Composite coatings of lanthanum-doped fluor-hydroxyapatite and a layer of strontium titanate nanotubes: fabrication, bio-corrosion resistance, cytocompatibility and osteogenic differentiation

Qiao, Hongchao; Zou, Qingshuang; Yuan, Cuifang; Zhang, Xuejiao; Han, Shuguang; Wang, Zhenhui; Bu, Xiaopei; Tang, Hui; Huang, Yong

doi:10.1016/j.ceramint.2018.06.090

Cited by 24 publications

(5 citation statements)

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“…Recently, the combination of substituted HAp with nanostructures has also opened new possibilities in the field of coatings for orthopedic purposes. [17][18][19] This review is devoted to the performance of substituted HAp coatings for orthopedic and dental devices. Beginning from the bioinorganic characteristics of the substituents and the most frequently applied coating methods, the in vitro and in vivo biological performance are comprehensively reviewed and analyzed.…”

Section: Introductionmentioning

confidence: 99%

Substituted hydroxyapatite coatings of bone implants

2020

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Section: Introductionmentioning

confidence: 99%

Substituted hydroxyapatite coatings of bone implants

2020

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“…Polishing techniques [4,5], or laser treatments [6] may be used to enhance the roughness and the hydrophilicity of the metallic substrate, that are known to induce better cell adhesion. Anodization of the surface to form titanium oxide nanotubes is also developed [7][8][9], as TiO 2 nanotubes enhance cell growth. Another approach is to coat the metallic surface with calcium phosphate material, due to its similarity with bone.…”

Section: Introductionmentioning

confidence: 99%

Baicalein-modified hydroxyapatite nanoparticles and coatings with antibacterial and antioxidant properties

Palierse

Hélary

Krafft

et al. 2021

Materials Science and Engineering: C

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Aseptic loosening and bacterial infections are the two main causes of failure for metallic implants used for joint replacement. A coating that is both bioactive and possesses antimicrobial properties may address such shortcomings and improve the performance of the implant. We have sought to study the properties of combining hydroxyapatite-based nanoparticles or coatings with baicalein, a plant-extracted molecule with both antibacterial and antioxidant properties. (B-type) carbonated hydroxyapatite nanoparticles prepared by a chemical wet method could subsequently adsorbed by soaking in a baicalein solution. The amount of adsorbed baicalein was determined to be 63 mg.g -1 by thermogravimetric measurements. In a second approach, baicalein was adsorbed on a biomimetic calciumdeficient hydroxyapatite planar coating (12 m thick) deposited on Ti6Al4V alloy from an aqueous solution of calcium, phosphate, sodium and magnesium salts. Soaking of the hydroxyapatite coated on titanium alloy in a baicalein solution induced partial dissolution/remodeling of the upper surface of the coating. However, the observed remodeling of the surface was much more pronounced in the presence of a baicalein solution, compared to pure water. The presence of adsorbed baicalein on the HAp layer, although it could not be precisely quantified, was assessed by XPS and fluorescence analysis. Planar coatings exhibited significant antibacterial properties against Staphylococcus epidermidis. Baicaleinmodified nanoparticles exhibited significant antioxidant properties. These results illustrate the potential of hydroxyapatite used as a carrier for natural biologically-active molecules and also discuss the challenges associated with their applications as antibacterial agents.

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“…Nano strontium-titanate is also reported to increase hydrophilicity in biomedical applications, so (PCL/chitosan/nSrTiO 3 ) also showed good wettability with a contact angle of 27.468° [42]. Nano Anatase TiO 2 with hydrophilic properties also enhanced the wettability of coated surface and expressed a 36.932° contact angle [43,44].…”

Section: Contact Anglementioning

confidence: 97%