Comparative study of axial and femoral bone mineral density and parameters of mandibular bone quality in patients receiving dental implants

Amorim, Marta; Takayama, Lilian; Jorgetti, Vanda; Pereira, Rosa Maria Rodrigues

doi:10.1007/s00198-006-0131-0

Cited by 28 publications

(13 citation statements)

References 31 publications

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“…Concerns have therefore been raised about the interrelationship between endosseous implant and osteoporosis, a condition associated with a decrease in bone quality and quantity . Although there is still no common consensus about the influence of osteoporosis on implant osseointegration, studies in patients seem to indicate that osteoporosis is not an absolute contraindication for dental implant; osseointegration in osteoporotic bone can be obtained although may be delayed …”

Section: Introductionmentioning

confidence: 99%

Effect of osteoporosis on fixation of osseointegrated implants in rats

Hua

et al. 2016

J Biomed Mater Res

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The effect of osteoporosis on implant osseointegration has been widely investigated, whereas osteoporosis may also newly occur in patient with previously osseointegrated implant. This study was designed to investigate the effect of osteoporosis on implant fixation in rats after successful osseointegration had been obtained. Seventy female Sprague-Dawley rats were included, and each animal received two titanium implants in the distal metaphysis of femur bilaterally. Eight weeks later, ten rats were sacrificed to confirm the establishment of implant osseointegration. All left rats were randomly subjected to bilateral ovariectomy (OVX) or sham operation. Three, six, and twelve weeks later, implant osseointegration, peri-implant bone tissue, and biomechanical properties of implant were analyzed. Right femurs with implants were used for micro-CT and histological analysis, and left femurs with implants were used for biomechanical test. Micro-CT, histology, and biomechanical test confirmed the destructive effect of OVX on previously osseointegrated implant in rats; when compared to sham-operated rats, peri-implant bone volume, trabecular architecture, bone-to-implant contact ratio, as well as biomechanical parameters decreased progressively within 12 weeks. Results also indicated that the effect of OVX on undisturbed bone (proximal tibiae) was much stronger than that on peri-implant bone. Osteoporosis produced a progressive negative effect on previously osseointegrated implant in distal femora of rats during 12 weeks. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 2426-2432, 2017.

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Section: Introductionmentioning

confidence: 99%

Effect of osteoporosis on fixation of osseointegrated implants in rats

Hua

et al. 2016

J Biomed Mater Res

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“…The histomorphometric results were also not different either between the groups once the osseointegration was established. 2 In aAnother retrospective study with a follow-up to of 3 years and 4 months for assessed 70 implants placed in patients diagnosed with osteoporosis at the lumbar level of the spine and hip., there This study showedreported was a success rate of 97% for the maxilla and 97.3% The rReduction of both bone density and of mineral content of in peripheral bones has been associated with high resorption and atrophy of edentulous jaws, but although no relationship was found has been established with greater increased loss of implants.…”

Section: Disscusiondiscussionmentioning

confidence: 99%

Immediate Implant Placement in a Patient With Osteoporosis Undergoing Bisphosphonate Therapy: 1-Year Preliminary Prospective Study

Siebert

Jurkovič

Statelová

et al. 2015

Journal of Oral Implantology

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The purposes of this preliminary study are to assess the risk of developing bisphosphonate-related osteonecrosis of the jaw (BRONJ) in a patient with osteoporosis using zoledronic acid and to report the results of a 1-year prospective clinical study regarding 5 immediately inserted implants in the anterior mandible. For this comparative prospective study, 24 female patients, aged ≥54 years, were chosen, all with partially edentulous mandibles. Group A consisted of 12 patients with osteoporosis taking zoledronic acid receiving a once-yearly intravenous infusion of zoledronic acid (5 mg). Control group B consisted of 12 other patients without osteoporosis and not taking drugs. In both groups, the remaining teeth were extracted before 120 implants, 3.7-mm wide and 16-mm long, were immediately installed in the interforaminal region of the mandibles. The 1-year implant survival rate was 100%. No apparent necrotic bone was observed among patients receiving zoledronic acid (group A) after implant surgery. Immediate implant osseointegration can be successful in a patient with osteoporosis using bisphosphonates, suggesting the safety of implantology as a treatment modality.

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“…Other authors have also shown that systemic osteoporosis was not considered an important indicator of dental implant outcome under masticatory function [21, 36, 37]. …”

Section: Discussionmentioning

confidence: 99%

Influence of Estrogen Deficiency on Bone Around Osseointegrated Dental Implants: An Experimental Study in the Rat Jaw Model

Giro¹,

Coelho²,

Sales-Pessoa³

et al. 2011

Journal of Oral and Maxillofacial Surgery

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Purpose-The aim of this study was to evaluate the influence of estrogen deficiency on bone around osseointegrated dental implants in a rat jaw model. Materials andMethods-This study utilized 16 female rats, which had the first molars bilaterally extracted and allowed to heal for 30 days prior to implant placement. Sixty days after implant placement, the animals were randomly submitted to sham surgery (SHAM) or ovariectomy (OVX). The animals were euthanized 90 days post-ovariectomy. Bone to implant contact, bone area fraction occupancy between implant threads, mineral density, turnover markers and TRAP positive cells were assessed for both groups.Results-The results showed that OVX group presented a decrease of systemic bone density, alterations on bone turnover markers, and an increase of TRAP positive cells relative to the

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Comparative study of axial and femoral bone mineral density and parameters of mandibular bone quality in patients receiving dental implants

Abstract: We conclude that there is no association between systemic osteoporosis (axial and femur) and parameters of poor mandibular bone quality. The loss of one implant (1.2%) is compatible with the literature and cannot be attributed to systemic osteoporosis.

Cited by 28 publications

References 31 publications

Effect of osteoporosis on fixation of osseointegrated implants in rats

Effect of osteoporosis on fixation of osseointegrated implants in rats

Immediate Implant Placement in a Patient With Osteoporosis Undergoing Bisphosphonate Therapy: 1-Year Preliminary Prospective Study

Influence of Estrogen Deficiency on Bone Around Osseointegrated Dental Implants: An Experimental Study in the Rat Jaw Model

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