Correction of motion artifacts and scanning beam distortions in 3D ophthalmic optical coherence tomography imaging

Zawadzki, Robert J.; Fuller, Alfred R.; Choi, Stacey S.; Wiley, David F.; Hamann, Bernd; Werner, John S.

doi:10.1117/12.701524

Cited by 44 publications

(48 citation statements)

References 7 publications

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“…Moreover, we experienced that, for our setup, best image quality can be achieved when the pivot point of the imaging beam is located approximately at the nodal point of the eye, close to the posterior surface of the crystalline lens. Axial alignment to the nodal point also reduces retinal curvature in the OCT images [64]. It should be emphasized that this alignment strategy is different to the common approach, where the axial position of the pivot point is placed close to the pupil, in order to avoid clipping of the extreme rays [64,65].…”

Section: Oct Imaging Setup Data Acquisition and Processingmentioning

confidence: 99%

Multi-MHz retinal OCT

Klein

Wieser

Reznicek

et al. 2013

Biomed. Opt. Express

201

124

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Abstract:We analyze the benefits and problems of in vivo optical coherence tomography (OCT) imaging of the human retina at A-scan rates in excess of 1 MHz, using a 1050 nm Fourier-domain mode-locked (FDML) laser. Different scanning strategies enabled by MHz OCT line rates are investigated, and a simple multi-volume data processing approach is presented. In-vivo OCT of the human ocular fundus is performed at different axial scan rates of up to 6.7 MHz. High quality non-mydriatic retinal imaging over an ultra-wide field is achieved by a combination of several key improvements compared to previous setups. For the FDML laser, long coherence lengths and 72 nm wavelength tuning range are achieved using a chirped fiber Bragg grating in a laser cavity at 419.1 kHz fundamental tuning rate. Very large data sets can be acquired with sustained data transfer from the data acquisition card to host computer memory, enabling high-quality averaging of many frames and of multiple aligned data sets. Three imaging modes are investigated: Alignment and averaging of 24 data sets at 1.68 MHz axial line rate, ultra-dense transverse sampling at 3.35 MHz line rate, and dual-beam imaging with two laser spots on the retina at an effective line rate of 6.7 MHz. 58. R. Huber, D. C. Adler, V. J. Srinivasan, and J. G. Fujimoto, "Fourier domain mode locking at 1050 nm for ultrahigh-speed optical coherence tomography of the human retina at 236,000 axial scans per second," Opt. Lett. ©2013 Optical Society of America

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Section: Oct Imaging Setup Data Acquisition and Processingmentioning

confidence: 99%

Multi-MHz retinal OCT

Klein

Wieser

Reznicek

et al. 2013

Biomed. Opt. Express

201

124

View full text Add to dashboard Cite

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“…To justify the effectiveness of the proposed method, we compare the registration results with and without motion correction. In addition, we have also compared our method with the case where every B-scan is aligned with precedent scan in [3]. Table 1 summarizes the RMSE, MAE, median error and the success rate in registration.…”

Section: Resultsmentioning

confidence: 99%

“…Therefore, some software algorithms are proposed for motion correction. Zawadzki et al [3] use autocorrelation method to align stack of B-scan slides. In the algorithm, each B-scan is used as the reference with respect to which the next B-scan is aligned.…”

Section: Introductionmentioning

confidence: 99%

“…The horizontal movement in y-axis introduces the mis-matched blood vessels and disc boundaries in the en face image and makes the registration between OCT en face image and image from other modality a difficult problem. A straightforward way is to register each B-scan to its precedent scan as in [3]. Taking B i as a reference, each B-scan B i is aligned to its precedent B-scan B i−1 such that their difference is minimized or the correlation is maximized.…”

Section: Introductionmentioning

confidence: 99%

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Motion Correction in Optical Coherence Tomography for Multi-modality Retinal Image Registration

Cheng

Lee

et al. 2016

Proceedings of the Ophthalmic Medical Image Analysis Third International Workshop

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Abstract. Optical coherence tomography (OCT) is a recently developed non-invasive imaging modality, which is often used in ophthalmology. Because of the sequential scanning in form of A-scans, OCT suffers from the inevitable eye movement. This often leads to mis-alignment especially among consecutive B-scans, which affects the analysis and processing of the data such as the registration of the OCT en face image to color fundus image. In this paper, we propose a novel method to correct the mis-alignment among consecutive B-scans to improve the accuracy in multi-modality retinal image registration. In the method, we propose to compute decorrelation from overlapping B-scans and to detect the eye movement. Then, the B-scans with eye movement will be re-aligned to its precedent scans while the rest of B-scans without eye movement are untouched. Our experiments results show that the proposed method improves the accuracy and success rate in the registration to color fundus images.

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“…The distortion due to a 2-axis MEMS mirror typically has a fan shape while the distortion generated by galvanometers is shaped as a pincushion. Most distortion correction algorithms are based on a point-to-point mapping method [9][10][11]. Although this method is universal, it needs a complicated mapping process and can only be applied after the original interferogram data are converted to the structural image [12].…”

Section: Introductionmentioning

confidence: 99%

Correction of image distortions in endoscopic optical coherence tomography based on two-axis scanning MEMS mirrors

Wang

Peng²,

Samuelson

et al. 2013

Biomed. Opt. Express

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A two-axis scanning microelectromechanical (MEMS) mirror enables an optical coherence tomography (OCT) system to perform threedimensional endoscopic imaging due to its fast scan speed and small size. However, the radial scan from the MEMS mirror causes various distortions in OCT images, namely spherical, fan-shaped and keystone distortions. In this paper, a new method is proposed to correct all of three distortions presented in OCT systems based on two-axis MEMS scanning mirrors. The spherical distortion is corrected first by directly manipulating the original spectral interferograms in the phase domain, followed by Fourier transform and three-dimensional geometrical transformation for correcting the other two types of distortions. OCT imaging experiments on a paper with square ink printed arrays and a glass tube filled with milk have been used to validate the proposed method. Distortions in OCT images of flat or curved surfaces can all be effectively removed.

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Correction of motion artifacts and scanning beam distortions in 3D ophthalmic optical coherence tomography imaging

Cited by 44 publications

References 7 publications

Multi-MHz retinal OCT

Multi-MHz retinal OCT

Motion Correction in Optical Coherence Tomography for Multi-modality Retinal Image Registration

Correction of image distortions in endoscopic optical coherence tomography based on two-axis scanning MEMS mirrors

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