Conformational change of hydroxyapatite/gelatin nanocomposite by glutaraldehyde

Calcium orthophosphate-based biocomposites and hybrid biomaterials

“…Thermogravimetric and infrared analysis demonstrated that the polymers were chemically bonded to the HA particles through the isocyanate groups, making it a suitable approach to improve the adhesion [910]. Other researchers used glutaraldehyde as a crosslinked reagent in various calcium orthophosphate-based biocomposites [388,392,500,502,503,520,525,585,621,646,649,917]. The interfacial bonding between calcium orthophosphates and other components might be induced by using various coupling agents and surface modifiers, such as silanes [192,234,337,540,[918][919][920][921][922][923], zirconates [225,337,339,914,924], titanates [225,337,924], phosphoric acid [543], alkaline pretreatment [722,725], polyacids [115,116,234], and other chemicals.…”

Organic/Inorganic bioactive materials Part III: in vitro bioactivity of gelatin/silicocarnotite hybrids

“…Much of the research interests today focus on the fabrication of artificial bone like ceramic/ polymer composites [6][7][8][9] especially on HA/gelatin nanocomposites [1,[10][11][12][13][14][15][16][17][18][19][20][21][22], fluorapatite (FHA)/ gelatin nanocomposites [23], carbonated fluorapatite (CO 3 FHA)/gelatin nanocomposites [24]; drug delivery carrier [25,26] and protein separation [27].…”

Preparation of hierarchically organized calcium phosphate–organic polymer composites by calcification of hydrogel

“…An alternative soaking process in calcium and phosphorous solutions provided the HAp formation in a three-dimensionally structured organic hydrogel matrix at ambient temperature [18,19]. An ordered composite powder of HAp and organic molecules was also prepared through self-organization by interplay at the organic-inorganic interface [20][21][22][23][24][25][26][27][28]. A composite material with a hierarchical structure was fabricated by the self-assembly of nanofibrils of mineralized collagen [29].…”