Combined Mastopexy and Augmentation with Autologous Fat Grafting: First Results with Lipopexy

Abstract

Background: The treatment of breast ptosis and gland hypoplasia in a single surgery is a challenging procedure and the result is less predictable. In this surgery, the complications mainly concern the prosthesis, such as implant deflation, capsular contracture, palpability, or malposition. We, therefore, propose a different and new technique that avoids breast prosthesis, combining mastopexy and autologous augmentation with fat grafts. Methods: Combined mastopexy and autologous fat graft augmentation (lipopexy) was performed in women affected by breast ptosis and asymmetric breast or hypomastia. The breast lift technique was determined due to the ptosis level. The process of fat grafting was executed according to the PureGraft and, in some cases, to GID System, to Celution System or Carraway’s techniques. Results: Thirty-four patients affected by breast ptosis and hypomastia underwent lipopexy from January 2010 to May 2017. The mean volume of adipose tissue injected for each breast was 225.98 ml. After surgery, the patients were followed for an average of 22.8 months. A mild ptosis relapse with partial fat absorption was observed in 4 cases (11.76%) and the presence of oily cysts was diagnosed in 2 patients (5.88%). One severe complication was recorded (hematoma drainage). All the patients healed uneventfully in 2 weeks. Conclusions: This technique allows the surgeon to distribute the desired fat volume along the breasts, avoids implants, and displayed stable results. This treatment has been demonstrated not to interfere with follow-up breast imaging. We, therefore, consider lipopexy a valuable and safe alternative to mastopexy and mild to moderate breast volume augmentation.

Comparative technical analysis of lipoaspirate mechanical processing devices

“…In one work (Brzezienski & Jarrell, 2016), surgeons indifferently used the GID700 and Puregraft devices, and no comparison of clinical results is made. The identified clinical results refer to multiple fields of application: 14 papers refer to breast reconstruction (Brzezienski & Jarrell, 2016;Chiu, Fracol, Feld, Qiu, & Kim, 2019;De Fazio & Cingozoglu, 2020;Economides & Song, 2018;Gabriel et al, 2017;Lee et al, 2011;Losken et al, 2011;Mestak et al, 2014;Mestak, Mestak, Bohac, Edriss, & Sukop, 2013;Mestak & Zimovjanová, 2012;Ruan et al, 2019;Russe et al, 2015;Sforza, Andjelkov, Zaccheddu, Husein, & Atkinson, 2016;Wang et al, 2012), 5 to osteoarthritis (4 of the knee and 1 of the hip) (Barfod & Blønd, 2019;Dall'Oca et al, 2019;Jones et al, 2018;Panchal, Malanga, & Sheinkop, 2018;Schiavone Panni et al, 2019), 3 to complex anal fistula (Laureti et al, 2020;Naldini, Sturiale, Fabiani, Giani, & Menconi, 2018;Topal, Eray, Rencüzo gulları, Yalav, & Alabaz, 2019), whereas 8 studies concern different pathologies (Casarotti, Chiodera, & Tremolada, 2018;Cestaro, De Rosa, Massa, Amato, & Gentile, 2015;Cherian, Malanga, Hogaboom, Pollack, & Dyson-Hudson, 2019;Hirahara, Andersen, & Panero, 2017;Kuka et al, 2020;Lonardi et al, 2019;Saibene, Pipolo, Lorusso, Portaleone, & Felisati, 2015;Zuin et al, 2019). The interesting fact is that all the aforementioned devices are mainly used for breast reconstructions, exc...…”

Stem Cells in Autologous Microfragmented Adipose Tissue: Current Perspectives in Osteoarthritis Disease

“…In addition, grafts from PureGraft displayed larger particles (>1000 μm) and were able to operate a “dialysis” of the adipose tissue without resorting to other, more destructive methods such as centrifugation [ 95 ]. The main use of these technologies is in the field of fat grafting for breast volumes [ 96 ]. The most studied and commonly used system in clinical practice is the LIPOGEMS device.…”