Common Carotid Artery Diameter, Blood Flow Velocity and Wave Intensity Responses at Rest and during Exercise in Young Healthy Humans: A Reproducibility Study

Pomella, Nicola; Wilhelm, Eurico Nestor; Kolyva, Christina; González‐Alonso, José; Rakobowchuk, Mark; Khir, Ashraf W.

doi:10.1016/j.ultrasmedbio.2016.12.018

Cited by 30 publications

(23 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One distinct advantage of the lnDU-loop method, however, is that it provides a means for determining c using measurements, which are direct and local to a specific arterial segment. It is worth noting that we have previously demonstrated the reproducibility of the lnDU-loop method (12), and the results agree with those in Ref. 13.…”

Section: Comparisonssupporting

confidence: 90%

Reply to Mynard et al.

Pomella

Wilhelm

Kolyva

et al. 2018

American Journal of Physiology-Heart and Circulatory Physiology

View full text Add to dashboard Cite

Section: Comparisonssupporting

confidence: 90%

Reply to Mynard et al.

Pomella

Wilhelm

Kolyva

et al. 2018

American Journal of Physiology-Heart and Circulatory Physiology

View full text Add to dashboard Cite

“…The Womersley number α 1 = 3.585 is slightly below reported physiological values 4.4-5. 24,37 The real part of the leading frequency of the wave speed c R1 = 643.519 cm/s is on the lower bound of the 6.4-10.2 m/s reported for human common carotid artery 38 . The leading frequency spatial wavelength is λ 1 = 707.871 cm, consistent with a long-wave approximation given the radius of the vessel.…”

Section: Validity Of Linearity and Long-wave Approximation Assumptionsmentioning

confidence: 91%

Verification of the coupled‐momentum method with Womersley's Deformable Wall analytical solution

Filonova

Arthurs

Vignon-Clémentel

et al. 2019

Numer Methods Biomed Eng

View full text Add to dashboard Cite

In this paper, we perform a verification study of the Coupled‐Momentum Method (CMM), a 3D fluid‐structure interaction (FSI) model which uses a thin linear elastic membrane and linear kinematics to describe the mechanical behavior of the vessel wall. The verification of this model is done using Womersley's deformable wall analytical solution for pulsatile flow in a semi‐infinite cylindrical vessel. This solution is, under certain premises, the analytical solution of the CMM and can thus be used for model verification. For the numerical solution, we employ an impedance boundary condition to define a reflection‐free outflow boundary condition and thus mimic the physics of the analytical solution, which is defined on a semi‐infinite domain. We first provide a rigorous derivation of Womersley's deformable wall theory via scale analysis. We then illustrate different characteristics of the analytical solution such as space‐time wave periodicity and attenuation. Finally, we present the verification tests comparing the CMM with Womersley's theory.

show abstract

“…Statistical significance was assumed for P < 0.05. The reproducibility of the aforementioned hemodynamic and wave intensity parameters in young, healthy individuals has been established in a previous study ( 28 ). All parameters were reproducible both at rest and during exercise.…”

Section: Methodsmentioning

confidence: 99%

Noninvasive assessment of the common carotid artery hemodynamics with increasing exercise work rate using wave intensity analysis

Pomella

Wilhelm

Kolyva

et al. 2018

American Journal of Physiology-Heart and Circulatory Physiology

View full text Add to dashboard Cite

Noninvasively determined local wave speed (c) and wave intensity (WI) parameters provide insights into arterial stiffness and cardiac-vascular interactions in response to physiological perturbations. However, the effects of incremental exercise and subsequent recovery on c and WI have not been fully established. We examined the changes in c and WI parameters in the common carotid artery (CCA) during exercise and recovery in eight young, healthy male athletes. Ultrasound measurements of CCA diameter and blood flow velocity were acquired at rest, during five stages of incremental exercise (up to 70% maximum work rate), and throughout 1 h of recovery, and noninvasive WI analysis [diameter-velocity (DU) approach] was performed. During exercise, c increased (+136%), showing increased stiffness with work rate. All peak and area of forward compression, backward compression, and forward expansion waves increased during exercise (+452%, +700%, and +900%, respectively). However, WI reflection indexes and CCA resistance did not significantly change from rest to exercise. Furthermore, wave speed and the magnitude of all waves returned to baseline within 5 min of recovery, suggesting that the effects of exercise in the investigated parameters of young, healthy individuals were transient. In conclusion, incremental exercise was associated with an increase in local CCA stiffness and increases in all wave parameters, indicative of enhanced ventricular contractility and improved late-systolic blood flow deceleration.NEW & NOTEWORTHY We examined hemodynamics of the common carotid artery using noninvasive application of wave intensity analysis during exercise and recovery. The hemodynamic adjustments to exercise were associated with increases in local common carotid artery stiffness and all waves’ parameters, with the latter indicating enhanced ventricular contractility and improved late systolic blood flow deceleration.

show abstract

Common Carotid Artery Diameter, Blood Flow Velocity and Wave Intensity Responses at Rest and during Exercise in Young Healthy Humans: A Reproducibility Study

Cited by 30 publications

References 40 publications

Reply to Mynard et al.

Reply to Mynard et al.

Verification of the coupled‐momentum method with Womersley's Deformable Wall analytical solution

Noninvasive assessment of the common carotid artery hemodynamics with increasing exercise work rate using wave intensity analysis

Contact Info

Product

Resources

About