Controlled three-dimensional polystyrene micro- and nano-structures fabricated by three-dimensional electrospinning

Vong, Michel; Speirs, Ewan; Klomkliang, Chanakan; Akinwumi, Ibukun; Nuansing, Wiwat; Radacsi, Norbert

doi:10.1039/c7ra13278f

Cited by 38 publications

(61 citation statements)

References 69 publications

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“…It is also widely used in medical diagnosis and drug delivery as they can immobilize the recognition element or active pharmaceutical ingredient due to the large surface area and porosity [15,18,19]. Recently, electrospinning has been also used for replica molding and producing three-dimensional scaffolds [20,21].…”

Section: Introductionmentioning

confidence: 99%

Low-cost FDM 3D-printed modular electrospray/electrospinning setup for biomedical applications

2020

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Here, we report on the inexpensive fabrication of an electrospray/electrospinning setup by fused deposition modelling (FDM) 3D printing and provide the files and parameters needed to print this versatile device. Both electrospray and electrospinning technologies are widely used for pharmaceutical, healthcare and bioengineering applications. The setup was designed to be modular, thus its parts can be exchanged easily. The design provides a safe setup, ensuring that the users are not exposed to the high voltage parts of the setup. PLA, PVA, and a thermoplastic elastomer filament were used for the 3D printing. The filament cost was $100 USD and the rig was printed in 6 days. An Ultimaker 3 FDM 3D printer was used with dual print heads, and the PVA was used as a water-soluble support structure. The end part of the setup had several gas channels, allowing a uniform gas flowing against the direction of the nanoparticles/nanofibers, enhancing the drying process by enhancing the evaporation rate. The setup was tested in both electrospray and electrospinning modes successfully. Both the .sldprt and .stl files are provided for free download.

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Section: Introductionmentioning

confidence: 99%

Low-cost FDM 3D-printed modular electrospray/electrospinning setup for biomedical applications

2020

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“…Good general agreement can be seen between the predicted and measured fiber diameters. The rate of increase of fiber diameter with polymer concentration is in qualitative agreement with the experimental work of …”

Section: Resultsmentioning

confidence: 99%

Empirical model to simulate morphology of electrospun polycaprolactone mats

Yousefi

Tang

Tafreshi

et al. 2019

J of Applied Polymer Sci

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This work is the first to report a study aimed at generating 3D virtual geometries that represent the microstructure of an electrospun fibrous mat comprised curly fibers. Polycaprolactone (PCL) mats are considered in our study as an example of such fibrous structures. We started with simulating the formation of PCL filaments and observed good agreement between the predicted and measured fiber diameters. In the absence of quantitative information about the shape of a curly PCL fiber, we treated these fibers as arrays of beads arranged on epitrochoid profiles. We then used the fiber deposition diameter and velocity in a mass-spring-damper (MSD) model to generate 3D fibrous geometries comprised hundreds of such curly fibers. The damping and spring constants in the MSD model were obtained through calibration with experimental data reported for single electrospun PCL nanofibers. The size of the epitrochoid-like fibers was obtained empirically through matching the average thickness of the resulting mats with those measured experimentally. With the calibrated code, we studied the effects of electrospinning conditions on the porosity of PCL nanofiber mats. It was found that increasing the voltage or decreasing the needle-to-collector distance results in PCL mats with thicker fibers, and consequently, lower porosities.

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“…104 It is also possible to directly combine 3D printing and electrospinning to generate 3D structures. 93,104,105 The interested reader is directed to two recent reviews for more information. 93,104 While ES scaffolds with porous structures can be desirable, scaffolds with densely packed fibres are also beneficial in some scenarios because they effectively resist cell infiltration and tissue ingrowth.…”

Section: Tissue Engineeringmentioning

confidence: 99%

Electrospinning for healthcare: recent advancements

Dziemidowicz

Sang

et al. 2021

J. Mater. Chem. B

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Controlled three-dimensional polystyrene micro- and nano-structures fabricated by three-dimensional electrospinning

Abstract: The combination of electrospinning and extrusion based 3D printing opens new pathways for micro- and nanofabrication in a wide range of applications. The fast production of a highly stable self-standing polystyrene 3D structure is demonstrated.

Cited by 38 publications

References 69 publications

Low-cost FDM 3D-printed modular electrospray/electrospinning setup for biomedical applications

Low-cost FDM 3D-printed modular electrospray/electrospinning setup for biomedical applications

Empirical model to simulate morphology of electrospun polycaprolactone mats

Electrospinning for healthcare: recent advancements

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