Congenital Abnormalities in Production Animals

Williams, David L.

doi:10.1016/j.cvfa.2010.09.001

Cited by 11 publications

(10 citation statements)

References 38 publications

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“…That might account for the fact that younger animals appeared more severely affected in comparison to older animals, even though it was not statistically significant. In spite of small number of bulls on this farm, there is a trend showing male animals might be at higher risk for this condition, which is consistent with other reports [ 13 ].…”

Section: Discussionsupporting

confidence: 91%

Congenital cataracts in an Ayrshire herd: a herd case report

et al. 2014

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An Ayrshire dairy herd was investigated for occurrence of ocular abnormalities in new-born calves. Ophthalmic examinations were performed on all the animals in the herd and 26% of them were diagnosed with bilateral cataracts. Cataracts varied in extent and severity but the majority were restricted to the lens nucleus. Epidemiological analysis showed the prevalence was higher in male animals and lower in animals born to heifers. A family tree was designed but no genetic impact of dam lines was evident. Sire data was incomplete and could therefore not be included. Based on the information provided by the farmer there was no obvious environmental or nutritional cause of these cataracts. However, data records were incomplete and further investigation/monitoring of the herd would be needed to establish a cause and enable a better insight into the aetiology of this disease in cattle.

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Section: Discussionsupporting

confidence: 91%

Congenital cataracts in an Ayrshire herd: a herd case report

et al. 2014

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“…A number of authors have reported cases of multiple, concurrent congenital ocular defects including microphthalmia, aphakia, microphakia and retinal dysplasia4 28 29; microphthalmia has also been reported to be present in cases of calves born with congenital abnormalities affecting multiple body systems 7. Congenital ocular abnormalities in cattle have been associated with infection in utero, genetic mutations and maternal hypovitaminosis A during the time of ocular development, and can also occur as a sporadic event 2 3 6 7 16 28 29. Teratogenic toxins have been reported to cause congenital ocular abnormalities in other ruminants,30 but this is rarely reported in cattle.…”

Section: Discussionmentioning

confidence: 99%

“…A number of congenital ocular abnormalities have been described in cattle1–3 and the reported incidence varies from 1 in 2800 births4 to 1 in 50,000 births 1. Microphthalmia has been described both in conjunction with other congenital ocular abnormalities5 and also associated with congenital abnormalities affecting other body systems in cattle 6 7.…”

Section: Introductionmentioning

confidence: 99%

Multiple congenital ocular abnormalities including microphthalmia, microphakia and aphakia in a Simmental cross bull

Gladden

Rodríguez

Marchesi

et al. 2019

Vet Record Case Reports

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A 20-month-old Simmental cross bull presented to the Scottish Centre for Production Animal Health and Food Safety, University of Glasgow School of Veterinary Medicine, in April 2015 with multiple congenital ocular abnormalities including bilateral microphthalmia. We present this case as an interesting presentation of idiopathic multiple congenital ocular abnormalities in the absence of congenital abnormalities affecting other body systems. This case highlights an unusual ocular presentation and illustrates the importance of a thorough clinical examination. The prognosis for cases of multiple congenital ocular abnormalities including microphthalmia is poor as no treatment is available and welfare is often compromised. It is therefore important that cases are accurately diagnosed so appropriate management decisions can be made regarding the individual and any herd investigations that are required can be instigated.

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“…Complete fusion of the cerebral hemispheres and a single dilated "lateral" ventricle is accompanied by the absence of olfactory nerves, bulbs, and peduncles, which is why the malformation is often called arhinencephaly. This severe form has also been termed synophthalmia, focusing on the ocular and ignoring the underlying brain defects (Summers et al 1995;Vandevelde et al 2012;Williams 2010).…”

Section: Congenital Brain Malformations Associated With Internal Hydrocephalus Holoprosencephaly (Arhinencephaly)mentioning

confidence: 99%