Congenital pigment synthesizing melanoma of the scalp

Yun, Sook Jung; Han, Dong; Lee, Min-Cheol; Lee, Jee-Bum; Baek, Hee Jo; Bae, Si Young; Hwang, Tai Ju; Lee, Sam Yong; Lee, Joon Kyoo; Kook, Hoon

doi:10.1016/j.jaad.2008.07.025

Cited by 6 publications

(8 citation statements)

References 17 publications

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“…The frequency of necrosis and its significance as a prognostic factor increases with tumor thickness [28] . Tumor necrosis was seen in5, and ulceration was seen in 6 cases of congenital and infantile malignant melanoma [7] , [8] , [9] , [11] , [17] ; all patients with tumor necrosis had a poor prognosis.…”

Section: Resultsmentioning

confidence: 98%

“…Our literature search revealed 10 cases of congenital [7] , [8] , [9] , [11] , [15] , [16] , [17] , [18] , [19] , and 3 cases of infantile [13] , [20] , [21] malignant melanoma that were located on the scalp. Six of the 10 congenital scalp melanoma cases and one case of infantile melanoma arose from congenital melanocytic nevi, whereas remaining cases were de-novo in origin.…”

Section: Resultsmentioning

confidence: 99%

“…Outcomes of malignant melanoma of scalp are generally unfavourable. Of the thirteen reported cases, 6 expired within 6 months of age [4] , [7] , [8] , [11] , 1 was lost to follow-up and remaining were alive at least till the last follow-up [4] , [9] .…”

Section: Resultsmentioning

confidence: 99%

“…Melanomas of scalp and neck had a particularly poor prognosis [27] . The most common site for congenital and infantile melanoma is also the head and neck region [9] . According to one study, scalp and neck melanomas account for about 6% of all melanomas but are responsible for 10% of all melanoma related deaths [29] .…”

Section: Resultsmentioning

confidence: 99%

“…Congenital and infantile malignant melanomas are the least common variety of pediatric melanomas. Only 36 cases of congenital and infantile melanomas have been reported in literature since 1925 [4] , [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] .…”

Section: Introductionmentioning

confidence: 99%

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Congenital and infantile malignant melanoma of the scalp: A systematic review

Tariq

Shallwani

Waqas

et al. 2017

Annals of Medicine &Amp; Surgery

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Congenital and infantile malignant melanomas are rare and typically carry poor prognosis. The purpose of this article was to review the data on congenital and infantile malignant melanomas of the scalp in order to understand its presentation, diagnosis, management, and outcomes of congenital melanoma of scalp. We searched PubMed, CINAHL and Cochrane databases. Ten cases of congenital and 3 cases of infantile malignant melanoma of scalp were identified. The diagnosis was confirmed by biopsy and histological analysis for confirmation. The prognosis depends on the origin of disease (congenital melanocytic nevus, transplacental metastasis, or de-novo), tumor thickness, the presence of ulceration and/or necrosis, and anatomic site (scalp lesions having poor prognosis). The most commonly used treatment of the reported cases of congenital and infantile melanoma was surgical excision of the primary lesion. Further modes of treatment may be extrapolated from the treatment of childhood and adult melanomas.

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