Comparison of antioxidant activity in wild plant (Adenophora triphylla) leaves and roots as a potential source of functional foods

Abstract

Adenophora triphylla is commonly used in food materials and oriental medicine as an analgesic, anti-inflammatory, and antitussive. In the present study, the leaves and roots of A. triphylla were extracted with water and ethanol, respectively, to examine the extracts' in vitro antioxidant activities and total phenolic contents, as well as A. triphylla's potential as a new functional food source and safe and inexpensive supply of antioxidants. Different antioxidant tests were employed and the results were compared with ascorbic acid as a standard antioxidant. The total extractable contents of phenolic compounds and flavonoids, which relate to antioxidant activity in medicinal plants, were also measured. The leaf extracts had notable levels of total phenolics and flavonoids and showed high radical and nitrite scavenging activities as well as inhibition activity against enzymes that induce oxidation. These results suggest that A. triphylla leaves are a potential ingredient for food supplements and a natural source of antioxidants.

Anti-Obesity Effect and Action Mechanism ofAdenophora triphyllaRoot Ethanol Extract in C57BL/6 Obese Mice Fed a High-Fat Diet

“…These results are consistent with previous report that ATREE had antioxidant effects in vitro and in vivo. 19,36) This study adds more evidence that ATREE can play a role as an antioxidant reducing oxidative stress in internal body organs.…”

Growth and Physiological Responses of Adenophora triphylla (Thunb.) A.DC. Plug Seedlings to Day and Night Temperature Regimes

“…However, low night temperature in TC showed a negative impact when compared with TA, suggesting elevation in night temperature leads to an increase in phenol [39]. Previous research showed a highest content of phenol (2.34 mg·g −1 , extracted by water) in this species [2]. Choi et al [9] also reported that the highest total phenolic amounts in the butanol extract (9.97 ± 0.73 mg·mL −1 ).…”

“…It is also known as "Sha-shen" in Chinese and "Jan-dae" in Korean. The Chinese crude drug "shajin", extracted from the roots of A. triphylla, is an effective expectorant for the treatment of whooping cough and chronic bronchitis, and its pharmaceutical name is Radix Adenophorae [1,2]. Historically, A. triphylla was used as food to prevent obesity in Korea [2,3].…”

“…The Chinese crude drug "shajin", extracted from the roots of A. triphylla, is an effective expectorant for the treatment of whooping cough and chronic bronchitis, and its pharmaceutical name is Radix Adenophorae [1,2]. Historically, A. triphylla was used as food to prevent obesity in Korea [2,3]. In recent years, many more medicinal effects of A. triphylla have been reported, such as anti-cancerous, anti-diabetic, and antioxidant [4].…”

Separation of Two Cytotoxic Saponins from the Roots of Adenophora triphylla var. japonica by High‐speed Counter‐current Chromatography

“…Previously, it was reported that Adenophorae Radix contains triterpenoids (Du et al ., ; Yao et al ., ), phenolic glycosides (Kuang et al ., ; Koike et al ., ), sterols, alkaloids (Asano et al ., ) and essential oils (Miyazawa et al ., ). Anti‐obesity (Choi et al ., ), anti‐oxidant (Kim et al ., ; Kim et al ., ), anti‐cancer (Lee et al ., ) and anti‐bacterial (Huang, ) activities have been reported for the extract of Adenophorae Radix. Adenophora triphylla var.…”