Combination of levulinic acid and sodium dodecyl sulfate on inactivation of foodborne microorganisms: A review

Doyle, Michael P.; Chen, Dong

doi:10.1080/10408398.2019.1650249

Cited by 24 publications

(12 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While not assessed in the current study, the concentration of LA (1 M) or SDS (0.04 M) that reached a MIC 90 should be safe for individuals that would potentially utilize MoWa to decontaminate hospital surfaces, and others that might be present in the hospital facility. The safety of LA and SDS for humans has been widely assessed, and therefore, those two compounds were designated by the US Food and Drug Administration (FDA) as GRAS given they can be directly added to food as a flavoring substance (LA), or as a multipurpose additive (SDS) ( Zhou et al., 2019 ; Administration FFaD, 2021 ). Furthermore, the investigated LD 50 of SDS is 977 mg/kg, thereby it will require 233 M of SDS to affect an individual weighing 70 kg.…”

Section: Discussionmentioning

confidence: 99%

“…Levulinic acid plus SDS-based intervention approaches for reducing contamination with shiga toxin-producing E. coli (STEC) have also proven effective in reducing the bacterial density, although in those studies, the temperature has been a factor for the reduction of bacterial viability with the greatest reduction obtained at temperatures >8°C ( Ortega et al., 2011 ; Zhou et al., 2019 ). This was not a factor in our study as our in vitro test was conducted at 35°C, and the ambient temperature, when assessed using the surface-contaminated model, was ~20°C.…”

Section: Discussionmentioning

confidence: 99%

“…A solution made with levulinic acid [1 M (LA)] and sodium dodecyl sulfate [0.5 M (SDS, also known as lauryl sulfate)] has proven effective to sanitize produce contaminated with Salmonella spp., Listeria spp., and enterohemorrhagic Escherichia coli (EHEC), and to inactivate influenza A virus and surrogates for human norovirus ( Zhao et al., 2009 ; Cannon et al., 2012 ; Aydin et al., 2013 ; Zhou et al., 2020 ). This LA/SDS (1 ;M/0.04 M) solution reduced the density of Salmonella species by >7 logs and the density of shiga toxin-producing E. coli strains by >5 logs within minutes ( Zhao et al., 2009 ; Zhao et al., 2010 ; Zhao et al., 2014 ).…”

Section: Introductionmentioning

confidence: 99%

“…Both LA and SDS are g enerally r ecognized a s s afe (GRAS) ingredients for food use according to the USFDA (21 CFR 172.822 and 172.515) ( Administration FFaD, 2021 ). Furthermore, these two compounds are approved as food additives, including as a flavoring substance in the case of LA, or as a multipurpose additive for SDS ( Zhou et al., 2019 ; Administration FFaD, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

MoWa: A Disinfectant for Hospital Surfaces Contaminated With Methicillin-Resistant Staphylococcus aureus (MRSA) and Other Nosocomial Pathogens

Gregory

Ellis

Valeriani

et al. 2021

Front. Cell. Infect. Microbiol.

View full text Add to dashboard Cite

IntroductionStaphylococcus aureus strains, including methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA), are a main cause of nosocomial infection in the world. The majority of nosocomial S. aureus-infection are traced back to a source of contaminated surfaces including surgery tables. We assessed the efficacy of a mixture of levulinic acid (LA) and sodium dodecyl sulfate (SDS), hereafter called MoWa, to eradicate nosocomial pathogens from contaminated surfaces.Methods and ResultsA dose response study demonstrated that MoWa killed 24 h planktonic cultures of S. aureus strains starting at a concentration of (LA) 8.2/(SDS) 0.3 mM while 24 h preformed biofilms were eradicated with 32/1.3 mM. A time course study further showed that attached MRSA bacteria were eradicated within 4 h of incubation with 65/2 mM MoWa. Staphylococci were killed as confirmed by bacterial counts, and fluorescence micrographs that were stained with the live/dead bacterial assay. We then simulated contamination of hospital surfaces by inoculating bacteria on a surface prone to contamination. Once dried, contaminated surfaces were sprayed with MoWa or mock-treated, and treated contaminated surfaces were swabbed and bacteria counted. While bacteria in the mock-treated samples grew at a density of ~104 cfu/cm2, those treated for ~1 min with MoWa (1.0/0.04 M) had been eradicated below limit of detection. A similar eradication efficacy was obtained when surfaces were contaminated with other nosocomial pathogens, such as Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, or Staphylococcus epidermidis.ConclusionsMoWa kills planktonic and biofilms made by MRSA and MSSA strains and showed great efficacy to disinfect MRSA-, and MSSA-contaminated, surfaces and surfaces contaminated with other important nosocomial pathogens.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

MoWa: A Disinfectant for Hospital Surfaces Contaminated With Methicillin-Resistant Staphylococcus aureus (MRSA) and Other Nosocomial Pathogens

Gregory

Ellis

Valeriani

et al. 2021

Front. Cell. Infect. Microbiol.

View full text Add to dashboard Cite

show abstract

“…LVA is generated by degradation of cellulosic bio-stocks and is inexpensive. Both LVA and LA are thought to inhibit food-borne bacterial outgrowth ( € Ozogul and Hamed 2018;Zhou et al 2020). The combination of LVA and SDS as a disinfectant has drawn considerable research interest in the past few years.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of SDS and GRAS liquid disinfectants for mitigation of hepatitis A virus contamination of berries

Kingsley

Annous

2021

J Appl Microbiol

View full text Add to dashboard Cite

show abstract

Management strategies emphasizing advanced food processing approaches to mitigate food borne zoonotic pathogens in food system

2022

View full text Add to dashboard Cite

Foodborne zoonoses are the most neglected discipline due to a lack of awareness of potential health hazards, standardized detection methods, and identification of infectious host reservoirs. Food is the major carriage vehicle for the transmission of zoonotic pathogens and many outbreaks globally. Resilient surveillance and holistic intervention of effective mitigation strategies at both preharvest (bacteriophages, probiotics, vaccination, micronutrients, breeding, culling), postharvest (advanced food processing, biofilm removal, and disinfectant), retailer and consumer levels can reduce or prevent pathogens and cross-contamination. Rapid tracking of contamination sources and identification of the route of infection should be implemented using analytical techniques for targeted detection of causative organisms and microbiological risk assessment. An overview elaborating various farm-to-fork pathogenic mitigation strategies at different stages of the food chain is presented. However, special emphasis is placed on the application of advanced novel food processing and preservation techniques, such as high-pressure processing, pulsed light, ultrasound, ultraviolet light, ozone treatment, irradiation and other hurdle technologies for pathogen reduction and food quality assurance. This review will provide an overview of the overall scenario regarding foodborne pathogen-human health interactions and the possible prevention measures that would be helpful for producers, manufacturers, retailers, and consumers for the safer and sustainable development of food products.

show abstract

Combination of levulinic acid and sodium dodecyl sulfate on inactivation of foodborne microorganisms: A review

Cited by 24 publications

References 59 publications

MoWa: A Disinfectant for Hospital Surfaces Contaminated With Methicillin-Resistant Staphylococcus aureus (MRSA) and Other Nosocomial Pathogens

MoWa: A Disinfectant for Hospital Surfaces Contaminated With Methicillin-Resistant Staphylococcus aureus (MRSA) and Other Nosocomial Pathogens

Evaluation of SDS and GRAS liquid disinfectants for mitigation of hepatitis A virus contamination of berries

Management strategies emphasizing advanced food processing approaches to mitigate food borne zoonotic pathogens in food system

Contact Info

Product

Resources

About