Congenital agenesis of seminal vesicle

Over the past few decades, MRI of the prostate has made great strides in improving cancer detection and is being embraced by more clinicians each day. This article aims to review the imaging characteristics of common and uncommon, but consequential lesions involving the seminal vesicles (SV), as seen predominantly on MRI. Many of these findings are seen incidentally during imaging of the prostate. Anatomy and embryology of the SV will be described which will help illustrate the associations of abnormalities seen. Congenital, infectious, neoplastic, and tumor mimics will be explored in detail, with discussion on clinical presentation and treatment strategies.

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“…Corrective surgeries can be performed because testicular spermatogenesis is usually intact and fertility may be salvaged. [9]…”

Section: Congenital Lesionsmentioning

confidence: 99%

Lesions of the Seminal Vesicles and their MRI Characteristics

Reddy

Verma

2014

Journal of Clinical Imaging Science

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“…1 They may be categorized into abnormalities of number (agenesis, fusion, duplication), maturation (hypoplasia), position (ectopia) or structure (diverticulum, cyst, communication with the ureter). 3 In all our patients, normal FSH level confirms, with hypospermia, the obstructive origin of azoospermia. Transrectal ultrasound is the gold standard for SV and internal genitalia assessment in cases of obstructive azoospermia.…”

Section: Discussionmentioning

confidence: 67%

“…2 SV unilateral agenesis is observed in 0.6% to 1% of cases, whereas the incidence of bilateral agenesis remains unknown. 3 These SV abnormalities are often associated with vas deferens agenesis and may also be accompanied by reno-ureteral malformations. 2,3 Internal genitalia agenesis is frequently observed with cystic fibrosis transmembrane regulator (CFTR) gene mutations, 3 which should be searched in each man, and his partner, presenting with related-azoospermia.…”

Section: Introductionmentioning

confidence: 99%

“…3 These SV abnormalities are often associated with vas deferens agenesis and may also be accompanied by reno-ureteral malformations. 2,3 Internal genitalia agenesis is frequently observed with cystic fibrosis transmembrane regulator (CFTR) gene mutations, 3 which should be searched in each man, and his partner, presenting with related-azoospermia. Male infertility due to SV agenesis or hypoplasia has benefited from advances in semen collection techniques and medically-assisted procreation.…”

Section: Introductionmentioning

confidence: 99%

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Seminal vesicle agenesis: An uncommon cause of azoospermia

Bouzouita

Kerkeni

Abouda³

et al. 2014

CUAJ

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Seminal vesicle malformations are a rare cause of obstructive azoospermia, often associated with other internal genitalia and upper urinary tract birth defects. We report 5 new cases of seminal vesicle agenesis in men presenting with hypospermia and azoospermia. Imaging showed seminal vesicle unilateral agenesis in all patients. The remaining seminal vesicle was hypoplastic in 3 cases, dilated in 1 case and with abnormally thick content in another case. Vas deferens agenesis was observed unilaterally in 2 patients and bilaterally in 2 other patients. No renal malformations were detected. Genetic study showed in all cases a 46 XY karyotype without any microdeletions. A single heterozygous cystic fibrosis transmembrane regulator gene mutation was diagnosed in 1 man, but not found in his partner. Intracytoplasmic sperm injection using sperm from a testicular biopsy was performed in 3 couples, without success.

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“…Seminal vesicle agenesis is always associated the anomalies vas deferens. Ectopia of vas deferens can be confirmed only by invasive vasography (6) The differential diagnosis of the seminal vesicle cystic lesions include true cysts of seminal vesicles or prostate, ejaculatory duct cysts, mullerian duct cysts, prostatic utricle cysts, hydronephrotic pelvic kidney and ureteroceles. Differentiating features may include position (median, paramedian or lateral), content, associations (renal agenesis or anomalies of external genitalia) and imaging characteristics (7) …”

Section: Discussionmentioning

confidence: 99%

Cystic Malformation of Seminal Vesicle: Case Report

Kalekar¹,

Khadse²

2013

jemds

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Cystic malformation of the seminal vesicle is rare congenital urogenital tract anomaly. It can be isolated anomaly. It can be associated with other urinary tract anomalies. Clinical presentation may be extremely variable. In symptomatic patients surgical intervention is required so radiological features and clinical aspects are very important for patient's management. CASE REPORT:A 32 yr male patient was admitted with complaints of dysuria, frequency of micturition and intermittent febrile episodes since last two months. A long course of antibiotics was given to him with clinical diagnosis of urinary tract infection. At the time of admission urine examination was normal. Per rectal examination revealed a firm mass located just superior to the prostate.Ultrasound of the abdomen and pelvis was performed which revealed absence of right kidney and hypertrophy of contralateral kidney which was also malrotated and improperly ascended. There was a cystic lesion at the anatomical site of seminal vesicle which is not seen separately, the prostate also appeared smaller in size. Transrectal ultrasound was performed for further characterization which revealed a large tubular cystic lesion entirely replacing the seminal vesicle. There was no solid component. The prostate was well visualized however it was smaller in size.Patient was further investigated with IVU, CT scan and MRI. Intravenous urography revealed absent right kidney and compensatory hypertrophy of left kidney. Left kidney was malrotated and incompletely ascended however it showed prompt and normal excretion. The left ureter and urinary bladder were normal.Plain and post intravenous contrast CT scan of the abdomen was performed. There was hypodense mass lesion of water attenuation in the pelvis at the bladder base more to the right side with non visualization of the seminal vesicles separately. There was no contrast enhancement.Plain MRI was performed using dedicated pelvic coil on 1.5 T GE units. Axial, coronal and sagittal T1W and T2 W sequences were performed. It showed a tortuous tubular structure of fluid signal intensity entirely replacing the seminal vesicles. It measured approximately 8x7x6 cms in size. There was no solid component. The prostate was small in size however appeared normal in morphology and signal characteristics. The rest of the pelvic structures were normal.So based on the imaging findings diagnosis of congenital cystic anomaly of the seminal vesicle was made.

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Congenital agenesis of seminal vesicle

Cited by 17 publications

References 20 publications

Lesions of the Seminal Vesicles and their MRI Characteristics

Lesions of the Seminal Vesicles and their MRI Characteristics

Seminal vesicle agenesis: An uncommon cause of azoospermia

Cystic Malformation of Seminal Vesicle: Case Report

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