Consideraciones diagnósticas sobre el llamado síndrome del pulmón hiperclaro unilateral (síndrome de Swyer-James o de Mc-Leod)

Abstract

Swyer-James-MacLeod Syndrome (SJMS) is considered to be a relatively uncommon and complex disease characterized by roentgenographic hyperlucency of one lung, lobe, or part of a lobe, due the pulmonary vascular structure and alveolar overdistension. It is sometimes associated with bronchiectasis. This syndrome seems to be an acquired disease that develops after viral bronchiolitis and/or viral pneumonia in early childhood. Microscopically, there is evidence of patchy bronchitis and bronchiolitis.SJMS is usually asymptomatic and discovered accidentally by chest radiography in a child with respiratory symptoms and should be differentiated from other causes of unilateral hyperlucency on chest radiography, such as those related to congenital bronchial and/or vascular abnormalities. Treatment includes early control of lung infections, as well as influenza and pneumococcal vaccination. Few reports of this syndrome in children have been published. We describe the case of a 12-year-old boy with unilateral hyperlucency of the lung and respiratory symptoms of acute pneumonia and discuss the main diagnostic features of this syndrome.

Successful Management of Patient with Treatment Resistant Schizophrenia and Swyer-James-Macleod Syndrome with Clozapine

“…SJMS is characterized by hyperlucency of one lung field along with pulmonary vascular abnormalities, alveolar overdistension and bronchiectasis, bronchiolitis obliterans, or emphysema. [ 3 ] Although the exact etiology of this disorder is not clear, recurrent respiratory infections are speculated as a cause. [ 4 ] These infections include Mycoplasma pneumonia, Bordatella pertussis , influenza A, tuberculosis, measles, respiratory syncytial virus, etc.…”

Successful pregnancy outcome in Swyer-James-Macleod syndrome

“…[13] The suppurative pulmonary infection leads to destruction of bronchial epithelium, muscle and elastic tissue. The resulting loss of ciliary action and therefore impaired bronchial drainage predisposes to secondary infections.…”

“…Therefore, treatment includes early control of lung infections with antibiotics. [36] Surgical treatment is indicated in cases of chronic infection of the damaged lung. [2] In the literature, pneumonectomy[1] or occlusion of the main bronchus by its resection from the affected lung without pneumonectomy[2] are described as treatment modalities.…”

Complication of post-infectious bronchiolitis obliterans (Swyer-James syndrome)

“…[9][10][11] Functionally, SJS is characterized by a decrease in volume during inspiration and air trapping during expiration, which results from bronchiolar obstruction. 12,13 Since this is a rare disease, it is important to understand the overall clinical picture of SJS to exclude the differential diagnosis of other diseases that are associated with bronchiolitis. For this purpose, we hereby report the case of a patient diagnosed with SJS.…”

“…8 There are two types of SJS: asymptomatic, with most cases being diagnosed in adults during routine radiological examinations; and symptomatic, which is most commonly found in children. 13 The clinical manifestations of SJS may vary, but typically include productive cough, dyspnea on exertion, and sometimes hemoptysis. On physical examination, the patient may show hypomobility on the side affected with hypertympanism to percussion, decreased breath sounds, and occasionally crepitant rales.…”