Controlled release and corrosion protection by self-assembled colloidal particles electrodeposited onto magnesium alloys

Abstract

Self-assembled nanoparticles loaded with bioactive agents were electrodeposited to provide the magnesium alloy with controlled release and corrosion resistance properties.

Bi-directional controlled release of ibuprofen and Mg2+ from magnesium alloys coated by multifunctional composite

“…More importantly, compared with that of Mg/EP-ZnO/PCL-BRF2 and Mg/EP-ZnO/PCL-BRF3, the release of Mg 2+ ions from Mg/EP-ZnO/PCL-BRF1 is much lower. Because higher drug amounts can increase the hydrophily of the coating, as shown in Table 1, and more hydrophily of the coating can accelerate the degradation rate of the magnesium alloy [41]. However, these results clearly demonstrate that the deposited coating can provide a corrosion protection barrier for the underlying Mg alloy.…”

The application of nanomaterials in controlled drug delivery for bone regeneration

“…The nanocomplex could be a satisfactory controlled bone related bioactive agents delivery system candiadate. Moreover, the system significantly improved the cell attachment and proliferation, which could promisingly provide a suitable microenvironment for bone regeneration in vivo …”

“…Traditionally, many factors probably influence the toxicological response of nanomaterials, such as nano‐scale size, chemical composition, surface functionalisation and route of exposure on nanomaterial‐biological interactions . For example, when the size of silica nanoparticles reduces to 2 nm, the cytoxicity effect evidently enhances .…”

Electrophoretic deposition of colloidal particles on Mg with cytocompatibility, antibacterial performance, and corrosion resistance

“…In the previous study of our groups, polymer-based coatings were prepared from self-assembled colloidal particles through one-step electrophoretic deposition (EPD) process in ethanol [17,18]. EPD is a well-known, cost-effective coating formation process which requires only simple apparatus.…”