Coriandrin, a novel highly photoactive compound isolated from Coriandrum sativum

Ceska, Oldriska; Chaudhary, Sunil Kumar; Warrington, P. J.; Ashwood-Smith, M.J.; Bushnell, Gordon W.; Poultont, G.A.

doi:10.1016/0031-9422(88)80101-8

Cited by 43 publications

(38 citation statements)

References 19 publications

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“…[14][15][16] Very little work has been reported on the chemistry 17,18 and activity [19][20][21][22] of the seed volatile oil of this plant, or on its oleoresin. [23][24][25] In continuation of our research programme on essential oils, 19,[26][27][28][29] investigations of the chemical, antifungal, antioxidant and sproutsuppressant activities (SSA) of the seed essential oil and its oleoresin have been undertaken and the results are reported in this communication.…”

Section: Introductionmentioning

confidence: 98%

Studies on essential oils, Part 41. Chemical composition, antifungal, antioxidant and sprout suppressant activities of coriander (Coriandrum sativum) essential oil and its oleoresin

Singh

Maurya

Lampasona

et al. 2006

Flavour & Fragrance J

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Gas chromatography-mass spectrometry (GC-MS) analysis of the seed oil of coriander (Coriandrum sativum) showed the presence of 52 components, accounting for 98.45% of the total oil. The major components were linalool (75.30%), geranyl acetate (8.12%) and α α α α α-pinene (4.09%). Its oleoresin showed the presence of 28 components. Oleic acid (36.52%), linoleic acid (33.2%) and palmitic acid (11.05%) were the major components. The antifungal activities of coriander oil and its oleoresin against eight fungi were evaluated using the inverted petriplate and food poison techniques. Using the inverted petriplate method, the essential oil was found to be highly active against Curvularia palliscens, Fusarium oxysporum, Fusarium moniliforme and Aspergillus terreus. In the case of the oleoresin, more than 50% mycelial zone inhibition was obtained for the fungi Fusarium oxysporum, Aspergillus niger and Aspergillus terreus. Using the food poison technique, the essential oil showed 100% inhibition on the growth of A. terreus, A. niger, F. graminearum and F. oxysporum, whereas its oleoresin showed weaker fungitoxic activity, exhibiting 100% inhibition on the growth of F. oxysporum only. The oleoresin had a better antioxidant activity for sunflower oil than essential oil and synthetic antioxidants, BHA and BHT. The oil was also found to exert strong sprout suppressant activity (SSA) for potatoes. Copyright

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Section: Introductionmentioning

confidence: 98%

Studies on essential oils, Part 41. Chemical composition, antifungal, antioxidant and sprout suppressant activities of coriander (Coriandrum sativum) essential oil and its oleoresin

Singh

Maurya

Lampasona

et al. 2006

Flavour & Fragrance J

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“…In addition, in certain countries (e.g., China, India, and Mexico) and in certain geographical areas of the United States (e.g., the Southwest) fresh coriander leaves (also known as cilantro or Chinese parsley) are used extensively in soups, chutneys, sauces, flavoring curries, and even in wine. Recently, several furanoisocoumarins (e.g., coriandrin, and dihydrocoriandrin) have been identified from fresh coriander [Ceska et al, 1988;Ashwood-Smith et al, 1989]. Humans can be exposed to these compounds regularly in the diet.…”

Section: Introductionmentioning

confidence: 98%

Antigenotoxic activity of naturally occurring furanocoumarins

Marumoto

Oda

Miyazawa

2011

Environ. Mol. Mutagen.

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This study was designed to investigate the antigenotoxic effects of a series of naturally occurring furanocoumarins (NOFs) including isoimperatorin, imperatorin, (+)-oxypeucedanin, (+)-byakangelicol, and (+)-byakangelicine on antigenotoxic activities against genotoxicity induced by carcinogens [furylfuramide and N-methyl-N'-nitro-N-nitrosoguanidine], and procarcinogens 2-[2-(acetylamino)-4-amino-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H-benzotriazole (PBTA-4) and 2-amino-3,4-dimethyl-3H-imidazo-[4,5-f] quinoline (MeIQ)] to genotoxic metabolites catalyzed by rat S9 or rat and human recombinant cytochrome P450 (CYP) 1As by using the umu test based on SOS response. Five different NOFs, which were found in the human diets, strongly inhibited the umuC induction by procarcinogens, but did not be affected by carcinogens. Notably, isoimperatorin and (+)-byakangelicol were found to be potent inhibitors on the metabolic activation of PBTA-4 and MeIQ to genotoxic metabolites catalyzed by rat and human CYP1A1, or rat and human CYP1A2, respectively. In addition, to elucidate the mechanism of their antigenotoxic effects against procarcinogens, the effects of NOFs on rat and human CYP1A1- or rat and human CYP1A2-related enzyme activities of 7-ethoxyresorufin-O-deethylase (EROD) were also investigated. Reduction of the EROD activities by some of the NOFs with IC(50) values of 0.23-20.64 μM was found to be due to strong inhibition of CYP1A1 and CYP1A2 dependent monooxygenases. Furthermore, the mechanism of inhibitions by NOFs on human CYP1A1 and CYP1A2 was analyzed by means of Dixon plots plus Cornish-Bowden plots. The kinetic studies of inhibition types revealed that these compounds inhibited the human CYP1A1 and CYP1A2 a variety of modes rather than by a uniform one. Moreover, experiments with a two-stage incubation indicated that NOFs, except for imperatorin, inhibited human CYP1A1 in a mechanism-based manner, but directly inhibited human CYP1A2. This data suggest that certain NOFs, to which humans are exposed in the diet, may be capable of affecting the metabolic activation of procarcinogens due to inhibitions of CYP1A1 and CYP1A2 enzymes.

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“…The fruit of coriander contains anethol, borneol, bornyl acetate, camphor, camphene, carvone, cineole, cymene, coriandrin, dihydrocoriandrin (Ceska et al, 1988), coriandrone A, coriandrone B (Baba et al, 1991), coriandrones C-E (Taniguchi et al, 1996), phydroxybenzoic acid, limonene, linoleic acid, myrcene, myristic acid, myristicin, oleic acid, palmitic acid, ␣-phellandrene, ␤-phellandrene, ␣-terpinene, ␥-terpinene, terpineol, umbelliferone, etc. (Duke, 1992), ␣-pinene, ␤-pinene, quercetin, rutin, sitosterol and stigmasterol (Zlatanov and Ivanov, 1995).…”

Section: Introductionmentioning

confidence: 99%

Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities

Jabeen

Bashir

Lyoussi

et al. 2009

Journal of Ethnopharmacology

109

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Coriandrin, a novel highly photoactive compound isolated from Coriandrum sativum

Cited by 43 publications

References 19 publications

Studies on essential oils, Part 41. Chemical composition, antifungal, antioxidant and sprout suppressant activities of coriander (Coriandrum sativum) essential oil and its oleoresin

Studies on essential oils, Part 41. Chemical composition, antifungal, antioxidant and sprout suppressant activities of coriander (Coriandrum sativum) essential oil and its oleoresin

Antigenotoxic activity of naturally occurring furanocoumarins

Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities

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