Community-acquired lower urinary tract infections: Etiology, antimicrobial resistance, and treatment results in female patients

Erdem, İlknur; Ali, Rıdvan; Ardic, Enes; Omar, Senay Elbasan; Mutlu, Reyhan; Topkaya, Aynur Eren

doi:10.4103/jgid.jgid_86_17

Cited by 41 publications

(45 citation statements)

References 23 publications

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“…Other ESBL producing Enterobacteriaceae detected in Turkey include CTX-M/TEM/SHV/qnrA aac(6′)-ib Enterobacter spp. and VEB-1/qnrA1 Providencia stuartii (Nazik et al, 2009, 2011; Erdem et al, 2018). Interestingly, Agin et al (2011) reported an outbreak of Salmonella enterica serovar typhimurium producing SHV-12 and CTX-M-3 ESBLs.…”

Section: Distribution Of Multi-drug Resistant Organisms In Humansmentioning

confidence: 99%

Understanding the Epidemiology of Multi-Drug Resistant Gram-Negative Bacilli in the Middle East Using a One Health Approach

et al. 2019

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In the last decade, extended-spectrum cephalosporin and carbapenem resistant Gram-negative bacilli (GNB) have been extensively reported in the literature as being disseminated in humans but also in animals and the environment. These resistant organisms often cause treatment challenges due to their wide spectrum of antibiotic resistance. With the emergence of colistin resistance in animals and its subsequent detection in humans, the situation has worsened. Several studies reported the transmission of resistant organisms from animals to humans. Studies from the middle east highlight the spread of resistant organisms in hospitals and to a lesser extent in livestock and the environment. In view of the recent socio-economical conflicts that these countries are facing in addition to the constant population mobilization; we attempt in this review to highlight the gaps of the prevalence of resistance, antibiotic consumption reports, infection control measures and other risk factors contributing in particular to the spread of resistance in these countries. In hospitals, carbapenemases producers appear to be dominant. In contrast, extended spectrum beta lactamases (ESBL) and colistin resistance are becoming a serious problem in animals. This is mainly due to the continuous use of colistin in veterinary medicine even though it is now abandoned in the human sphere. In the environment, despite the small number of reports, ESBL and carbapenemases producers were both detected. This highlights the importance of the latter as a bridge between humans and animals in the transmission chain. In this review, we note that in the majority of the Middle Eastern area, little is known about the level of antibiotic consumption especially in the community and animal farms. Furthermore, some countries are currently facing issues with immigrants, poverty and poor living conditions which has been imposed by the civil war crisis. This all greatly facilitates the dissemination of resistance in all environments. In the one health concept, this work re-emphasizes the need to have global intervention measures to avoid dissemination of antibiotic resistance in humans, animals and the environment in Middle Eastern countries.

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Section: Distribution Of Multi-drug Resistant Organisms In Humansmentioning

confidence: 99%

Understanding the Epidemiology of Multi-Drug Resistant Gram-Negative Bacilli in the Middle East Using a One Health Approach

et al. 2019

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“…The microbial spectrum of UTIs mainly consists of Escherichia coli, and other uropathogens such as Staphylococcus saprophyticus, Enterococcus, Proteus sp., Pseudomonas aeruginosa, Candida albicans, and Klebsiella pneumonia are rarely isolated from UTIs [12]. Enterobacteriaceae is a diverse group of pathogens that accounts 80% of gram-negative bacterial isolates that cause various diseases in humans, including urinary tract infections [13].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Antibiogram of MDR E. coli Strains Isolated from UTI Patients—1-Year Retrospective Study at Nishtar Medical Hospital, Multan

Fatima

Rafiq

Iqbal

et al. 2020

SN Compr. Clin. Med.

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MDR uropathogens lead to high-level morbidity and mortality and pose a tremendous threat towards treatment failure and survival of UTI patients. This study was conducted to evaluate the demographic characteristics, antibiogram, and resistance pattern of Escherichia coli against antibiotics-a retrospective study at Nishtar Medical Hospital in Multan, from June 2016 to July 2017. A total of 150 clinical samples were collected and biochemically characterized by Berge's manual, and antimicrobial susceptibility testing was performed by using the Kirby-Bauer disc diffusion method and the results were interpreted according to Clinical and Laboratory Standards Institute standards. Data was analyzed by the XL-stat software. Results indicate that UTI was more prevalent in rural areas such as Alipur (28.6%) and Jalalpur (18%) and less common in urban areas like Muzaffargarh (2.66) and Multan (2%). A total of 150 patients were examined, of which 88 were females and 62 males in which more frequently found pathogens were E. coli (33%) and others Klebsiella pneumonia (18%), Proteus (10%), Staphylococcus saprophyticus (8.66%), Staphylococcus aureus (7.33%), Pseudomonas aeruginosa (6.66%), Enterobacter (6%), Candida (5.33%), and Citrobacter (4.66%). The antimicrobial susceptibility testing was carried out against E. coli strains that showed the highest overall resistance patterns of imipenem (IMI), Cip, Aug, Cfm, and CN, which were 80%, 72%, 68%, 60%, and 52%, respectively. MDR E. coli strains showed the highest resistance pattern towards IMI which put through alarming situation in Pakistan. Significant results showed that TZP, AK, and F were found sensitive in vitro against E. coli isolates of UTIs. Prevalence of MDR uropathogens near around Multan has been first time documented in this study with respect to possible risk factors associated with UTI. These alarming signs of MDR E. coli have been rarely addressed and warrant attention on urgent basis.

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“…[ 6 ] In it, they found E. coli to be the most common organism and 32% of them were extended-spectrum beta-lactamase (ESBL) producing. [ 6 ] In their study, fosfomycin and nitrofurantoin were found to be the drugs with least resistance and highest eradication rate. However, in the Norwegian study, nitrofurantoin resistance was quite high.…”

mentioning

confidence: 99%

State of the globe: Rising antimicrobial resistance of pathogens in urinary tract infection

Paul

2018

J Global Infect Dis

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Community-acquired lower urinary tract infections: Etiology, antimicrobial resistance, and treatment results in female patients

Cited by 41 publications

References 23 publications

Understanding the Epidemiology of Multi-Drug Resistant Gram-Negative Bacilli in the Middle East Using a One Health Approach

Understanding the Epidemiology of Multi-Drug Resistant Gram-Negative Bacilli in the Middle East Using a One Health Approach

Prevalence and Antibiogram of MDR E. coli Strains Isolated from UTI Patients—1-Year Retrospective Study at Nishtar Medical Hospital, Multan

State of the globe: Rising antimicrobial resistance of pathogens in urinary tract infection

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