Consumption of chokeberry ( Aronia mitschurinii ) products modestly lowered blood pressure and reduced low-grade inflammation in patients with mildly elevated blood pressure

Loo, Britt-Marie; Erlund, Iris; Koli, Raika; Puukka, Pauli; Hellström, Jarkko; Wähälä, Kristiina; Mattila, Pirjo; Jula, Antti

doi:10.1016/j.nutres.2016.09.005

Cited by 78 publications

(108 citation statements)

References 29 publications

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“…A mixed berry intervention study reported a significant reduction in systolic BP in adults with elevated BP (–1%); while a blueberry beverage intervention reported a more substantial reduction in hypertensive females (–5%) when compared to the control groups. A chokeberry intervention reported a reduction in ambulatory diastolic day BP readings (–2%) in adults with elevated BP, while a blueberry intervention reported a 6% reduction in diastolic BP in hypertensive females . Similarly, a cranberry juice intervention also reported a 6% reduction in diastolic BP in normotensive adults .…”

Section: Resultsmentioning

confidence: 99%

“…Of the 23 RCTs, 17 studies achieved a total of six to eight “A” scores out of a max score of 8. Nine RCTs were either single blinded, did not use a third party to assign randomization, and/or had insufficient allocation concealment . In seven RCTs, a control that was not identical in terms of appearance, taste, and texture was used .…”

Section: Resultsmentioning

confidence: 99%

“…Two studies did not evaluate compliance with the study treatment . Of those that did evaluate participant compliance, four studies included a biomarker of exposure such as plasma quercetin, plasma vitamin C, plasma ellagic acid, and urinary polyphenol metabolites . In terms of attrition, three studies failed to report dropouts, while three other studies reported a dropout rate >20% …”

Section: Resultsmentioning

confidence: 99%

“…Eleven RCTs investigated BP as an outcome (Table ). Out of these, four studies reported significant reductions in BP from baseline for systolic BP. A mixed berry intervention study reported a significant reduction in systolic BP in adults with elevated BP (–1%); while a blueberry beverage intervention reported a more substantial reduction in hypertensive females (–5%) when compared to the control groups.…”

Section: Resultsmentioning

confidence: 99%

“…However, two of the RCTs reporting reductions in BP were single‐blinded . In the chokeberry intervention, the authors reported a significant increase in urinary excretion of potassium in the treatment group compared with control .…”

Section: Resultsmentioning

confidence: 99%

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The Effect of Berry‐Based Food Interventions on Markers of Cardiovascular and Metabolic Health: A Systematic Review of Randomized Controlled Trials

Heneghan

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Molecular Nutrition Food Res

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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The Effect of Berry‐Based Food Interventions on Markers of Cardiovascular and Metabolic Health: A Systematic Review of Randomized Controlled Trials

Heneghan

Kiely

Lyons

et al. 2018

Molecular Nutrition Food Res

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The emerging role of dark berry polyphenols in human health and nutrition

et al. 2022

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Dark berry fruits are one of the top 10 richest sources of dietary polyphenols and have been examined for their pharmacokinetic benefits in the human body related to absorption, digestion, metabolism, and excretion (ADME). With the expansion of the world wide web and rise of discretionary income in Europe and North America impacting the global food trade during the 21st century, several species of berries have become available for general consumption that may have previously been out of reach of the average consumer. Compared to their commercial counterparts, these berries contain many of the same polyphenols, and the possibility exists for the discovery of novel phenolic compounds that may affect the ADME process in a host-beneficial way.Several species have demonstrated antioxidant, antiobesogenic, antimicrobial, and anti-inflammatory properties through in vitro, animal studies, and human clinical trials. This review examines the available chemical compositions of several dark berries and their effect on the ADME process, their implication in host health effects, and the potential of these emerging species to suggest areas for future research.

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Profiling beneficial phytochemicals in a potato somatic hybrid for tuber peels processing: phenolic acids and anthocyanins composition

Jeddou

Kammoun

Hellström

et al. 2021

Food Science & Nutrition

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The purpose of this study was to characterize the peels of a CN1 somatic hybrid obtained from two dihaploid potato lines (Cardinal H14 and Nicola H1) in terms of the health‐promoting phenolic compounds (phenolic acids and anthocyanins). The CN1 hybrid is defined by a pink tuber skin color making it different from the light‐yellow‐skinned “Spunta,” which is the most commonly grown potato cultivar in Tunisia. Oven‐dried peel samples derived from CN1 hybrid and cv. Spunta were ground, and phenolic compounds were extracted with water or methanol for quantification. Lyophilized peels were used for the phenolic acid and anthocyanin analyses. Higher total quantities of phenolic compounds were recovered in methanol extracts compared with water extracts. A slightly higher concentration of phenolic acids (100 mg/100 g DW) was obtained in the lyophilized peels extract of CN1 hybrid than in the cv. Spunta corresponding sample (83 mg/100 g DW). The profiles of the chlorogenic acid isomers were almost identical in both of CN1 hybrid and cv. Spunta. Caffeic acid (CA) and three caffeoylquinic acids (CQAs): 3‐CQA, 4‐CQA, and 5‐CQA, were identified from both genotypes, 5‐CQA being the dominant form in both potatoes. Since the CN1 hybrid has a pink skin color, its anthocyanin profile was also determined. The anthocyanin quantity in the CN1 peels was 5.07 mg/100 g DW, involving six different anthocyanins that were identified within the extract, namely, Pelargonidin‐3‐rutinoside‐5‐glucoside, peonidin‐3‐rutinoside‐5‐glucoside, coumaroyl ester of pelargonidin‐3‐rutinoside‐5‐glucoside, coumaroyl ester of peonidin‐3‐rutinoside‐5‐glucoside, feruloyl ester of pelargonidin‐3‐rutinoside‐5‐glucoside, and feruloyl ester of peonidin‐3‐rutinoside‐5‐glucoside. These results suggest that the peel waste of CN1 somatic hybrid can be considered as a promising source of high‐value compounds for food industry.

show abstract

Consumption of chokeberry ( Aronia mitschurinii ) products modestly lowered blood pressure and reduced low-grade inflammation in patients with mildly elevated blood pressure

Cited by 78 publications

References 29 publications

The Effect of Berry‐Based Food Interventions on Markers of Cardiovascular and Metabolic Health: A Systematic Review of Randomized Controlled Trials

The Effect of Berry‐Based Food Interventions on Markers of Cardiovascular and Metabolic Health: A Systematic Review of Randomized Controlled Trials

The emerging role of dark berry polyphenols in human health and nutrition

Profiling beneficial phytochemicals in a potato somatic hybrid for tuber peels processing: phenolic acids and anthocyanins composition

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