Comparison of quality of facial scars after single low-level laser therapy and combined low-level with high-level (PDL 595 nm) laser therapy

Abstract

The main goal of our study was to compare the quality of resulting facials scar 12 weeks after single and combined laser therapy. Forty-one children from age 1.5 to 5 years with facial scars after injury participated in the study. Thirty-one underwent laser therapy, 14 were treated using single low-level laser therapy (670 nm, fluence 3-5 J/cm(-2) ), and 17 underwent combined high-level laser therapy with non-ablative pulsed dye laser (PDL; 595 nm, spot size 7 mm, delay 0.45 ms or 1.5 ms, fluence 9-11 J/cm(-2) , cryogen spray/delay 20/30 ms) and low-level laser therapy. The control group consisted of 10 untreated children. Before treatment and at week 4, 8, and, 12 the scars were evaluated using the POSAS questionnaire. A statistically significant improvement in scars (between ratings before treatment and 4 weeks after therapy, before treatment and 8 weeks after therapy and before treatment and 12 weeks after therapy) was observed in all parameters in both treatment groups (p < 0.0001). For the HLLT+LLLT group the most significant enhancement in the quality of scars was found for all items and at all evaluations, except pigmentation and pliability. There was no improvement observed in quality of facial scars in the control group.

Nonvascular uses of pulsed dye laser in clinical dermatology

“…The authors surmise the use of PDL lasers in keloid scars, demonstrating PDL and ablative lasers (such as the CO 2 laser) are the most widely trialed lasers for keloid scars . We reviewed 22 studies over the last 20 years for the use of PDL independently or in comparison or conjunction/comparison to Erbium‐glass laser, fractional CO 2 laser, Nd:YAG, botulinum toxin, KTP, low‐level laser, different parameters and wavelengths of PDL, triamcinolone/5‐FU, IPL in 477 scars including: hypertrophic, keloidal, burns, and traumatic.…”

“…Vranova et al used the Patient and Observer Scar Assessment Scale (POSAS) to demonstrate the effectiveness of single low‐level laser therapy and combination low‐level laser therapy with PDL vs the control (untreated group). The treated arm of the study demonstrated a significant improvement ( P < 0.001) in the facial scars . Nouri et al assessed the value of early laser intervention by using PDL to treat surgical scars commencing on the day of suture removal.…”

Improved Wound Remodeling Correlates with Modulated TGF‐beta Expression in Skin Diabetic Wounds Following Combined Red and Infrared Photobiomodulation Treatments

“…Overall, it appears that PBM treatments are effective at promoting an anti-scarring and regenerative wound healing response. These observations are further strengthened by the popular use of current clinical dermatological laser procedures including laser scar revisions and nonthermal, light-based facial rejuvenations techniques that have shown consistent esthetic efficacy (40)(41)(42)(43).…”

Histological Demonstration of Bone Healing in Rat Tibiae Influenced by Diode Laser Irradiation

“…In recent years, dental lasers have been used to treat a variety of dental diseases, and the widespread use of lasers in dentistry is growing steadily. The clinical applications of dental lasers are classified into the following two methods: high energy laser irradiation (HLLT: high level laser therapy) 1) used to ablate tissues, and low energy laser irradiation (LLLT: low level laser therapy) 1) used to alter cellular function. It is especially noteworthy that LLLT can be applied for regeneration therapy of several tissues 2) .…”

“…Diode lasers have wavelengths in the near infrared range (700-900 nm) and can penetrate to a depth of 2 to 3 cm depending on the target tissue 3) . For these reasons, diode lasers can be used for TMD (Temporo-mandibular disorder) pain relief 4,5) , promoting wound healing 6,7) , cell growth 8,9) as well as soft tissue ablation with HLLT 1) . Although diode lasers have been beneficial for dental treatment in a variety of clinical situations, there is a paucity of studies reporting on the cellular mechanisms following LLLT irradiation.…”