Coordination of oro-pharyngeal food transport during chewing and respiratory phase

Matsuo, Koichiro; Palmer, Jeffrey B.

doi:10.1016/j.physbeh.2015.01.035

Cited by 17 publications

(16 citation statements)

References 20 publications

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“…Review of the entire content of the 54 articles resulted in 37 studies that met inclusion criterion and were recommended for inclusion (see Figure 1). Data were extracted from 37 articles (Ayuse et al, 2006;Balasubramanium & Bhat, 2012;Boden et al, 2009;Dozier et al, 2006;Fontecave-Jallon & Baconnier, 2016;Gürgör et al, 2013;Hårdemark Cedborg et al, 2010Hirst et al, 2002;Hiss et al, 2001;Kelly et al, 2006;Kelly, Huckabee, Jones, & Carroll, 2007;Kelly, Huckabee, Jones, & Frampton, 2007;Klahn & Perlman, 1999;Lederle et al, 2012;Leslie et al, 2005;Martin et al, 1994;Martin-Harris et al, 2005, 2003Matsuo & Palmer, 2015;McFarland & Lund, 1995;McFarland et al, 1994McFarland et al, , 2016Nilsson et al, 1996;Nishino et al, 1985;Palmer & Hiiemae, 2003;Paydarfar et al, 1995;Perlman et al, 2005;Pinto et al, 2017;Preiksaitis et al, 1992;Preiksaitis & Mills, 1996;Smith et al, 1989;Wang et al, 2016;Wang, Cheng, et al, 2015;K. Wheeler Hegland et al, 2011;K.…”

Section: Resultsmentioning

confidence: 99%

Respiratory Phase and Lung Volume Patterns During Swallowing in Healthy Adults: A Systematic Review and Meta-Analysis

Hopkins-Rossabi

Curtis

Temenak

et al. 2019

J Speech Lang Hear Res

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Section: Resultsmentioning

confidence: 99%

Respiratory Phase and Lung Volume Patterns During Swallowing in Healthy Adults: A Systematic Review and Meta-Analysis

Hopkins-Rossabi

Curtis

Temenak

et al. 2019

J Speech Lang Hear Res

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“…Therefore, we infer that Sound I corresponds to the closure of the nasopharynx. The bolus is usually located in the oral cavity, but it can be in the oropharynx or the hypopharynx in the case of the chew–swallow complex behavior [21]. (2) Sound II usually occurs 200–250 ms after the onset of the pharyngeal swallow.…”

Section: Discussionmentioning

confidence: 99%

A noninvasive swallowing measurement system using a combination of respiratory flow, swallowing sound, and laryngeal motion

Yagi

Nagami

Lin

et al. 2016

Med Biol Eng Comput

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The assessment of swallowing function is important for the prevention of aspiration pneumonia. We developed a new swallowing monitoring system that uses respiratory flow, swallowing sound, and laryngeal motion. We applied this device to 11 healthy volunteers and 10 patients with dysphagia. Videofluoroscopy (VF) was conducted simultaneously with swallowing monitoring using our device. We measured laryngeal rising time (LRT), the time required for the larynx to elevate to the highest position, and laryngeal activation duration (LAD), the duration between the onset of rapid laryngeal elevation and the time when the larynx returned to the lowest position. In addition, we evaluated the coordination between swallowing and breathing. We found that LAD was correlated with a VF-derived parameter, pharyngeal response duration (PRD) in healthy subjects (LAD: 959 ± 259 ms vs. PRD: 1062 ± 149 ms, r = 0.60); however, this correlation was not found in the dysphagia patients. LRT was significantly prolonged in patients (healthy subjects: 320 ± 175 ms vs. patients: 465 ± 295 ms, P < 0.001, t test). Furthermore, frequency of swallowing immediately after inspiration was significantly increased in patients. Therefore, the new device may facilitate the assessment of some aspects of swallowing dysfunction.

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“…E, Scatter plots show IPSC frequency was significantly greater in WT (5.82 6 0.8 Hz) versus LgDel rMNs (2.70 6 0.7 Hz, unpaired Students' t test, df = 28, p = 0.0099). For all graphs, data expressed as mean 6 SEM; statistical comparisons are noted as pp , 0.05, ppp , 0.01. traffic (Matsuo and Palmer, 2015;Maynard et al, 2020). Accordingly, we assessed the putative rhythmic respiratory activity which can be confined within the thick neonatal slices (Wang et al, 2005) on protruder and retractor XII MN firing (Fig.…”

Section: Phasic Cnxii Mn Activity During Inspiratory-related Burstsmentioning

confidence: 99%

“…Retractor and protruder MN activity during respiration has been analyzed exclusively in adults. To our knowledge, there is no information on these CNXII MN classes in neonates, despite their likely contribution to the critical suck/breathe/swallow sequence (Matsuo and Palmer, 2015). The disruption of cranial nerve development in LgDel from midgestation onward suggests that perinatal cranial nerve dysfunction, including that of CNXII MNs, may be an important contributor to dysphagia pathology because of 22q11.2 deletion (Vitelli et al, 2002;LaMantia et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Disrupted Coordination of Hypoglossal Motor Control in a Mouse Model of Pediatric Dysphagia in DiGeorge/22q11.2 Deletion Syndrome

Wang

Popratiloff

Motahari

et al. 2020

eNeuro

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We asked whether the physiological and morphologic properties of hypoglossal motor neurons (CNXII MNs) that innervate protruder or retractor tongue muscles are disrupted in neonatal LgDel mice that carry a heterozygous deletion parallel to that associated with DiGeorge/22q11.2 deletion syndrome (22q11.2DS). Disrupted coordination of tongue movement in LgDel mouse pups may contribute to suckling, feeding, and swallowing (S/F/S) disruptions that parallel pediatric dysphagia in infants and toddlers with 22q11.2DS. Using an in vitro rhythmically active medullary slice preparation, we found spontaneous firing as well as IPSC frequency differed significantly in neonatal LgDel versus wild-type (WT) protruder and retractor CNXII MNs that were identified by retrograde tracing from their target muscles. In response to respiration-related activity, initiation and decay of transiently increased firing in WT protruder MNs is delayed in LgDel, accompanied by altered excitatory/inhibitory (E/I) balance. In addition, LgDel retractor MNs have a transient increase in firing with diminished IPSC frequency that is not seen in WT. There were no significant differences in cell body volume of either XII class in WT and LgDel. Sholl analysis showed the total numbers of dendritic intersections (at 50-and 90-mm radii from the cell soma) were significantly greater for LgDel versus WT retractor MNs. Thus, the physiological, synaptic and cellular properties of distinct classes of CNXII MNs that coordinate tongue movement in neonatal WT mice are altered in LgDel. Such changes could contribute to sub-optimal coordination of S/F/S that underlies pediatric dysphagia in 22q11.2DS.

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Coordination of oro-pharyngeal food transport during chewing and respiratory phase

Cited by 17 publications

References 20 publications

Respiratory Phase and Lung Volume Patterns During Swallowing in Healthy Adults: A Systematic Review and Meta-Analysis

Respiratory Phase and Lung Volume Patterns During Swallowing in Healthy Adults: A Systematic Review and Meta-Analysis

A noninvasive swallowing measurement system using a combination of respiratory flow, swallowing sound, and laryngeal motion

Disrupted Coordination of Hypoglossal Motor Control in a Mouse Model of Pediatric Dysphagia in DiGeorge/22q11.2 Deletion Syndrome

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