Condylomata acuminata of the cervix

Woodruff, J. Donald; Peterson, William F.

doi:10.1016/0002-9378(58)90724-5

Cited by 51 publications

(17 citation statements)

References 7 publications

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“…The cytological details of condylomatous lesions in the genital tract have only recent ly been outlined [II, 12,16], Mutually identical cytological changes are encoun tered in cells derived from three structurally different epithelial lesions; the classical pap illomatous condyloma or genital wart [20], the flat-type condyloma and the 'inverted', endophytic type of condyloma [11,12,16]. All these three lesions have been found to be frequently associated with epithelial dys plasias of varying severity [11.…”

Section: Discussionmentioning

confidence: 99%

“…16]. Three dif ferent histological types of condylomas have been encountered in the human genital tract; the classical papillomatous condyloma or genital wart [20], the inverted, endophyt ic type, and the flat type [12,16], All these different condyloma types have been de scribed to often be associated with epithelial dysplasias [11,12,16] of the uterine cervix. Following these observations, and docu ments on the malignant transformation seen in genital warts [2, 3, 5-10, 17, 18], views have been presented that condyloniatous le sions could represent the precursors of the squamous cell carcinoma of uterine cervix.…”

Section: Introductionmentioning

confidence: 99%

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Condylomatous Changes in Neoplastic Bronchial Epithelium

Syrjänen¹

1979

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The present communication is a report of a case where histological changes, identical to those described recently to be of condylomatous nature in the genital tract, were found in the bronchial epithelium adjacent to an invasive squamous cell carcinoma. The significance of this finding in the light of squamous cell carcinogenesis is discussed, and the conclusion is drawn that these lesions are worth recording until proved to be unrelated to the carcinogenesis, or to be involved in it.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Condylomatous Changes in Neoplastic Bronchial Epithelium

Syrjänen¹

1979

Respiration

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“…All these different warts are known to be induced by human papilloma virus (HPV), the structure and immunological properties of which are well elucidated [1,2,4,5,15,21,25,27,[40][41][42], Duirng the last few years, plenty of data have been accumulated on the genital wart, condyloma acuminatum, dealing with its morphological and cytological manifesta tions [2. 3, 6, 7, 10, 12, 14, 17, 22, 23, 26, 29, 30, 39], The establishment of three dif ferent histological patterns of genital wart (flat, endophytic and papillomatous condy lomas) by Meisels and co-workers [18,19], and the observations on their frequent inti mate association with epithelial dysplasias in the uterine cervix [10,16,18,19,24,[32][33][34]39], substantiated by their recent discovery also in association with invasive squamous cell carcinoma of uterine cervix [31], have all lent support to the idea that HPV could be involved in squamous cell . vl.…”

Section: Introductionmentioning

confidence: 99%

Epithelial Lesions Suggestive of a Condylomatous Origin Found Closely Associated with Invasive Bronchial Squamous Cell Carcinomas

Syrjänen¹

1980

Respiration

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The histology of the bronchial specimens derived from 104 patients with an established invasive bronchial squamous cell carcinoma was assessed with special reference to the detection of the morphological manifestations of human papilloma virus (HPV) recently described in the uterine cervix, i.e., three different types of condylomatous lesions (papillomatous, flat and endophytic). Histological lesions fulfilling the criteria of papillomatous condyloma were found in 6 cases, those of endophytic condyloma in 4 cases, and lesions identical to flat type condyloma of the uterine cervix were encountered in 26 cases (25%). The role of HPV in the development of these lesions and their relationship to squamous cell carcinogenesis was discussed, and a concept hypothesizing the development of bronchial squamous cell carcinoma is outlined.

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“…Histologically, they are characterized by papillomatosis, elongation and thickening of rete pigs, acanthosis, parakeratosis, and cytoplasmic vacuolization. 15 The vast majority of exophytic condylomas appear to be induced by HPV 6 or 11 16 and HPV 6 (65%) seems to be prevalent than HPV 11(21%).…”

Section: Hpv Infections Of the Cervix May Results In Development Of Fomentioning

confidence: 99%

Inverted Condyloma of Uterine Cervix: A Rare Condylomatous Lesion

D¹,

Narmadha²,

Viswanathan³

et al. 2014

jemds

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Human papillomavirus (HPV) is an epitheliotropic virus that can infect and cause disease of skin or mucosa at any site. HPV associated lesions can be broadly divided into cutaneous and mucous membrane lesions. Cutaneous lesions include: warts, Butcher's wart and epidermodysplasia verruciformis. The anogenital diseases, include warts (condyloma), dysplasia (cervical, vaginal, vulvar, anal), and squamous cell carcinoma. Here we are presenting a case report of a 27 year old female who was histologically diagnosed as inverted condyloma a rare condylomatous lesion involving the uterine cervix. KEYWORDS: Inverted Condyloma, uterine cervix. INTRODUCTION:Independent of the site or the type of lesion, the papilloma virus virion has a constant morphology and structure. 1 The virion is a non-enveloped 8 Kb long icosahedral structure of 55-60 nm diameter, which forms paracrystalline arrays in the nucleus of infected cells. 2 Epidemiologic studies show genital warts to be among the most common sexually transmitted diseases, after chlamydia and gonorrhea. The incidence of condyloma acuminatum has been steadily rising over the past three decades. 3 W.H.O. estimates that 630 million people are infected with genital HPV, resulting in a worldwide prevalence of 9-13%. 4 There is an inverse relationship between age and HPV prevalence in many countries. In some countries, cross-sectional and cohort studies have shown a U-shaped curve with a first peak in women under 30 years of age and a second peak in women aged 55-64 years. 5 It is believed that many sexually active adults are infected with HPV, but only 1±2% of them are found to have clinical lesions. Rest of the infections remain subclinical, with the latent HPV residing in the epithelial basal cells. 6 The most important risk factor for genital warts are decreasing age of first sexual intercourse, multiple sexual partners and clinical history of other venereal diseases. 7

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Condylomata acuminata of the cervix

Cited by 51 publications

References 7 publications

Condylomatous Changes in Neoplastic Bronchial Epithelium

Condylomatous Changes in Neoplastic Bronchial Epithelium

Epithelial Lesions Suggestive of a Condylomatous Origin Found Closely Associated with Invasive Bronchial Squamous Cell Carcinomas

Inverted Condyloma of Uterine Cervix: A Rare Condylomatous Lesion

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