminations to obtain full-color 3D reconstruction. Numerical simulation and optical reconstructions are implemented successfully.