Development of an electrochemical sensor based on porous molecularly imprinted polymer via photopolymerization for detection of somatostatin in pharmaceuticals and human serum

Özkan, Ece; Çorman, M. Emin; Nemutlu, Emirhan; Özkan, Síbel A.; Kır, Sedef

doi:10.1016/j.jelechem.2022.116554

Cited by 10 publications

(3 citation statements)

References 24 publications

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“…Electrochemical Sensors. MIPs for sensing were prepared using the PP method, as described by Ozkan et al 17 First, the prepolymer complex was prepared in distilled water by mixing 20 μL 1.0 mM AA and 20 μL 1.0 mM VEN in a 1:1 ratio (v/ v). HEMA (20 μL) and EGDMA (100 μL) were added to the AA/VEN complex.…”

Section: Preparation Of the Mip-and Nip-basedmentioning

confidence: 99%

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Molecularly Imprinted Electrochemical Sensor for the Ultrasensitive and Selective Detection of Venetoclax

Ozkan,

Bellur Atici,

Ozkan

2024

ACS Omega

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In this study, a new electropolymerized molecularly imprinted polymer (MIP) film was synthesized on a glassy carbon electrode (GCE) by a photopolymerization (PP) method using acrylamide (AA) as a functional monomer and venetoclax (VEN) as a template molecule. Optimization steps of the MIP film were performed using ferrocyanide/ferricyanide [Fe(CN) 6 ] 3−/4− as a redox probe. Removal and rebinding of the template molecule were investigated by differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS).

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Section: Preparation Of the Mip-and Nip-basedmentioning

confidence: 99%

“…23 The specificity of the MIP electrode was appraised by calculating imprinting factors (IF) for PP-AA@MIP-GCE and PP-AA@NIP-GCE. 17 The ΔI value for each molecule was divided by the value for VEN to determine the imprinting factor (IF). Relative IF (IF') value is defined as the ratio of IF values for MIP and NIP.…”

Section: Specificity Studiesmentioning

confidence: 99%

Molecularly Imprinted Electrochemical Sensor for the Ultrasensitive and Selective Detection of Venetoclax

Ozkan,

Bellur Atici,

Ozkan

2024

ACS Omega

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“…Characterization techniques such as SEM, Fourier-Transform Infrared spectroscopy (FTIR), and EIS were utilized for examining the P(HEMA-MAAsp)@MIP/GCE sensor. Under ideal conditions, the P(HEMA-MAAsp)@MIP/GCE sensor offered a femtomolar detection limit and limit of quantification (LOQ) of 0.584 fM [ 49 ].…”

Section: Determination Of Various Analytes Via Mipsmentioning

confidence: 99%

Picomolar or beyond Limit of Detection Using Molecularly Imprinted Polymer-Based Electrochemical Sensors: A Review

et al. 2022

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Over the last decades, molecularly imprinted polymers (MIPs) have emerged as selective synthetic receptors that have a selective binding site for specific analytes/target molecules. MIPs are synthetic analogues to the natural biological antigen–antibody system. Owing to the advantages they exhibit, such as high stability, simple synthetic procedure, and cost-effectiveness, MIPs have been widely used as receptors/sensors for the detection and monitoring of a variety of analytes. Moreover, integrating electrochemical sensors with MIPs offers a promising approach and demonstrates greater potential over traditional MIPs. In this review, we have compiled the methods and techniques for the production of MIP-based electrochemical sensors along with the applications of reported MIP sensors for a variety of analytes. A comprehensive in-depth analysis of recent trends reported on picomolar (pM/10−12 M)) and beyond picomolar concentration LOD (≥pM) achieved using MIPs sensors is reported. Finally, we discuss the challenges faced and put forward future perspectives along with our conclusion.

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A highly sensitive TiO2-based molecularly imprinted photoelectrochemical sensor with regulation of imprinted sites by Photo-deposition

Yan

Han

Hou

et al. 2023

Journal of Colloid and Interface Science

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Development of an electrochemical sensor based on porous molecularly imprinted polymer via photopolymerization for detection of somatostatin in pharmaceuticals and human serum

Cited by 10 publications

References 24 publications

Molecularly Imprinted Electrochemical Sensor for the Ultrasensitive and Selective Detection of Venetoclax

Molecularly Imprinted Electrochemical Sensor for the Ultrasensitive and Selective Detection of Venetoclax

Picomolar or beyond Limit of Detection Using Molecularly Imprinted Polymer-Based Electrochemical Sensors: A Review

A highly sensitive TiO2-based molecularly imprinted photoelectrochemical sensor with regulation of imprinted sites by Photo-deposition

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