Comparison of small airways disease measures between frequent and infrequent COPD exacerbators

Gove, Kerry; Conway, Joy; Ostridge, Kristoffer; Paas, Karlien H. W.; Staples, Karl J.; Thompson, Bruce; Wilkinson, Tom

doi:10.1183/13993003.congress-2019.pa1120

Cited by 1 publication

(2 citation statements)

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“…As highlighted by the ATLANTIS study, each single variable is likely to provide different mechanistic insights and this needs further investigation. In the previously mentioned study by GOVE et al [93], only ventilation heterogeneity in the acinar lung zone was different between frequent and infrequent COPD exacerbators, out of 12 parameters tested.…”

Section: Small Airwaysmentioning

confidence: 77%

“…The notion that assessing SAD could harbour predictive value, and help to identify early stages and distinct phenotypes is also the subject of intense investigation in COPD [91]. Evaluating FOT parameters may have a predictive value in distinguishing COPD patients in Global Initiative for Chronic Obstructive Lung Disease grade 1 from non-COPD controls [92], while MBW parameters were found to be higher in frequent than infrequent COPD exacerbators [93]. A combination of IOS, MBW and spirometry could also help to delineate clusters of COPD phenotypes according to predominant features of emphysema, central obstruction or SAD [94].…”

Section: Small Airwaysmentioning

confidence: 99%

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ERS International Congress, Madrid, 2019: highlights from the Airway Diseases, Asthma and COPD Assembly

et al. 2020

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The European Respiratory Society (ERS) International Congress 2019 in Madrid, Spain, was a platform for scientific discussion of the highest quality scientific research, cutting-edge techniques and innovative new therapies within the respiratory field. This article discusses some of the high-quality research studies presented at that Congress, with a focus on airway diseases, including asthma, COPD, small airways, bronchiectasis and cough, presented through the Airway Diseases, Asthma and COPD Assembly (Assembly 5) of the ERS. The authors establish the key take-home messages of these studies, compare their findings and place them into context of current understanding.

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Section: Small Airwaysmentioning

confidence: 77%