Conceptual disorganization weakens links in cognitive pathways: Disentangling neurocognition, social cognition, and metacognition in schizophrenia

Abstract

Disentangling links between neurocognition, social cognition, and metacognition offers the potential to improve interventions for these cognitive processes. Disorganized symptoms have shown promise for explaining the limiting relationship that neurocognition holds with both social cognition and metacognition. In this study, primary aims included: 1) testing whether conceptual disorganization, a specific disorganized symptom, moderated relationships between cognitive processes, and 2) examining the level of conceptual disorganization necessary for links between cognitive processes to break down. To accomplish these aims, comprehensive assessments of conceptual disorganization, neurocognition, social cognition, and metacognition were administered to 67 people with schizophrenia-spectrum disorders. We found that conceptual disorganization significantly moderated the relationship between neurocognition and metacognition, with links between cognitive processes weakening when conceptual disorganization is present even at minimal levels of severity. There was no evidence that conceptual disorganization-or any other specific disorganized symptom-drove the limiting relationship of neurocognition on social cognition. Based on our findings, conceptual disorganization appears to be a critical piece of the puzzle when disentangling the relationship between neurocognition and metacognition. Roles of specific disorganized symptoms in the neurocognition -social cognition relationship were less clear. Findings from this study suggest that disorganized symptoms are an important treatment consideration when aiming to improve cognitive impairments.

Obsessive–compulsive symptoms interact with disorganization in influencing social functioning in schizophrenia

“…Interestingly, recent studies have suggested a complex interaction between disorganized symptoms and cognitive pathways with a decrease in cognitive functions when conceptual disorganization increases (Minor and Lysaker, 2014). Specifically, conceptual disorganization appears as a moderating factor in the relationship between neurocognition and metacognition (Minor et al, 2015). Future research needs to investigate if the complex interaction between OC and disorganization dimension in influencing functioning may involve cognitive processes.…”

Revisión sistemática (2010-2017) de los instrumentos de evaluación y programas de rehabilitación de la cognición social utilizados con personas con esquizofrenia

“…FEIT, Brown et al, 2014Roberts et al, 2014;Savla et al, 2012;Brekke et al, 2007;Lindenmayer et al, 2013;Rocha & Queirós, 2013;Wang et al, 2013;Sergi et al, 2009;Fuentes et al, 2011;Okruszek et al, 2017;GilSanz et al, 2017;Mervis et al, 2017;Palumbo et al, 2017, MSCEIT: Linke et al, 2015Lin et al, 2013;Minor et al, 2015;Savla et al, 2012;Tso et al 2010;Frajo-Apor, 2016;Lindenmayer et al, 2013;Fanning et al, 2012;Hasson-Ohayon et al, 2015;Rocha &Queirós, 2013;Minor&Lysaker, 2014;Nitzburg et al, 2015;Horan et al, 2012;Rassovsky et al, 2015. The facial affect recognition: Gard et al, 2009; BLERT: Buck et al, 2014;Minor et al, 2015;Buck et al, 2015;Renard et al, 2012;Fanning et al, 2012;Kalin et al, 2015;Thaler et al, 2014;Browne et al, 2016; FEEST: Guastella et al, 2015;Balogh et al, 2014;Sparks et al, 2010;Whitton& Henry, 2013;Vázquez-Campo et al, 2016 2.-Descripción de los instrumentos de la Tabla N°1 (Behere et al, 2008). Instrumento de origen Indio que evalúa expresión y percepción emocional.…”

“…Instrumentos de evaluacIón y programas de rehabIlItacIón de la cognIcIón socIal f. Instrumentos que integran varios subdominios de la Cognición Social. Instrumentoscitados en: The Hinting Task: Fiszdon et al, 2007;Brown et al, 2014;Roberts et al, 2014;Minor et al, 2015;Buck et al, 2015;Vázquez-Campo et al, 2016;Tas et al, 2012;Martínez-Domínguez et al, 2015;Fanning et al, 2012;Rocha &Queirós, 2013;Minor&Lysaker, 2014;Bell et al, 2009;Park & Kim, 2014;Kalin et al, 2015;Thaler et al, 2014;Lysaker et al, 2013b;Bliksted et al, 2014;Maat et al, 2012;Horton&Silverstein, 2008;Donohoe et al, 2012;Browne et al, 2016;Robertson et al, 2013.…”

Schizophrenia and Social Cognition: A Review of Concepts and Treatment Options

“…This refers to a psychotic symptom characterized by loose associations, disrupted goal-directed sequencing, an illogicality [34]. It has been suggested that conceptual disorganization moderates relationships between cognitive processes, especially the control of neurocognition over social cognition [12,34].…”

“…It has been suggested that conceptual disorganization moderates relationships between cognitive processes, especially the control of neurocognition over social cognition [12,34]. As such, conceptual disorganization has recently become a topic of research as a possible treatment target, aiming to improve social impairment in schizophrenics [23,34].…”