Composition of the essential oils of three Uzbek Scutellaria species (Lamiaceae) and their antioxidant activities

Abstract

The chemical composition of the essential oils obtained from aerial parts of Scutellaria immaculata Nevski ex Juz., Scutellaria ramosissima M. Pop. and Scutellaria schachristanica Juz. (Lamiaceae) growing wild in Uzbekistan was analysed by GC and GC-MS. The main constituents of the essential oils from S. immaculata were acetophenone (30.39%), eugenol (20.61%), thymol (10.04%) and linalool (6.92%), whereas constituents of the essential oils fromS. schachristanica were acetophenone (34.74%), linalool (26.98%) and eugenol (20.67%). The S. ramosissima oil is dominated by germacrene D (23.96%), β-caryophyllene (11.09%), linalool (9.63%) and hexadecanoic acid (8.34%). The essential oils of Scutellaria species exhibited weaker antioxidant effects in DPPH, ABTS and FRAP assays. In FRAP assay, only eugenol exhibited a substantial reducing power IC = 2476.92 ± 15.8 (mM Fe(II)/g).

Chemical Constituents and Biological Activities of Essential Oils of Hydnora africana Thumb Used to Treat Associated Infections and Diseases in South Africa

“…The IC50 value for the ABTS radical scavenging activity of the essential oil was 0.55 mg/mL, while those of the standards could not be determined precisely as they were lower than the lowest concentration tested. This result here is similar to the work by Mamadalievaa et al [17] who found that three Uzbek Scutellaria species also exhibited weak ABTS radical scavenging activity. The nitric oxide radical scavenging activities of the essential oil and the reference compounds are presented in Figure 4.…”

Papaya extract upregulates the immune and antioxidants‐related genes, and proteins expression in milk somatic cells of Friesian dairy cows

“…The antioxidant activity of C. papaya might be mediated through various systems, for example, metal chelation, hydroxyl radical destruction and impact cellular repair catalysts or reaction with peroxyl radicals (Sagnia et al, ). The findings of the present GC‐MS analysis of CPE revealed the prevalence of oleic acid and eugenol that have antioxidant properties (Elagbar, Naik, Shakya, & Bardaweel, ; Mamadalieva, Sharopov, Satyal, Azimova, & Wink, ). Eugenol act by preventing the free radical formation, remove radicals before damage can occur, repair oxidative damage and eliminate damaged molecules (Ali et al, ).…”

Aromatic Medicinal Plants of the Lamiaceae Family from Uzbekistan: Ethnopharmacology, Essential Oils Composition, and Biological Activities

“…The flavonoids of this species have been well studied [ 32 ]. Constituents of the essential oil of the aerial parts of S. immaculata growing in Uzbekistan were reported as including acetophenone (30.39%), eugenol (20.61%), thymol (10.04%), linalool (6.92%), 1-octen-3-ol (2.89%), 4-vinylguaicol (2.50%), and 1,8-cineol (2.25%) ( Table 1 ) [ 33 ].…”

“…The chloroform extract of S. ramosissima showed potent cytotoxic effects to Trypanosoma brucei TC221, and HeLa, HepG-2, and MCF-7 cancer cells [ 32 ]. The essential oils from S. ramosissima showed that germacrene D (23.96%), β-caryophyllene (11.09%), linalool (9.63%), hexadecanoic acid (8.34%), caryophyllene oxide (5.90%), eugenol (5.29%), acetophenone (4.67%), thymol (3.01%), and 4-vinylguaicol (2.42%), were the principal components ( Table 1 ) [ 33 ].…”

“…However, the essential oils obtained from the aerial parts of S. schachristanica exhibited weaker antioxidant effects in the DPPH, ABTS, and FRAP assays. The oil of the Uzbek S. schachristanica was reported to be largely composed of acetophenone (34.74%), linalool (26.98%), eugenol (20.67%), 1-octen-3-ol (3.73%), β-terpineol (3.57%), 2-methoxy- p -cresol (1.89%), and 4-vinylguaicol (1.64%) ( Table 1 ) [ 33 ].…”