Contact allergy to 8-methoxypsoralen

Weissmann, Irving; Wagner, G.; Plewig, Gerd

doi:10.1111/j.1365-2133.1980.tb05678.x

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1981

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Cited by 14 publications

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“…There are conflicting views about the possibility of photocontact sensitization. Many cases of contact allergy (28–31) and photocontact allergy (32–38) after exposure with furocoumarins, acquired during topical or systemic therapeutic procedures for eczema, psoriasis, vitiligo, and alopecia areata, have been reported in the literature. However, photoallergic reactions to psoralens resulting from contact with plants have rarely been described.…”

Section: Discussionmentioning

confidence: 99%

Photoallergic contact dermatitis to 8‐methoxypsoralen in Ficus carica

Bonamonte

Foti

Lionetti³

et al. 2010

Contact Dermatitis

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Allergic photoreactions induced by contact with plants containing coumarins are generally regarded as chance findings. This study has demonstrated that phytophoto allergic contact dermatitis resulting from furocoumarins is not an exceptional finding, and should be suspected in subjects with diffuse clinical manifestations in photo-exposed but also non-exposed sites. To differentiate allergic from toxic photoreactions, patch tests need to be performed with serial dilutions of furocoumarins. Histological analysis of a biopsy sample from a positive test site will reveal alterations compatible with a photoallergic contact dermatitis.

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Section: Discussionmentioning

confidence: 99%