“…Several analytical methods have already been reported for the determination of mefenamic acid including potentiometric, 5 ow injection analysis, 6 spectrophotometry, [7][8][9][10][11] HPLC method, [12][13][14][15][16] stability-indicating HPTLC determination, 17 different chromatographic methods such as TLC-densitometric, 18 RP-HPLC-DAD method, 19 spectrouorimetry method, 20 titration methods, 21 electrochemical sensors, 22 atomic absorption spectrometry, 23 nuclear magnetic resonance spectroscopy 24 and magneto carbon paste electrode. 25 Electrochemical methods are preferred over optical methods because they are relatively rapid, show high sensitivity and selectivity. Recently, several methods have been used for increase selectivity, sensitivity, detection limit and other property of potentiometric sensors.…”