Component- vs. application-level MVC architecture

Tao, Yonglei

doi:10.1109/fie.2002.1157950

Cited by 9 publications

(1 citation statement)

References 7 publications

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“…This paper proposes a generic, layered and component based software architectural style [41,42] for creating software applications which could initiate addressing a) and b) above. However, the most important role of the software architecture (SA) is to focus on sharing of data and knowledge across wider problem domains in biomedicine and pharmacology, and reusing existing computational models, with their data repositories for enabling more efficient discoveries of data for drug repurposing.…”

Section: Introductionmentioning

confidence: 99%

Software Architectures and Efficient Data Sharing for Promoting Continuous Drug Re-purposing

Juric

Fuh²,

Kim³

2021

Proceedings of the Annual Hawaii International Conference on System Sciences

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The proposed layered and component based software architectural style enables data sharing and accessibility of computational software components across Biomedical Science problem domains. It also opens the door to translational informatics, which bridges the gap between knowledge, generated in biomedical science, and clinical practices. Software applications created from the proposed software architectural style, are able to support continuous drug repurposing. They exploit the semantic, which exists, and is available across biomedical problem domains, between drug chemical compounds, their biological targets, particularly unintentional targets and drug therapeutic effects. The excerpt from the proposed software architecture has already been deployed in a computationally light-weight software application, which manages drug repurposing through reasoning upon the available semantic. However a full scale implementation and full deployment of the software architecture, plus data sharing across the spectrum of biomedical research and disciplines, would require some changes in the way therapeutic drugs are discovered, tested and approved.

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Section: Introductionmentioning

confidence: 99%