Controlled release on sand bed columns and biodegradability in soil of chitosan: Hydroxypropyl methylcellulose films

“…Its considerable swellability, hydrophilicity and non-ionic nature has paved the way for blending with various excipients, in the form of hydrogels, to achieve the controlled release of biological products. [109][110][111] In this case, HPMC was blended with different kinds of polymers, such as PVP, 112 CS, 113 EC, 114 gelatin, and xanthan gum 115 and in most cases, these blends showed remarkable controlled release activity. [116][117][118][119] Dharmalingam et al designed a combination of HPMC and NaCMC in the presence of citric acid (CA) as a crosslinking agent (citric acid crosslinked HPMC-NaCMC hydrogel films) in order to evaluate the controlled release of methylene blue and TCH for wound healing applications.…”

Section: Applications Of Cellulose and Its Blend Derivative In Cddssmentioning

confidence: 99%

<p>Burgeoning Polymer Nano Blends for Improved Controlled Drug Release: A Review</p>

Maghsoudi¹,

Shahraki²,

Rabiee³

et al. 2020

IJN

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With continual rapid developments in the biomedical field and understanding of the important mechanisms and pharmacokinetics of biological molecules, controlled drug delivery systems (CDDSs) have been at the forefront over conventional drug delivery systems. Over the past several years, scientists have placed boundless energy and time into exploiting a wide variety of excipients, particularly diverse polymers, both natural and synthetic. More recently, the development of nano polymer blends has achieved noteworthy attention due to their amazing properties, such as biocompatibility, biodegradability and more importantly, their pivotal role in controlled and sustained drug release in vitro and in vivo. These compounds come with a number of effective benefits for improving problems of targeted or controlled drug and gene delivery systems; thus, they have been extensively used in medical and pharmaceutical applications. Additionally, they are quite attractive for wound dressings, textiles, tissue engineering, and biomedical prostheses. In this sense, some important and workable natural polymers (namely, chitosan (CS), starch and cellulose) and some applicable synthetic ones (such as poly-lactic-co-glycolic acid (PLGA), poly(lactic acid) (PLA) and poly-glycolic acid (PGA)) have played an indispensable role over the last two decades for their therapeutic effects owing to their appealing and renewable biological properties. According to our data, this is the first review article highlighting CDDSs composed of diverse natural and synthetic nano biopolymers, blended for biological purposes, mostly over the past five years; other reviews have just briefly mentioned the use of such blended polymers. We, additionally, try to make comparisons between various nano blending systems in terms of improved sustained and controlled drug release behavior.

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“…13 Therefore, a major research direction is to research coating materials, which not only have better efficacy in slow release of nutrients but also have a low cost and are environment-friendly. 14,15 Degradable water-soluble high molecular weight polymer and natural product are good choices for coating materials, such as cellulose, 16 chitosan, [17][18][19] starch, [20][21][22] polyvinyl alcohol, [23][24][25] polyacrylamide, 26 sodium alginate, 27 lignin. 28,29 These coating materials are environmentally friendly and have a low cost, but their slow release effects are affected by their high water absorbing quality.…”

Section: Introductionmentioning

confidence: 99%

Waterborne polymer modified with zeolite for environment‐friendly slow‐release coated urea

Han

Chen

Xie

et al. 2023

J of Applied Polymer Sci

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In order to improve the slow‐release effectiveness of waterborne polymer coated fertilizers, an environment‐friendly coated urea was developed by zeolite and waterborne polymer of starch soluble, polyvinyl alcohol, sodium carboxymethyl cellulose, and chitosan. The properties of different mesh and content of zeolite on the membranes and the slow‐release property of coated urea were investigated. Zeolite decreased water vapor, ammonium permeability and porosity of waterborne polymer with an increased ammonium adsorption, and contributed to improve the slow‐release effectiveness of coated urea. In particular, zeolite‐modified waterborne polymer of 200 mesh and 3% content had best effect with 10.8%, 16.5%, and 59.8% decrease of water absorption capacity, water vapor permeability and ammonium permeability, 17.7% increase of water contact angles. Zeolite‐modified waterborne polymer coated urea for the coating contents of 7% had the best effect on the nutrient accumulate release rate. Therefore, zeolite‐modified waterborne polymers have potential to improve the slow‐release effectiveness of coated urea.

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Controlled release on sand bed columns and biodegradability in soil of chitosan: Hydroxypropyl methylcellulose films

Cited by 8 publications

References 53 publications

Chitosan-based delivery systems for plants: A brief overview of recent advances and future directions

Chitosan-based delivery systems for plants: A brief overview of recent advances and future directions

<p>Burgeoning Polymer Nano Blends for Improved Controlled Drug Release: A Review</p>

Waterborne polymer modified with zeolite for environment‐friendly slow‐release coated urea

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