Controlled Anchoring of (Phenylureido)sulfonamide-Based Receptor Moieties: An Impact of Binding Site Multiplication on Complexation Properties

Abstract

The repetition of urea-based binding units within the receptor structure does not only lead to monomer properties multiplication. As confirmed by spectroscopic studies, UV-Vis and 1H-NMR in classical or competitive titration mode, the attachment to a carrier allocates the active moieties to mutual positions predetermining the function of the whole receptor molecule. Bivalent receptors form self-aggregates. Dendritic receptors with low dihydrogen phosphate loadings offer a cooperative complexation mode associated with a positive dendritic effect. In higher dihydrogen phosphate concentrations, the dendritic branches act independently and the binding mode changes to 1:1 anion: complexation site. Despite the anchoring, the dendritic receptors retain the superior efficiency and selectivity of a monomer, paving the way to recyclable receptors, desirable for economic and ecological reasons.

An Insight into Anion Extraction by Amphiphiles: Hydrophobic Microenvironments as a Requirement for the Extractant Selectivity

“…In addition, no solvent molecules participate in the lattice and the crystals contain large hydrophobic areas of the alkyl chains (Figure , blue). This is in contrast to the previously prepared analogous molecules in which the alkyl group on sulfonamide was the methyl group; these substances possess regions between the aromatic layers filled with DMSO solvent molecules.…”

Controllable Synthesis of Hybrid Dendrimers Composed of a Carbosilane Core and an Aromatic Shell: Does Size Matter?

“…First, carbosilane dendrimers were hydrosilylated with 3-chloropropyldimethylsilane followed by a replacement of the halogen for azide groups by sodium azide ( Schemes S1 and S2 , Figures S1–S7 , ESI). The complete substitution was for 24 h and 50 h for the first and second generation, respectively [ 17 , 18 , 19 ]. Synthesis of ethynyl-terminated HPB ( Scheme S3 , ESI) was carried out according to the procedures presented in [ 20 ].…”