Comparison of Tricalcium Phosphate and Frozen Allogenic Bone Implants in Man

Abstract

As part of their treatment, eight patients with 47 infrabony pockets and horizontal bone defects had 29 tricalcium phosphate and 18 frozen allogenic bone implants placed. One year after surgery the sites were reentered. At the tricalcium phosphate implant sites the average amount of bone apposition was 1.2 mm and pocket depth induction 1.8 mm; 38% of the pockets remained deeper than 3.0 mm. At the allogenic bone sites the average amount of bone apposition was 1.5 mm and pocket depth reduction was 2.0 mm; 22% of the pockets remained deeper than 3.0 mm. The implant materials were well tolerated and there were no complications during the period of the study. Though storage and handling of tricalcium phosphate was simpler, use of allogenic bone led to greater bone apposition and reduction in pocket depth.

Bone Replacement Materials and Techniques Used for Achieving Vertical Alveolar Bone Augmentation

“…Over the years β-TCP has gained high acceptance as a bone filler material despite results not always being predictable. When a direct comparison is made, the allogenic grafts appear to outperform β-TCP in terms of resorption and bone formation [275]. There is evidence that TCP granules undergo fibrous tissue encapsulation and do not stimulate bone growth adequately [104,105].…”

“…There is evidence that TCP granules undergo fibrous tissue encapsulation and do not stimulate bone growth adequately [104,105]. On the other hand, some studies reported bone deposition with β-TCP [275,276,277]. Vertical and horizontal ridge augmentation using α and/or β TCP has been evaluated in animal and clinical studies with variable results [278,279,280].…”

"In vitro" Dissolution of Coral in Peritoneal or Fibroblast Cell Cultures

“…To limit the use of bone autografts, various materials have been used: ,B tricalcium phosphate (Strub et al, 1979), hydroxyapatite in porous or non-porous form (Yukna et al, 1985;Kenney et al, 1986) and more recently in natural coral (Yukna, 1994;Mora and Ouhayoun, 1995). This material, made of calcium carbonate in the aragonite crystalline form, was used for its biocompatibility, osteoconduction, and speed of resorption (Guillemin et al, 1987(Guillemin et al, , 1989.…”

Biomaterials Used As Bone Graft subtitutes

“…First, compression with slowly increasing pressure reduces the inter particle spaces, followed by a sintering process at a temperature of 1100 0 C to 1500 0 C (Osborn and Newesely , 1980) (1). A porous hydroxyapatite is also obtained by a hydrothermal exchange process in which natural coral calcium carbonate of genus porites is converted into hydroxyapatite (14). a.…”