Colorectal polyps and carcinoma in Southern Iran

Abstract

A study was made of the prevalence of colorectal polyps (excluding juvenile polyps, familial polyposis coli and villous adenomas) and the minimum frequency of colorectal carcinoma in Southern Iran. A total of 801 large intestines from necropsies performed on individuals 20 years or older was examined with or without magnifying lens for presence of polyps. Our prevalence rate was then compared with those reported on postmortem material from the USA, Australia, South Africa (Bantus), Colombia, and Hawaii (Japanese immigrants). Our surgical pathology files were reviewed for colorectal polyps over a 22-year period (1952-1973). Colorectal carcinomas diagnosed in the Department of Pathology were reviewed over 11 years (1963-1973) and the minimum frequency rates compared with corresponding age- and sex-specific incidence rates from Connecticut, USA. The data indicate 1) a very low prevalence rate for colorectal polyps as well as carcinoma in our region and 2) a rather striking predominance of right-sided colonic carcinoma.

Pathology of Colorectal Polyps, A Study from South of Iran

“…It is very important to know the distribution of colorectal polyps in every country, because it may affect the efficacy of screening modalities and also the prevalence of adenomas that roughly equivalent to the risk of colorectal malignancies (4, 5). There are very few studies from Iran and Middle East regarding to the distribution of different types of colorectal polyps (1,3). Therefore in this study we tried to evaluate the frequency of nonmalignant colorectal polyps concerning their type, age, gender and location.…”

Occurrence of Colorectal Adenomas in Younger Adults: An Epidemiologic Necropsy Study

“…Other data concerning the prevalence of adenomas in younger adults are scarce but comes from two sources-autopsy studies and colonoscopy screening for colorectal cancer. The largest autopsy series are those of Haghighi et al (9) (411 Iranian necropsies between ages 20-49) and Restrepo et al (10) (332 Columbian cases <44 of age). These investigators found the prevalence of colorectal adenomas to be 1.2% and 2.4%, respectively.…”

Clinical predictors of colorectal polyps and carcinoma in a low prevalence region: Results of a colonoscopy based study

“…Variation in the incidence of colorectal neoplasia has been observed in populations and even in cities of one country. In 1997 autopsy studies from Iran have reported the incidence of colorectal polyps to be 1.6% [11] . Recent…”