Concentrated hydroxyapatite inks for direct-write assembly of 3-D periodic scaffolds

Michna, Sarah; Wu, Wei; Lewis, Jennifer A.

doi:10.1016/j.biomaterials.2005.02.040

Cited by 244 publications

(146 citation statements)

References 27 publications

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“…The retention of shape by the formed fi laments is basically accomplished by a precise control over the ink viscosity, employing high solids loadings for minimizing the shrinkage during the drying process and, thus, preventing cracking phenomena. In this way, robocasting has been proved suitable for many ceramics such as silica [17], alumina [18], tricalcium phosphate [19] or hydroxyapatite [20], all of which can be easily densifi ed in conventional furnaces in air atmospheres. Furthermore, the challenge of fabricating non-oxide ceramic scaffolds by robocasting has already been demonstrated [21], employing SiC inks containing submicronic SiC powders and 20 wt.…”

Section: Diseño Microestructural De Andamiajes Cerámicos De Sic Sintementioning

confidence: 99%

Microstructural designs of spark-plasma sintered silicon carbide ceramic scaffolds

Román-Manso¹,

Pablos²,

Belmonte³

et al. 2014

Bol. Soc. Esp. Ceram. Vidr.

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Section: Diseño Microestructural De Andamiajes Cerámicos De Sic Sintementioning

confidence: 99%

Microstructural designs of spark-plasma sintered silicon carbide ceramic scaffolds

Román-Manso¹,

Pablos²,

Belmonte³

et al. 2014

Bol. Soc. Esp. Ceram. Vidr.

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“…[10][11][12] For reasons given above, honeycomb structures, interconnected rods, fibers, hollow spheres, and porous materials prepared by solid freeform fabrication techniques have not been included in this article. However, Karp, 13 Lee, 14 Michna, 15 Colombo 7 and Scheffler 2 are suggested for those interested in these important cellular structures. It is also worth noting that even though we gathered many examples to illustrate some of the processing routes developed so far, a number of other approaches can be found in the recent literature using similar concepts to those outlined here.…”

Section: Introductionmentioning

confidence: 99%

Processing Routes to Macroporous Ceramics: A Review

Studart

Gonzenbach

Tervoort

et al. 2006

Journal of the American Ceramic Society

1,701

1,143

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Macroporous ceramics with pore sizes from 400 nm to 4 mm and porosity within the range 20%-97% have been produced for a number of well-established and emerging applications, such as molten metal filtration, catalysis, refractory insulation, and hot gas filtration. These applications take advantage of the unique properties achieved through the incorporation of macropores into solid ceramics. In this article, we review the main processing routes that can be used for the fabrication of macroporous ceramics with tailored microstructure and chemical composition. Emphasis is given to versatile and simple approaches that allow one to control the microstructural features that ultimately determine the properties of the macroporous material. Replica, sacrificial template, and direct foaming techniques are described and compared in terms of microstructures and mechanical properties that can be achieved. Finally, directions to future investigations on the processing of macroporous ceramics are proposed.

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“…3 A few criteria have been proposed for an ideal bioscaffold that include biocompatibility, biodegradation, and high porosity with interconnected pores hundreds of microns in diameter to allow tissue ingrowth and nutrient delivery to the newly formed tissue. [4][5][6][7][8][9] Various techniques have been developed to generate porous bioactive ceramic/BG scaffolds, including polymer sponge replication, [10][11][12][13] 3D printing, 14 dry pressing, [15][16][17] freeze casting, 18 and glass fiber sintering. 19 In most of these synthesis methods, melt-quench-derived micrometer-sized BG particles are used as the starting material.…”

mentioning

confidence: 99%

Nanoporosity Significantly Enhances the Biological Performance of Engineered Glass Tissue Scaffolds

Wang

Kowal

Marei

et al. 2013

Tissue Engineering Part A

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Nanoporosity is known to impact the performance of implants and scaffolds such as bioactive glass (BG) scaffolds, either by providing a higher concentration of bioactive chemical species from enhanced surface area, or due to inherent nanoscale topology, or both. To delineate the role of these two characteristics, BG scaffolds have been fabricated with nearly identical surface area (81 and 83 -2 m 2 /g) but significantly different pore size (av. 3.7 and 17.7 nm) by varying both the sintering temperature and the ammonia concentration during the solvent exchange phase of the sol-gel fabrication process. In vitro tests performed with MC3T3-E1 preosteoblast cells on such scaffolds show that initial cell attachment is increased on samples with the smaller nanopore size, providing the first direct evidence of the influence of nanopore topography on cell response to a bioactive structure. Furthermore, in vivo animal tests in New Zealand rabbits (subcutaneous implantation) indicate that nanopores promote colonization and cell penetration into these scaffolds, further demonstrating the favorable effects of nanopores in tissue-engineering-relevant BG scaffolds.

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Concentrated hydroxyapatite inks for direct-write assembly of 3-D periodic scaffolds

Cited by 244 publications

References 27 publications

Microstructural designs of spark-plasma sintered silicon carbide ceramic scaffolds

Microstructural designs of spark-plasma sintered silicon carbide ceramic scaffolds

Processing Routes to Macroporous Ceramics: A Review

Nanoporosity Significantly Enhances the Biological Performance of Engineered Glass Tissue Scaffolds

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