Contrast Manipulation in MR Imaging of ShortT₂andT₂* Tissues

Magnetization transfer as a potential tool for the early detection of acute graft rejection after lung transplantation in mice

“…Without dedicated spin preparation, both sequences provide a proton‐density weighted contrast very similar to the information obtained from CT . Therefore, current MRI research focuses on dedicated spin‐preparation techniques for radial sampling strategies with specific contrast mechanisms, thereby increasing the potential for characterization of tissues showing fast signal decay . We showed that absolute differences in MTR were highest for an off‐resonance frequency of 1000 Hz.…”

“…With the development of ultrashort echo time and ZTE sequences using radial readout strategies, depiction of lung parenchyma at high field strengths became feasible. Without dedicated spin preparation, both sequences provide a proton‐density weighted contrast very similar to the information obtained from CT . Therefore, current MRI research focuses on dedicated spin‐preparation techniques for radial sampling strategies with specific contrast mechanisms, thereby increasing the potential for characterization of tissues showing fast signal decay .…”

ZTE imaging with long‐T2 suppression

“…Various approaches have been proposed to reduce the long‐ T 2 signal of water and/or fat , including subtraction of images acquired at longer TE or with short‐ T 2 tissues being suppressed , long‐ T 2 cancellation in balanced steady‐state free precession and magnetization preparation selectively targeting long‐ T 2 tissues. The latter is based on either saturation or inversion involving image combination or signal recovery as part of the preparation .…”