Comparative distribution of somatostatin and thrittene bioactive peptides in the central nervous system of rat measured by radioimmunoassay

Fürjes, Gergely; Lelesz, Beáta; Tóth, Gábor; Arday, A.; Szilvássy, Zoltán; Varga, Angelika; Berényi, Ervin; Németh, József

doi:10.1007/s10967-016-5132-7

Cited by 4 publications

(2 citation statements)

References 38 publications

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“…In the central nervous system, most neurons contain bioactive peptides. 125 Neuropeptides have multiple physiological functions, which include regulating pain, learning, and memory. 126 Neuropeptides have a great relationship with the occurrence and development of Parkinson's disease, depression, and some mental diseases else.…”

Section: Neurodegenerative Diseasesmentioning

confidence: 99%

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Application of peptide biomarkers in life analysis based on liquid chromatography–mass spectrometry technology

Han

Cong

et al. 2022

BioFactors

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Biomedicine is developing rapidly in the 21st century. Among them, the qualitative and quantitative analysis of peptide biomarkers is of considerable importance for the diagnosis and therapy of diseases and the quality evaluation of drugs and food. The identification and quantitative analysis of peptides have been going on for decades. Traditionally, immunoassays or biological assays are generally used to quantify peptides in biological matrices. However, the selectivity and sensitivity of these methods cannot meet the requirements of the application. The separation and analysis technique of liquid chromatography-mass spectrometry (LC-MS) supplies a reliable alternative. In contrast to immunoassays, LC-MS methods are capable of providing the analytical prowess necessary to satisfy the demands of peptide biomarker research in the life sciences arena. This review article provides a historical account of the in-roads made by LC-MS technology for the detection of peptide biomarkers in the past 10 years, with the focus on the qualification/quantification developments and their applications.

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Section: Neurodegenerative Diseasesmentioning

confidence: 99%

“…Neuropeptides are endogenous active substances in the nervous system. In the central nervous system, most neurons contain bioactive peptides 125 . Neuropeptides have multiple physiological functions, which include regulating pain, learning, and memory 126 .…”

Section: Application Of Lc–ms In the Detection Of Peptide Biomarkersmentioning

confidence: 99%

Application of peptide biomarkers in life analysis based on liquid chromatography–mass spectrometry technology

Han

Cong

et al. 2022

BioFactors

View full text Add to dashboard Cite

show abstract

Development of an electrochemical sensor based on porous molecularly imprinted polymer via photopolymerization for detection of somatostatin in pharmaceuticals and human serum

Özkan

Çorman

Nemutlu

et al. 2022

Journal of Electroanalytical Chemistry

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An immunological determination of somatostatin in pharmaceutical by sandwich ELISA based on IgY and polyclonal antibody

Chen

Liang

et al. 2019

Microchemical Journal

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Comparative distribution of somatostatin and thrittene bioactive peptides in the central nervous system of rat measured by radioimmunoassay

Cited by 4 publications

References 38 publications

Application of peptide biomarkers in life analysis based on liquid chromatography–mass spectrometry technology

Application of peptide biomarkers in life analysis based on liquid chromatography–mass spectrometry technology

Development of an electrochemical sensor based on porous molecularly imprinted polymer via photopolymerization for detection of somatostatin in pharmaceuticals and human serum

An immunological determination of somatostatin in pharmaceutical by sandwich ELISA based on IgY and polyclonal antibody

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