Colorectal Cancer Screening with CT Colonography, Colonoscopy, and Double-Contrast Barium Enema Examination: Prospective Assessment of Patient Perceptions and Preferences

Gluecker, Thomas M.; Johnson, C. Daniel; Harmsen, William S.; Offord, Kenneth P.; Harris, Ann; Wilson, Lynn A.; Ahlquist, David A.

doi:10.1148/radiol.2272020293

Cited by 274 publications

(137 citation statements)

References 16 publications

Supporting

Mentioning

128

Contrasting

Unclassified

Order By: Relevance

“…Data from large studies on screening cohorts have suggested that CTC and conventional colonoscopy have similar sensitivity for polyps ≥6-mm in diameter [8,9]. Moreover, patients generally prefer CTC instead of barium enema examination or colonoscopy [10][11][12][13]. However, concerns were raised about recommending CTC as routine screening tool because of potential harm [14,15].…”

Section: Introductionmentioning

confidence: 99%

Adverse events of computed tomography colonography: An Italian National Survey

Iafrate¹,

Iussich²,

Correale³

et al. 2013

Digestive and Liver Disease

View full text Add to dashboard Cite

a b s t r a c tAim: To retrospectively study the frequency and magnitude of complications associated with computed tomography (CT) colonography in clinical practice. Methods: A questionnaire on complications of CT colonography was sent to Italian public radiology departments identified as practicing CT colonography with a reasonable level of training. The frequency of complications and possible risk factors were retrospectively determined. Responses were collated and row frequencies determined. A multivariate analysis of the factors causing adverse events was also performed. Results: 40,121 examinations were performed in13 centers during the study period. No deaths were reported. Bowel perforations occurred in 0.02% (7 exams). All perforations were asymptomatic and occurred in patients undergoing manual insufflation. Five perforations (71%) occurred in procedures performed following a recent colonoscopy. There was no significant difference between perforations associated with rectal balloon (0.017%) and those that were not (0.02%). Complications related to vasovagal reaction (either with or without spasmolytic) occurred in 0.16% (63 exams). All vasovagal reactions resolved in less than 3 h, without any sequelae. Conclusions: Perforation rate at CT colonography in Italy is comparable with elsewhere in the world, occurring regardless of the experience of radiology centers. Although the risk is very small, it may not be negligible when compared with the risk of diagnostic colonoscopy.

show abstract

Section: Introductionmentioning

confidence: 99%

Adverse events of computed tomography colonography: An Italian National Survey

Iafrate¹,

Iussich²,

Correale³

et al. 2013

Digestive and Liver Disease

View full text Add to dashboard Cite

show abstract

“…However, it remains to be demonstrated if the advantages conferred by CO2 are sufficiently significant to improve patient acceptance of endoscopic procedures and cost-effectiveness (by reducing loss from normal activities after endoscopy). These two criteria, namely patient acceptance and cost-effectiveness, are of paramount importance for colorectal cancer screening as computed tomography (CT) colonography has been shown to be superior to colonoscopy for both of them [20,21] . Incidentally, one of the three CO2 insufflators that are available for endoscopy was developed initially for gut distension during CT colonography, and radiologists use it increasingly often for reasons of safety and patient comfort (CO2 is used in about half of CT colonographies) [22] .…”

Section: Discussionmentioning

confidence: 99%

Carbon dioxide for gut distension during digestive endoscopy: Technique and practice survey

Janssens¹,

Devière²,

Eisendrath³

et al. 2009

WJG

View full text Add to dashboard Cite

AIM:To assess the adoption of Carbon dioxide (CO2) insufflation by endoscopists from various European countries, and its determinants. M E T H O D S :A s u r v e y w a s d i s t r i b u t e d t o 5 8 0 endoscopists attending a live course on digestive endoscopy. RESULTS:The response rate was 24.5%. Fewer than half the respondents (66/142, 46.5%) were aware of the fact that room air can be replaced by CO2 for gut distension during endoscopy, and 4.2% of respondents were actually using CO2 as the insufflation agent. Endoscopists aware of the possibility of CO2 insufflation mentioned technical difficulties in implementing the system and the absence of significant advantages of CO2 in comparison with room air as barriers to adoption in daily practice (84% and 49% of answers, respectively; two answers were permitted for this item). CONCLUSION:Based on this survey, adoption of CO2 insufflation during endoscopy seems to remain relatively exceptional. A majority of endoscopists were not aware of this possibility, while others were not aware of recent technical developments that facilitate CO2 implementation in an endoscopy suite.

show abstract

“…Although the use of laxative ftCTC cases may provide excellent conditions for the application of automated imageprocessing methods, the requirement of laxative bowel cleansing is also considered to be one of the major barriers for patient adherence to colorectal cancer screening guidelines (Gluecker et al (2003); Beebe et al (2007)). Efforts to minimize this burden are under investigation and include, for example, structured low-fiber diets and complete elimination of the laxative dose (Lefere et al (2002); Zalis et al (2003); Iannaccone et al (2004)).…”

Section: Discussionmentioning

confidence: 99%

Adaptive correction of the pseudo-enhancement of CT attenuation for fecal-tagging CT colonography

Näppi

Yoshida

2008

Medical Image Analysis

View full text Add to dashboard Cite

In fecal-tagging CT colonography (ftCTC), orally administered positive-contrast tagging agents are used for opacifying residual bowel materials to facilitate reliable detection of colorectal lesions. However, tagging agents that have high radio-density tend artificially to elevate the observed CT attenuation of nearby materials to that of tagged materials on a standard Hounsfield unit (HU) scale due to the pseudo-enhancement effect. We developed an image-based adaptive density-correction (ADC) method for minimizing pseudo-enhancement in ftCTC data. After the correction, we can confidently assume that soft-tissue materials and air are represented by CT attenuations on the standard HU scale, whereas higher CT attenuations indicate tagged materials. The ADC method was optimized for ftCTC by use of an anthropomorphic phantom filled partially with 300 HU, 600 HU, and 900 HU tagging concentrations. The effect of ADC on ftCTC was assessed visually and quantitatively by comparison of the accuracy of computer-aided detection (CAD) without and with the use of the ADC method in two different types of clinical ftCTC databases: 20 laxative ftCTC cases with 24 polyps, and 23 reduced-preparation ftCTC cases with 28 polyps. Visual evaluation suggested that ADC minimizes the observed pseudo-enhancement in phantoms and clinical cases. Quantitative evaluation suggested that ADC yields a significant improvement in the CAD accuracy in clinical databases. The results indicate that ADC is a useful pre-processing method for automated image processing applications in CTC.

show abstract

Colorectal Cancer Screening with CT Colonography, Colonoscopy, and Double-Contrast Barium Enema Examination: Prospective Assessment of Patient Perceptions and Preferences

Abstract: Patients undergoing colorectal cancer screening prefer CT colonography to both colonoscopy and DCBE. The majority of patients experience discomfort and inconvenience with cathartic bowel preparation.

Cited by 274 publications

References 16 publications

Adverse events of computed tomography colonography: An Italian National Survey

Adverse events of computed tomography colonography: An Italian National Survey

Carbon dioxide for gut distension during digestive endoscopy: Technique and practice survey

Adaptive correction of the pseudo-enhancement of CT attenuation for fecal-tagging CT colonography

Contact Info

Product

Resources

About