2013
DOI: 10.1186/1471-2458-13-603
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Correlation between metabolic syndrome and knee osteoarthritis: data from the Korean National Health and Nutrition Examination Survey (KNHANES)

Abstract: BackgroundThis study was designed to investigate the correlations of knee osteoarthritis (OA) with metabolic syndrome (MetS) and MetS parameters in Korean subjects.MethodsThis study included data from 270 subjects with knee OA and 1964 control subjects with a mean age of 54.56 (SD 11.53) years taken from the Korean National Health and Nutritional Examination Survey (KNHANES) 2008. Multivariate logistic regression analysis was conducted to examine possible associations for knee OA with MetS and MetS parameters.… Show more

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Cited by 69 publications
(84 citation statements)
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“…Our finding regarding the metabolic syndrome in relation to knee OA is in accordance with a recent study of Han et al ,24 reporting no association between metabolic syndrome and knee OA. Another recent study, by Monira Hussain et al ,25 did report an association between metabolic syndrome and knee OA, adjusted for BMI.…”
Section: Discussionsupporting
confidence: 93%
See 1 more Smart Citation
“…Our finding regarding the metabolic syndrome in relation to knee OA is in accordance with a recent study of Han et al ,24 reporting no association between metabolic syndrome and knee OA. Another recent study, by Monira Hussain et al ,25 did report an association between metabolic syndrome and knee OA, adjusted for BMI.…”
Section: Discussionsupporting
confidence: 93%
“…Two recent studies on the metabolic syndrome, as surrogate for systemic processes, in relation to knee OA reported conflicting results. One observed an association between the metabolic syndrome and increased OA incidence even after adjustment for body mass index (BMI), whereas the other did not 24 25. So far, no studies examined knee OA in the presence of OA of non-weight-bearing joints as the hands, while this type of polyarticular OA might be particularly driven by systemic processes.…”
Section: Introductionmentioning
confidence: 99%
“…MetS is defined as the presence of any three out of five components: that is, abdominal obesity ≥102/88 cm (western, male/female) and ≥90/85 cm (eastern, male/female) [8, 15]; hypertriglyceridemia ≥150 mg/dL; low high density lipoprotein cholesterol (HDL-C) <40 mg/dL in men and <50 mg/dL in women; high blood pressure ≥130/85 mmHg or use of antihypertensive medication; or high fasting glucose ≥100 mg/dL or being under treatment for diabetes.…”
Section: Methodsmentioning
confidence: 99%
“…В его основе лежит концепция нарушения системной регу-ляции суставных тканей. Некоторые исследователи склонны рассматривать МетОА только как следствие избыточной нагрузки на опорные суставы вследствие ожирения [19]. Однако многие недавние исследования продемонстрировали, что адипокины, продуцируемые жировой тканью, гипергликемия, инсулинорезистент-ность и дислипидемия могут нарушать метаболизм суставных тканей, впрочем, как и других органов [1,4,8,10,21].…”
Section: ë³êàðþ ùî ïðàêòèêóº / To General Practitionerunclassified