Corneal tolerance to micronised mineral pigments for keratopigmentation

Amesty, María; Alió, Jorge L.; Rodrı́guez, Alejandra

doi:10.1136/bjophthalmol-2014-305611

Cited by 19 publications

(10 citation statements)

References 16 publications

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“…Subsequently, micronized mineral pigments were produced and first used in the practice of KTP in 2010 (16). The histopathological tolerance, immune reactivity, and local toxicity of these pigments have been discussed in the literature (8). Reducing the size of the particles through micronization is an advantage over natural pigments in terms of the chance of developing foreign body reaction (9,10,20).…”

Section: Discussionmentioning

confidence: 99%

“…However, for various reasons, KTP did not become commonplace. A satisfactory appearance could require several combinations, and fading of the color was a problem (8).…”

Section: Introductionmentioning

confidence: 99%

“…KTP could be a very beneficial option, as it is a less invasive operation, has a high patient satisfaction rate, a smaller cost, and potential accessibility (13). In order to reduce the potential effects of a sensation of a foreign body and activation of the inflammatory response, micronized mineral pigments with smaller particles are now preferred (8). The early intrastromal techniques could not eliminate the possibility of permanent superficial corneal opacity (11).…”

Section: Introductionmentioning

confidence: 99%

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Keratopigmentation: Is it a miracle or an adventure?

Karslıoğlu¹

2020

Beyoglu Eye J

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This study is an analysis of the cosmetic and functional results of patients who underwent keratopigmentation (KTP). Methods: Sixteen eyes of 16 patients, 7 females (43.75%) and 9 males (56.25%) were included in the study. Intrastromal and superficial manual KTP were performed under general anesthesia. Patients with no light perception or with only light perception but total corneal opacification, prosthetic contact lens intolerance, or unwillingness to use a contact lens were studied. The main outcomes were postoperative patient's satisfaction, cosmetic results, pigment stabilization and surgical complications. A grading system (0-5 points) was used to assess patient satisfaction and the cosmetic results. Results: The mean age of the patients was 30.5±12.06 years (range: 16-53 years). Black pigment was used in 10 patients (62.5%), a brownish color in 5 patients (31.25%) and a greenish, yellow, blue, and black color pigmentation was used for 1 patient (6.25%). The mean follow-up was 29.31±15.45 months (range: 8-52 months). In 2 of 16 patients, mild to moderate pigment loss was seen 12 months after the surgery and superficial KTP was repeated. Minimal pigment loss was seen in 5 patients, but the cosmetic results were satisfactory and no secondary surgical procedure was required. Pigment leakage underneath the conjunctiva was seen in only 1 patient. Otherwise, there were no complications associated with keratopigmentation. The postoperative mean patient satisfaction score was 4.18±0.75 points (range: 3-5 points). Conclusion: KTP is a safe surgical procedure that is easy to learn and perform, does not require expensive materials, and avoids more extensive and invasive reconstructive ocular procedures. Corneal KTP may have a great impact on future ophthalmic surgical practice from both therapeutic and cosmetic perspectives.

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Section: Discussionmentioning

confidence: 99%

“…However, for various reasons, KTP did not become commonplace. A satisfactory appearance could require several combinations, and fading of the color was a problem (8).…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Keratopigmentation: Is it a miracle or an adventure?

Karslıoğlu¹

2020

Beyoglu Eye J

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“…Thus pigmented corneas showed a good cosmetic appearance without signs of ocular toxicity. [14][15][16][17] With the main future perspective of improving customization of colors and creating guidelines for standardization of surgical procedure and techniques, we believe that KTP will develop more potentiality in terms of cosmetic use of this novel surgical technique.…”

Section: Discussionmentioning

confidence: 99%

Keratopigmentation to Change the Apparent Color of the Human Eye

Alió¹,

Rodrı́guez

Bahrawy³

et al. 2016

Cornea

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“…A number of studies have been published on the potential use of KTP for improving the cosmetic effect in patients with leucomas with an excellent result and patient satisfaction. Despite this fact, experiences with corneal tattooing are limited worldwide, which to a substantial extent is a consequence of the unavailability of commercially produced pigments (2,3,4,8). However, for patients with an unstable structure of the corneal surface, for example with active angiogenesis, recurrent erosions of the epithelium and irregularities of the corneal surface, corneal tattooing is usually unsuitable (6).…”

Section: Case Reportmentioning

confidence: 99%

Keratopigmentation (Corneal Tattoo) - Our First Experience

Žiak¹,

Kapitánová

Halička

et al. 2018

CSO

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Introduction: Keratopigmentation or corneal tattooing represents an unique cosmetic solution for corneal leucomas and also for other pathological changes affecting cornea or iris. Procedure is based on pigment insertion into the corneal stroma. Goal is to improve the appearance of the affected eye. These days are most frequently used tattoo kits with different sterilised inks made primary for skin tattooing. As a new possibility there are also available biocompatible micronized mineral pigments. Methods: Authors will introduce four case reports of four patients with corneal leucomas, who wanted to undergo the corneal tattooing to improve the cosmetic appearance of their blind eyes. Authors decided for keratopigmentation with an use of inks intended primary for skin tattooing. Results: In all four patients was the final appearance of tattooed cornea more than satisfying. Postoperative examination didn´t detect diffusion, fading, colour changes of the pigments. No complications such as toxic or immune reaction due to the pigment were recorded. All four patients were subjectively fully satisfied with the cosmetic result of the keratopigmentation. Conclusion: Based on the first experience authors consider keratopigmentation to be a safe and relatively uncomplicated surgical method. Corneal tattooing is also quite cheap, does not require patient´s hospitalization and postoperative reconvalescence in usually short term.

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Corneal tolerance to micronised mineral pigments for keratopigmentation

Abstract: Micronised mineral pigments could be a valid alternative treatment for cosmetic keratopigmentation. The intralamellar keratopigmentation technique presented good cosmetic appearance without adverse effects in the eyes treated.

Cited by 19 publications

References 16 publications

Keratopigmentation: Is it a miracle or an adventure?

Keratopigmentation: Is it a miracle or an adventure?

Keratopigmentation to Change the Apparent Color of the Human Eye

Keratopigmentation (Corneal Tattoo) - Our First Experience

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