Condyloma lata in secondary syphilis

Pourang, Aunna; Fung, Maxwell A.; Tartar, Danielle; Brassard, Alain

doi:10.1016/j.jdcr.2021.01.025

Cited by 20 publications

(13 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We think there may have been an overlap in cutaneous manifestations observed during secondary syphilis. Unfortunately, we did not have the opportunity to examine the genitalia or perianal region during the present hospitalization, which could have provided further evidence of syphilis based on the presence of condyloma lata, skin tag-like growths that arise from mucosal patches in secondary syphilis [ 76 ].…”

Section: Discussionmentioning

confidence: 99%

A Case Report of Secondary Syphilis Co-Infected with Measles: A Diagnostic Dilemma with Fever and Rash

et al. 2022

View full text Add to dashboard Cite

Fever and rash as manifestations of infection by microorganisms are collectively known as febrile exanthem. Since viruses are more frequently associated with fever and rash, these symptoms are thus impetuously termed viral exanthem. However, bacteria represent a frequently overlooked infectious etiology causing rash in humans. In addition, certain microbes may exhibit pathognomonic features that erupt during illness and facilitate clinical diagnosis. Conversely, coinfections often obscure the clinical characteristics of the primary disease and further challenge clinicians attempting to reach a diagnosis. We retrospectively looked at de-identified clinical data of a patient who presented to the Hospital for Tropical Diseases in Bangkok in July 2019 with complaints of fever and rash. The case involved a 35-year-old who presented with a 3-day history of fever, respiratory symptoms, myalgia, conjunctivitis, diarrhea, and a generalized maculopapular rash. On examination, the patient was febrile, tachycardic, and tachypneic, with a mean arterial pressure of 95 mmHg. A differential white blood cell count showed: leukocytes, 5800/µL; neutrophils, 4408/µL; lymphocytes, 406/µL; and platelets, 155,000/µL. Striking findings involving the integumentary system included Koplik’s spots and generalized maculopapular rash. Further serology revealed positive immunoglobulin (Ig)M and IgG for both measles and rubella virus, including reactive serology for Treponema pallidum. Here we describe the clinical course and management of this patient.

show abstract

Section: Discussionmentioning

confidence: 99%

A Case Report of Secondary Syphilis Co-Infected with Measles: A Diagnostic Dilemma with Fever and Rash

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Thus, screening for sexual abuse should be considered in all cases of anogenital and oral warts, first presenting in children older than three to four years [ 106 ]. In addition, differential diagnoses should be considered in case of similar presentations, such as molluscum contagiosum, benign nevi, infantile perianal pyramidal protrusion, and syphilis condylomata [ 108 , 109 , 110 , 111 ]. A study reported that six out of eight children who did not receive treatments experienced spontaneous resolution of condylomas [ 112 ].…”

Section: Hpv In Childhoodmentioning

confidence: 99%

Human Papillomavirus Infection during Pregnancy and Childhood: A Comprehensive Review

et al. 2022

View full text Add to dashboard Cite

Human papillomavirus (HPV), the most prevalent sexually transmitted disease worldwide, is the causative agent for several genital and oropharyngeal cancers and a suspected agent for many malignancies. HPV is associated with several adverse health outcomes during pregnancy. Infants are also at risk of HPV infection via different transmission routes: vertically from an infected mother and horizontally through sexual or non-sexual contact with infected individuals. Several HPV manifestations have been identified during childhood, ranging from common skin infections to severe complications such as juvenile recurrent respiratory papillomatosis. This review aims to provide a comprehensive overview of the epidemiology, manifestations, and treatment strategies of HPV infection during pregnancy and childhood. Moreover, we underline the role of vaccination in preventing complications.

show abstract

“…The clinical stages of syphilis are primary, secondary, early non-primary non-secondary, and unknown duration or late [3] . Condyloma lata may be seen as a manifestation of secondary syphilis in approximately 6 to 23% of patients [1] , [3] , [4] , [5] , [6] . The lesions are highly infectious [3] , [4] .…”

mentioning

confidence: 99%

“…Condyloma lata may be seen as a manifestation of secondary syphilis in approximately 6 to 23% of patients [1] , [3] , [4] , [5] , [6] . The lesions are highly infectious [3] , [4] . They present as moist papules or nodules, with a smooth, verrucous, or hypertrophic surface [3] .…”

mentioning

confidence: 99%

“…Condyloma lata most commonly occur in the anogenital area, the medial thighs, or inframammary creases (areas of skin apposition) [3] . The differential diagnosis includes condyloma acuminata and malignancy (e.g., squamous cell carcinoma) [3] , [4] . Syphilis is typically diagnosed by serology, but a diagnosis can also be confirmed by immunohistopathology or nucleic acid amplification if biopsy of a lesion is obtained [1] , [7] .…”

mentioning

confidence: 99%

See 1 more Smart Citation