Common characteristics of upper and lower airways in rhinitis and asthma: ARIA update, in collaboration with GA<sup>2</sup>LEN

Cruz, Álvaro Augusto; Popov, Todor A.; Pawankar, Ruby; Annesi‐Maesano, Isabella; Fokkens, Wytske J.; Kemp, James P.; Ohta, Ken; Price, David; Bousquet, Jean

doi:10.1111/j.1398-9995.2007.01551.x

Cited by 255 publications

(196 citation statements)

References 185 publications

(314 reference statements)

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“…(20) Studies have shown that rhinitis and asthma are interrelated, and that the appropriate treatment of allergic rhinitis improves asthma control, decreasing symptoms and reducing the risk of emergency room visits and hospitalizations. (21)(22)(23)(24)(25) Indeed, 35 children in the ProAR-FS with mild asthma (23.6% of the sample of children and adolescents) and persistent rhinitis, using exclusively nasal corticosteroid, were not hospitalized, and there was a decrease of 84.2% in the frequency of emergency room visits during monitoring in the ProAR-FS. Scientific evidence suggests that treatment of rhinitis with topical nasal corticosteroids prevents bronchial hyperresponsiveness associated with the exposure to allergens and can avoid the exacerbations of symptoms in patients with mild asthma.…”

Section: Resultsmentioning

confidence: 99%

Hospitalizações por asma: impacto de um programa de controle de asma e rinite alérgica em Feira de Santana (BA)

et al. 2009

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Objective: To evaluate the impact of the Programa de Controle da Asma e Rinite Alérgica em Feira de Santana (ProAR-FS, Program for the Control of Asthma and Allergic Rhinitis in Feira de Santana) on the frequency of hospitalizations for asthma in patients monitored at a referral center for one year. Methods: This was a historical control study involving 253 consecutive patients with asthma, ages ranging from 4 to 76 years. We compared the frequency of hospital admissions and visits to the emergency room (ER) in the 12 months prior to and after their admission to the ProAR-FS. During the program, patients received free treatment, including inhaled medications and education on asthma. Demographic and socioeconomic aspects were also assessed. Results: There was a significant reduction in the number of hospitalizations (465 vs. 21) and of visits to the ER (2,473 vs. 184) after their admission to ProAR-FS (p < 0.001 for both). Of the 253 patients who had been hospitalized and had had ER visits within the year prior to the admission to ProAR-FS, only 16 were hospitalized and 92 visited the ER during the follow-up year, representing a reduction of 94% and 64%, respectively. Conclusions: Implementing a referral center for the treatment of asthma and rhinitis in the Unified Health Care System, with the free distribution of inhaled corticosteroids and the support of an education program, is a highly effective strategy for the control of asthma.Keywords: Hospitalization; Asthma; Rhinitis; Health services; Public health. ResumoObjetivo: Avaliar o impacto do Programa de Controle da Asma e Rinite Alérgica em Feira de Santana (ProAR-FS) na frequência de hospitalizações por asma em pacientes acompanhados por um ano em um centro de referência. Métodos: Estudo de controle histórico de 253 pacientes com asma, entre 4 e 76 anos idade, e admitidos consecutivamente. Comparou-se a frequência de internações e de atendimentos em emergência nos doze meses anteriores e posteriores à sua inclusão no ProAR-FS. Durante o programa, os pacientes receberam atendimento gratuito, incluindo medicação inalatória e educação em asma. Os aspectos demográficos e socioeconômicos também foram avaliados. Resultados: Houve redução significativa no número de internações (463 vs. 21) e de atendimentos em emergência (2.473 vs. 184) após a matrícula no ProAR-FS (p < 0,001 para ambos). Dos 253 pacientes internados e atendidos na emergência no ano anterior à participação no ProAR-FS, apenas 16 foram novamente internados e 92 foram atendidos na emergência durante o ano de acompanhamento, correspondendo a uma redução de 94% e 64%, respectivamente. Conclusões: A implementação de um ambulatório de referência para o tratamento de asma e rinite no Sistema Público de Saúde, com o fornecimento de corticoide inalatório e o suporte de um programa de educação, é uma estratégia muito efetiva para o controle da asma.

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Section: Resultsmentioning

confidence: 99%

Hospitalizações por asma: impacto de um programa de controle de asma e rinite alérgica em Feira de Santana (BA)

et al. 2009

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“…rhinitis and asthma, has increased in past decades [23,24]. In most European countries grass pollen allergy is the first [23]/second [25] most prevalent respiratory allergy. Grass pollen allergy was recently associated with seasonal asthma exacerbations…”

Section: Pollen and Mould Allergymentioning

confidence: 99%

Climate change and respiratory diseases

D’Amato

Cecchi²,

D’Amato³

et al. 2014

Eur Respir Rev

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@ERSpublications Climate change represents a threat to respiratory health by acting on respiratory diseases or their risk factors http://ow.ly/v6JElChanges in climate constitute a reality that, according to recent projections, is going to worsen in the coming years. Climate change represents a massive threat to respiratory health: 1) by directly promoting or aggravating respiratory diseases; or 2) by increasing exposure to risk factors for respiratory diseases. Climate change increases the amount of pollen and allergen produced by each plant, mould proliferation and the concentrations of outdoor ozone and particulate matter at ground level. The main diseases of concern are asthma, rhinosinusitis, chronic obstructive pulmonary disease (COPD) and respiratory tract infections. Groups at higher risk of climate change effects include individuals with pre-existing cardiopulmonary diseases or disadvantaged individuals. Adaptation and mitigation measures are strongly needed.It is now widely accepted that the earth's temperature is increasing, as confirmed by warming of the oceans, rising sea levels, glaciers melting, sea ice retreating in the Arctic and diminished snow cover in the Northern Hemisphere. Moreover, changes are also occurring in the amount, intensity, frequency and type of precipitation, as well as the increase of extreme weather events, such as heat waves, droughts, floods and hurricanes [1][2][3]. Most of the observed increase in globally averaged temperatures since the mid-20th century is probably due to the observed increase in anthropogenic greenhouse gas (namely carbon dioxide, methane and the nitrous oxides) concentrations [1]. Projections of future greenhouse gas emissions indicate a worsening of the situation with between a 1.1 and 6.4uC increase in the mean temperature by the end of the 21st century [1].Climate change represents a massive direct threat to respiratory health by promoting or aggravating respiratory diseases or indirectly by increasing exposure to risk factors for respiratory diseases [4]. Climate affects weather, air and water quality, local and national food supplies, economics and many other critical health determinants. Observational evidence indicates that regional changes in climate, particularly temperature increases, affect a diverse set of physical and biological systems in many parts of the world [1, 2], some of which are of concern for respiratory health. A rapid rise has been observed in the number of hot days, such as the 2003 heat wave where temperatures of o35uC were reached resulting in ,40 000 excess deaths across Europe, mostly for cardiopulmonary causes [5,6]. Sea levels have also started to rise as an effect of a regression of the polar ice packs. Both heat waves and melting ice have led to water deprivation in certain

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“…Allergic rhinitis is often associated with asthma and a global perspective is needed (46,47). In some studies, it has been found that NAR is also associated with asthma (7,14,48).…”

Section: Epidemiologic Studiesmentioning

confidence: 99%

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA²LEN paper

Bousquet

Fokkens

Burney

et al. 2008

Allergy

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Important research questions in allergy and related diseases: nonallergic rhinitis: a GA 2 LEN paper Nonallergic rhinitis (NAR) can be defined as a chronic nasal inflammation which is not caused by systemic IgE-dependent mechanisms. It is common and probably affects far more than 200 million people worldwide. Both children and adults are affected. However, its exact prevalence is unknown and its phenotypes need to be evaluated using appropriate methods to better understand its pathophysiology, diagnosis and management. It is important to differentiate between infectious rhinitis, allergic/NAR and chronic rhinosinusitis, as management differs for each of these cases. Characterization of the phenotype, mechanisms and management of NAR represents one of the major unmet needs in allergic and nonallergic diseases. Studies on children and adults are required in order to appreciate the prevalence, phenotype, severity and co-morbidities of NAR. These studies should compare allergic and NAR and consider different age group populations including elderly subjects. Mechanistic studies should be carried out to better understand the disease(s) and risk factors and to guide towards an improved diagnosis and therapy. These studies need to take the heterogeneity of NAR into account. It is likely that neuronal mechanisms, T cells, innate immunity and possibly auto-immune responses all play a role in NAR and may also contribute to the symptoms of allergic rhinitis.

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Common characteristics of upper and lower airways in rhinitis and asthma: ARIA update, in collaboration with GA²LEN

Cited by 255 publications

References 185 publications

Hospitalizações por asma: impacto de um programa de controle de asma e rinite alérgica em Feira de Santana (BA)

Hospitalizações por asma: impacto de um programa de controle de asma e rinite alérgica em Feira de Santana (BA)

Climate change and respiratory diseases

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA²LEN paper

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Common characteristics of upper and lower airways in rhinitis and asthma: ARIA update, in collaboration with GA2LEN

Cited by 255 publications

References 185 publications

Hospitalizações por asma: impacto de um programa de controle de asma e rinite alérgica em Feira de Santana (BA)

Hospitalizações por asma: impacto de um programa de controle de asma e rinite alérgica em Feira de Santana (BA)

Climate change and respiratory diseases

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper

Contact Info

Product

Resources

About

Common characteristics of upper and lower airways in rhinitis and asthma: ARIA update, in collaboration with GA²LEN

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA²LEN paper