Comparison of the Antibacterial Properties of Three Mouthwashes Containing Chlorhexidine Against Oral Microbial Plaques: An in vitro Study

Abstract

Background:The mouth provides an environment that allows the colonization and growth of a wide variety of microorganisms, especially bacteria. One of the most effective ways to reduce oral microorganisms is using mouthwashes.Objectives:The aim of this study was to investigate the antibacterial effects of chlorhexidine mouthwashes (manufacture by Livar, Behsa, Boht) on common oral microorganisms.Materials and Methods:In this in vitro study, isolated colonies of four bacteria, including Streptococcus mutans, S. sanguinis, S. salivarius and Lactobacillus casei, were prepared for an antimicrobial mouth rinse test. The tube dilution method was used for determining the minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC).Results:The MICs for Kin gingival, Behsa and Boht mouthwashes were 0.14, 0.48 and 1000 micrograms/mL using the tube method for S. mutans, respectively. The MBCs for the mentioned mouthwashes were 0.23, 1.9 and 2000 micrograms/mL for S. mutans, respectively. The MICs for Kin gingival, Behsa and Boht mouthwashes were 0.073, 0.48 and 250 micrograms/mL using the tube method for S. sanguinis, respectively. The MBCs for the mentioned mouthwashes were 0.14, 1.9 and 1000 micrograms/mL for S. sanguinis, respectively.Conclusions:The Kin Gingival chlorhexidine mouthwash has a greater effect than Behsa and Boht mouthwashes on oral microorganisms and is recommended to be used for plaque chemical inhibition.

Antibacterial Activity of Buah Merah (Pandanus conoideus Lam.) Against Bacterial Oral Pathogen of Streptococcus sanguinis ATCC10556, Streptococcus mutans ATCC 25175, and Enterococcus faecalis ATCC 29212: An in Vitro Study

“…as shown in Table 1, showed that all factions contained different components. Research data gave support that a previous study indicated flavonoids as an important antimicrobial compound [26].…”

Use of nystatin and chlorhexidine in oral medicine: Properties, indications and pitfalls with focus on geriatric patients

“…Dysgeusia and burning sensation are among the other common side effects, both of which are temporary . Also, resistance of Streptococcus mutans to chlorhexidine has been reported …”

Antimicrobial activities of mouthwashes obtained from various combinations of Elettaria cardamomum Maton., Lavandula angustifolia Mill. and Salvia triloba L. essential oils

“…They are considered as the most sufficient and safe formulations which can deliver molecules able to reduce oral bacteria delivery systems (Sekita et al, 2016). Normally, the combination of mouthwashes (Yousefimanesh et al, 2015) and mechanical oral hygiene such as brushing and flossing is applied to prevent various oral disorders such as infection, inflammation, relieve pain and decrease halitosis. In general, mouthwashes contain antiseptics that are used in the treatment of such infections (Alshehri, 2018;Parashar, 2015).…”