Copper-Free Sonogashira coupling in water with an amphiphilic resin-supported palladium complex

Green synthesis of Pd/Fe 3 O 4 nanoparticles using Euphorbia condylocarpa M. bieb root extract and their catalytic applications as magnetically recoverable and stable recyclable catalysts for the phosphine-free Sonogashira and Suzuki coupling reactions

“…The solvent was evaporated at reduced pressure, and the residue was subjected to gel permeation chromatography to afford pure products. All the products are known compounds and the spectral data and melting points were identical to those reported in the literature [30][31][32][33].…”

Polymers for Green C–C Couplings

“…The same system has been applied to the selective monoarylation of dibromoaryls by Suzuki coupling [80] and also to the Cu-free Sonogashira reaction. [81] The asymmetric Suzuki coupling in water to afford binaphthyls and other arylnaphthyls enantioselectively was carried out with chiral PS-PEG phosphane 20 ( Figure 6) mixed in situ with Pd(OAc) 2 ; [82] this catalyst system can be recycled. The Suzuki coupling of aryl chlorides with a PS-PEG-supported analogue of ligand 3 (R = Cy, Figure 1) in a toluene/EtOH/H 2 O solvent mixture has been reported.…”

Tetradentate Palladium(II) Salophen Complexes: Synthesis, Characterization and Catalytic Activities in Copper-Free Sonogashira Coupling Reaction

“…Palladium, the main catalyst, has been used widely and a plethora of research activities had been performed to tune its catalytic activity by varying the ligand environment. This includes the gradual replacement of phosphine-based ligands to nitrogen-based ligands such as Schiff bases as the former are unstable towards air, moisture and temperature, highly toxic and cost-ineffective [5]. The sensitivity of phosphine complexes may contribute to P-C bond degradation especially when the reaction is carried out at elevated temperatures lead to decomposition of the catalyst which could intensely affect conversion and selectivity [6].…”