Comparison of Proinflammatory Cytokine Levels in Gingival Crevicular Fluid around Dental Implants with Ceramic and Titanium Abutments

Negahdari, Ramin; Rahbar, Mahdi; Fakhrzadeh, Vahid; Eslami, Hosein; Akbari, Taleb; Bohluli, Sepideh

doi:10.5005/jp-journals-10024-2135

Cited by 13 publications

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References 13 publications

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“…They showed that levels of IL-1β and IL-6 in the GCF around ceramic abutments were significantly lower in comparison with titanium implants. 20 Abdulwassie and Dhanrajani 21 analyzed patients undergoing dental implant procedures in a retrospective study. They prescribed amoxicillin to all the patients and carried it for 10 days postoperatively.…”

Section: Discussionmentioning

confidence: 99%

Wound Healing in Dental Implant Surgery in Patients with or without Antibiotic Prophylaxis

Shinde

Chansoria

Limaye

et al. 2018

The Journal of Contemporary Dental Practice

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Aim:To assess the association of various clinical parameters and proinflammatory cytokines in the wound-healing process of dental implants with the presence or absence of antibiotic prophylaxis. Materials and methods:The present study included evaluation of early wound-healing process in patients undergoing dental implant placement procedures with and without antibiotic prophylaxis. A total of 50 patients with partial edentulous arch were included in the present study. All the subjects were broadly divided into two study groups depending upon the presence or absence of prophylactic antibiotic therapy, with 25 patients in each group. One group consisted of subjects who were given prophylactic amoxicillin (2 gm), 1 hour before the starting of the surgery, followed by 500 mg 3 times a day for 1 week. Detection of interleukin (IL)-1β and -8 cytokine levels in the gingival crevicular fluid (GCF)/peri-implant crevicular fluid (PICF) was done immediately after the dental surgery. All the results were compiled and analyzed by Statistical Package for the Social Sciences (SPSS) software version 17.0.Results: A significant increase in the PICF IL-1β concentration at postoperative follow-up time was observed in the antibiotic group in comparison with the baseline values. A significant increase in the IL-8 concentration postoperatively in comparison with the baseline values in the antibiotic group was also observed. At the time of surgery, the IL-8 concentrations were statistically lower in the antibiotic group in comparison with the other study group. Concentration of amoxicillin, as observed by high-performance liquid chromatography (HPLC), was lower than the minimum detection levels. Conclusion:Detection of amoxicillin is not feasible within the GCF samples immediately after dental surgery procedure.Clinical significance: Clinical usefulness of prophylactic use of amoxicillin is still doubtful.

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Section: Discussionmentioning

confidence: 99%

Wound Healing in Dental Implant Surgery in Patients with or without Antibiotic Prophylaxis

Shinde

Chansoria

Limaye

et al. 2018

The Journal of Contemporary Dental Practice

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“…This finding indicates that central obesity and decompensated heart failure can intensify the risk of OSA. [7,8,27,28] A definitive diagnosis of OSA is done by polysomnography, but this method is time-consuming and requires special laboratory measures, so OSA remains unknown and is not treated in most cases. This method is based on the number of abnormal breathing events that occur every hour of sleep, which is referred to as the apnea-hypopnea index (AHI).…”

Section: Research Articlementioning

confidence: 99%

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Molaei¹

2018

AJP

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Introduction: The disease is one of a variety of respiratory disorders during sleep. This disorder caused by the obstruction of the upper airways leads to a reduction in nighttime oxygenation and sleep disruption during the night. In this study, using cone-beam computed tomography (CBCT) images in patients with obstructive sleep apnea (OSA), we compared their airway volume and length with healthy people. Methodology: This descriptive cross-sectional study was carried out on CBCT scans of 50 patients (25 patients with OSA and 25 healthy subjects) who referred to the

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“…[8,[25][26][27][28][29] The intrastriatal injection of 6-hydroxydopamine (6-OHDA) at a predetermined dosage in rats results in progressive and gradual loss of dopaminergic neurons in the substantia nigra whose trend is similar to the neuropathology of the Parkinson's disease and is considered as a valid empirical model for showing the stages of the onset of the disease. [9,[30][31][32][33][34] The neurotoxin 6-OHDA through producing free radicals, which in turn have cytotoxic effect, disrupts calcium homeostasis by increasing the penetration or exacerbation of release from intracellular reserves, [10,35,36] affecting the genetic regulation and induction of apoptosis [11,[37][38][39][40] and causing neuronal death. For the last three decades, levodopa has been employed as the best medicine for Parkinson's treatment.…”

Section: Research Articlementioning

confidence: 99%

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Aslani¹

2018

AJP

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Background and Objectives: Parkinson's disease through abnormalities in the body's control centers causes symptoms such as tremor at rest, bradykinesia, muscular rigidity, and postural instability. The disease occurs due to the degeneration of cells secreting a substance called dopamine (catecholamine neurotransmitter). The purpose of this study was to investigate the effect of a session of endurance training with three different intensities on cerebral dopamine neurotrophic factor (CDNF), superoxide dismutase (SOD), and malondialdehyde (MDA) levels of cerebral cortex in male rats. Materials and Methods: The rats were divided into two main control and training groups. The training group consisted of low-, moderate-, and high-intensity trainings. The training groups (three groups with 24 rats in total), after getting acquainted with the rodent treadmill, were dealt with an acute training session with three different intensities. The CDNF level of the cerebral cortex was measured by ELISA assay, and the SOD and MDA levels of cerebral cortex by spectrophotometry. Data were analyzed using oneway analysis of variance and least significant difference post hoc test. Results: The acute training with different intensities significantly increases the CDNF and SOD levels of cerebral cortex and prevents the increase in MDA level of cerebral cortex.

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Comparison of Proinflammatory Cytokine Levels in Gingival Crevicular Fluid around Dental Implants with Ceramic and Titanium Abutments

Cited by 13 publications

References 13 publications

Wound Healing in Dental Implant Surgery in Patients with or without Antibiotic Prophylaxis

Wound Healing in Dental Implant Surgery in Patients with or without Antibiotic Prophylaxis

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