Comprehensive characterisation of phenolics from Nitraria sibirica leaf extracts by UHPLC-quadrupole-orbitrap- MS and evaluation of their anti-hypertensive activity

Ultrasonic‐assisted extraction of flavonoids from Nitraria sibirica leaf using response surface methodology and their anti‐proliferative activity on 3T3‐L1 preadipocytes and antioxidant activities

“…Our previous study have shown that N. sibirica leaf ethanolic extract contained an abundant amount of phenolics, such as rutin, diosmin, diosmetin, ferulic acid, and chlorogenic acid (Turghun et al, 2020). Some findings suggested that anthocyanin could potentially be used in the treatment of obesity by inhibiting adipocyte formation and proliferation.…”

“…Moreover, the rutin has a significant antioxidant activity against DPPH radical scavenging compared to other radical scavenging (superoxide anion and hydroxyl) (Peng et al., 2018; Wu et al., 2017). More interestingly, rutin has a higher content in the ethanolic extract of N. sibirica leaves (Turghun et al., 2020). Thus, the DPPH test was used in our study to determine more effective extraction part from N. sibirica .…”

“…There have been some investigations into the lipid‐lowering activity of flavonoids, which inhibit adipocyte proliferation and lower plasma cholesterol and triglycerides (Bu et al., 2020; Peluso, 2006). In particular, the Nitraria sibirica leaf extract (NLE) containing some flavonoids showed lipid‐lowering activity by reducing the plasma cholesterol and triglyceride levels in spontaneously hypertensive rat (SHR) rats (Turghun et al., 2020).…”

Polysaccharides from Nitraria retusa Fruit: Extraction, Purification, Structural Characterization, and Antioxidant Activities

“…In some Asian countries (China, Tunisia, Egypt, Jordan, etc), Nitraria retusa are recognized as medicine and food homologous plants. The extracts from Nitraria retusa fruit (NRF) and leaves have been recognised to be beneficial for the treatment of hypertension, diabetes, irregular menstruation, neurasthenia, and dyspepsia for more than one thousand years [ 1 , 2 , 3 ]. The pharmacological activities are attributed to plentiful antioxidant compositions, including polysaccharides, polyphenols, flavonoids, alkaloids, etc.…”

“…The pharmacological activities are attributed to plentiful antioxidant compositions, including polysaccharides, polyphenols, flavonoids, alkaloids, etc. [ 1 , 2 , 3 ]. It is documented that polysaccharides from a variety of plants have significant biological and therapeutic activities, including antiproliferation, antihyperlipidemic, antitumor effects, and prevention of cardiovascular and cerebrovascular diseases [ 4 , 5 , 6 ].…”