Congenital prepubic sinus

Pseudo‐clitoromegaly associated with congenital prepubic sinus

“…A consensus concerning the embryology and classification has not yet been reached, because of the discrepancy of anatomic features. 1 Some authors have reported that it represents a tract originating in the skin overlying the pubic symphysis immediately superior to the base of the penis or clitoris and extending to but not communicating with the anterior wall of the bladder. Some cases show symptoms such as emission of pus from the sinus and inflammation.…”

Congenital prepubic sinus—An aborted dorsal urethral duplication or a cloacal remnant?

“…After the first report by Campbell et al, in 1987, around 50 cases are reported in literature [1][2][3][4][5]. Four theories are proposed to explain the etiology of CPS: 1) anomalous abdominal wall closure; 2) a variant of dorsal urethral duplication; 3) a fistula of primitive urogenital sinus and 4) a remnant of primitive cloaca [6][7][8][9]. Routine and immunohistochemical staining of tract in patients reported here and in literature; specifically, the reports by Huang et al, Chou et al and Balster et al, val-idates the presence of transitional, columnar and squamous epithelium in the lining.…”

Congenital prepubic sinus: A variant of dorsal urethral duplication (Stephens type 3)

“…Soares‐Oliveira et al . reported two patients with congenital prepubic sinus 3 . Because the histopathological examination demonstrated that the sinus was lined with stratified squamous epithelium in both cases, they advocated that the etiology of this entity is the midline defect which attributes the origin of the defect to a deficient cloacal membrane replacement by the lateral mesodermic folds as a fructrated bladder extrophy variant.…”