Comparison of the Standard and Structured Interview Guide for the Hamilton Depression Rating Scale in Depressed Geriatric Inpatients

Moberg, Paul J.; Lazarus, Lawrence W.; Mesholam, Raquelle I.; Bilker, Warren B.; Chuy, Ismael Lee; Neyman, Ida; Markvart, Virginia

doi:10.1097/00019442-200102000-00006

Cited by 133 publications

(84 citation statements)

References 18 publications

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“…The inclusion criterion for depression was HAMD ≥ 15 (24-item Hamilton Rating Scale for Depression [26, 27] ). The exclusion criteria, including high suicide risk, possible dementia (assessed with the Mini-Cog [28] ), bipolar disorder, and psychotic disorder, are described in our earlier paper.…”

Section: Methodsmentioning

confidence: 99%

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Six-Month Postintervention Depression and Disability Outcomes of in-Home Telehealth Problem-Solving Therapy for Depressed, Low-Income Homebound Older Adults

et al. 2014

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Background Despite their high rates of depression, homebound older adults have limited access to evidence-based psychotherapy. The purpose of this paper was to report both depression and disability outcomes of telehealth problem-solving therapy (tele-PST via Skype video call) for low-income homebound older adults over 6 months postintervention. Methods A 3-arm randomized controlled trial compared the efficacy of tele-PST to in-person PST and telephone care calls with 158 homebound individuals who were aged 50+ and scored 15+ on the 24-item Hamilton Rating Scale for Depression (HAMD). Treatment effects on depression severity (HAMD score) and disability (score on the WHO Disability Assessment Schedule [WHODAS]) were analyzed using mixed-effects regression with random intercept models. Possible reciprocal relationships between depression and disability were examined with a parallel-process latent growth curve model. Results Both tele-PST and in-person PST were efficacious treatments for low-income homebound older adults; however the effects of tele-PST on both depression and disability outcomes were sustained significantly longer than those of in-person PST. Effect sizes (dGMA-raw) for HAMD score changes at 36 weeks were 0.68 for tele-PST and 0.20 for in-person PST. Effect sizes for WHODAS score changes at 36 weeks were 0.47 for tele-PST and 0.25 for in-person PST. The results also supported reciprocal and indirect effects between depression and disability outcomes. Conclusions The efficacy and potential low cost of tele-delivered psychotherapy show its potential for easy replication and sustainability to reach a large number of underserved older adults and improve their access to mental health services.

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Section: Methodsmentioning

confidence: 99%

“…The 24-item HAMD consists of the GRID-HAMD-21 structured interview guide [26] augmented with three additional items assessing feelings of hopelessness, helplessness, and worthlessness, with specific probes and follow-up questions developed by Moberg et al [27] …”

Section: Methodsmentioning

confidence: 99%

Six-Month Postintervention Depression and Disability Outcomes of in-Home Telehealth Problem-Solving Therapy for Depressed, Low-Income Homebound Older Adults

et al. 2014

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“…All study participants completed all study measures at baseline (day 0, prior to EBRT) and at midpoint (19–21 sessions after EBRT initiation), which was the period when initial fatigue intensification was found to peak in our previous study (Saligan et al 2013). All participants were evaluated using the Hamilton Depression Rating Scale (HAM-D; Moberg et al 2001), and the presence of depressive symptoms was considered an exclusion criterion. Fatigue was measured by the highly reliable and valid Functional Assessment of Cancer Therapy-Fatigue (FACT-F; Yellen et al 1997).…”

Section: Methodsmentioning

confidence: 99%

Lower brain-derived neurotrophic factor levels associated with worsening fatigue in prostate cancer patients during repeated stress from radiation therapy

Saligan

Lukkahatai

Holder

et al. 2015

The World Journal of Biological Psychiatry

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Objectives Fatigue during cancer treatment is associated with depression. Neurotrophic factors play a major role in depression and stress and might provide insight into mechanisms of fatigue. This study investigated the association between plasma concentrations of three neurotrophic factors (BDNF, brain-derived neurotrophic factor; GDNF, glial-derived neurotrophic factor; and SNAPIN, soluble N-ethylmaleimide sensitive fusion attachment receptor-associated protein) and initial fatigue intensification during external beam radiation therapy (EBRT) in euthymic non-metastatic prostate cancer men. Methods Fatigue, as measured by the 13-item Functional Assessment of Cancer Therapy-Fatigue (FACT-F), and plasma neurotrophic factors were collected at baseline (prior to EBRT) and mid-EBRT. Subjects were categorized into fatigue and no fatigue groups using a >3-point change in FACT-F scores between the two time points. Multiple linear regressions analysed the associations between fatigue and neurotrophic factors. Results FACT-F scores of 47 subjects decreased from baseline (43.95 ± 1.3) to mid-EBRT (38.36 ± 1.5, P < 0.001), indicating worsening fatigue. SNAPIN levels were associated with fatigue scores (rs = 0.43, P = 0.005) at baseline. A significant decrease of BDNF concentration (P = 0.008) was found in fatigued subjects during EBRT (n = 39). Conclusions Baseline SNAPIN and decreasing BDNF levels may influence worsening fatigue during EBRT. Further investigations are warranted to confirm their role in the pathophysiology and therapeutics of fatigue.

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“…Severity of depression was assessed using the 17-item Hamilton Rating Scale for Depression (HRSD-17; Hamilton, 1960), a 17-item semi-structured interview. The Structured Interview Guide for the HRSD (SIGH-D; Williams, 1988) was used; this measure shows excellent inter-rater reliability (Williams, 1988), and appears more reliable than the unstructured HRSD (Moberg et al, 2001). Overall illness severity was determined using the CGI (Guy, 1976).…”

Section: Methodsmentioning

confidence: 99%

An exploration of economic reasoning in hoarding disorder patients

Tolin

Villavicencio

2011

Behaviour Research and Therapy

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Current models of Hoarding Disorder (HD) emphasize problems of decision-making. Evidence for neuropsychological impairment in HD, however, has been mixed. The present study examined whether HD patients show problems of economic reasoning that could be associated with decision-making problems. Forty-two HD patients, 29 obsessive-compulsive disorder (OCD) patients, and 36 healthy control participants completed the Iowa Gambling Task (IGT), a computerized card playing game that assesses participants' ability to learn and utilize a rule of sacrificing short-term gain for long-term gain, and a cognitive dissonance reduction task that measured changes in preference for items (art prints) after selecting or rejecting them. Results showed no deficits on the IGT for HD participants, and no difference in dissonance reduction results after selecting or rejecting items on the dissonance reduction task. Furthermore, performance on these two tasks was unrelated to hoarding symptom severity or self-reported indecisiveness. It is suggested that the problems of cognitive processing in HD patients may be largely related to as-yet understudied processes, including idiosyncratic categorization problems for personally-owned items as well as other aspects of economic reasoning.

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Comparison of the Standard and Structured Interview Guide for the Hamilton Depression Rating Scale in Depressed Geriatric Inpatients

Cited by 133 publications

References 18 publications

Six-Month Postintervention Depression and Disability Outcomes of in-Home Telehealth Problem-Solving Therapy for Depressed, Low-Income Homebound Older Adults

Six-Month Postintervention Depression and Disability Outcomes of in-Home Telehealth Problem-Solving Therapy for Depressed, Low-Income Homebound Older Adults

Lower brain-derived neurotrophic factor levels associated with worsening fatigue in prostate cancer patients during repeated stress from radiation therapy

An exploration of economic reasoning in hoarding disorder patients

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