Comparison of Choroidal Thickness Among Patients With Healthy Eyes, Early Age-Related Maculopathy, Neovascular Age-Related Macular Degeneration, Central Serous Chorioretinopathy, and Polypoidal Choroidal Vasculopathy

Abstract

The choroid was thicker in eyes with polypoidal choroidal vasculopathy or central serous chorioretinopathy than in control or age-related maculopathy groups.

Smoking and choroidal thickness in patients over 65 with early-atrophic age-related macular degeneration and normals

“…Consistent with some previous reports, 26,27 we have recently observed decreased choroidal thickness among patients with typical soft drusen, subretinal drusenoid deposits, and early-atrophic age-related macular degeneration compared with normals. 28 Cigarette smoking has been linked to many vascular alterations, including experimental evidence of altered retinal 29 and choroidal 30,31 blood flow, and endothelial reactivity.…”

“…We have recently observed a thinner choroid in patients with signs of early AMD, which is consistent with some previous reports. 26,27 Both smoking history and the presence of early AMD are associated with the development of late AMD, including both geographic atrophy and choroidal neovascularization. 1,[8][9][10][11][12][13]32 Therefore, choroidal thickness may be an additional useful clinical variable in assessing risk of AMD progression or the development of late AMD, particularly considering its apparent anatomic association with these two well-known risk factors.…”

Comparison of subfoveal choroidal thickness in healthy pregnancy and pre-eclampsia

“…[9][10][11] Choroidal thickening was observed in eyes with CSC or polypoidal choroidal vasculopathy and choroidal atrophy was also noted in eyes with age-related macular degeneration. 6,12,13 An association between choroidal thickening and choroidal vascular hyperpermeability was reported in previous studies. 10,14 The cause of CSC development in pregnant women is not fully understood, and angiographic study is limited with respect to possible transplacental transport or lactation.…”

Influence of choroidal thickness on subfoveal choroidal thickness measurement repeatability using enhanced depth imaging optical coherence tomography

“…These findings are anticipated to be beneficial in clarifying the pathophysiology of various ocular diseases. 3,4 Despite advances in mechanization and research about CT, an automated measurement method based on recognition of the choroidal boundary obtained using SD-OCT has not been developed. A few recent studies have reported on the automated segmentation of choroid, whereby experienced observers with a good knowledge of the anatomical structure of the choroid as yet measured CT manually.…”