Correlation of Antisperm Antibodies with Trace Elements in Seminal Fluid of Immunologic Infertile Men

Jewad, Abdulkareem M.; Alkhafji, Ehab Rasmi; Ali, Naael Hussein

doi:10.36295/asro.2019.22045

Cited by 2 publications

(2 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An immunological cause may be present in 5-15% of male infertility problems, including infections, cryptorchidism, primary testicular failure, testicular trauma, epididymitis, varicocele, idiopathic infertility, and epididymitis. As a result, males with primary or secondary infertility have ASA (Jewad et al, 2019). The presence of antisperm antibodies in serum is one of the potential immunologic causes of infertility.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation the level of antisperm antibodies, some cytokines and zinc for oligozoospermia, asthenozoospermia patients compared with normozoospermia

Ahmad

Al-Murshidi

2022

ijhs

View full text Add to dashboard Cite

Evaluation of the level of anti-sperm antibodies, some cytokines and zinc for oligozoospermia patients, asthenozoospermia patients and normozoospermia patients. Semen samples were collected from asthenozoospermic, oligozoospermic, and normozoospermic men who attended the fertility center. The collected samples of normozoospermia patients were (15), Asthenozoospermia patients were (15), and Oligozoospermia patients were (13). Seminal plasma for all study groups was evaluated for interleukin-1, interleukin-6, and zinc levels. The result showed there were statistically significant differences (p < 0.05) in sperm concentration, progressive motility, and liquefaction time in the asthenospermia and oligospermia groups compared with the normospermia group. This study found that antisperm antibody, interleukin 1, and interleukin 6 were higher in the oligozoospermia and asthenozoospermia groups than in the normozoospermia group. The levels of antisperm antibodies and interleukins increase, while zinc levels decrease in the seminal plasma of patients with oligospermia, as well as those with asthenospermia, compared to patients with normospermia.

show abstract

Section: Introductionmentioning

confidence: 99%

“…The presence of antisperm antibodies in serum is one of the potential immunologic causes of infertility. ASA is present in both primary and secondary infertile males (Jewad et al, 2019). Cytokines are a component of the male reproductive system's autocrine/paracrine network.…”

Section: Introductionmentioning

confidence: 99%

Evaluation the level of antisperm antibodies, some cytokines and zinc for oligozoospermia, asthenozoospermia patients compared with normozoospermia

Ahmad

Al-Murshidi

2022

ijhs

View full text Add to dashboard Cite

show abstract

Nickel and human sperm quality: a systematic review

Vinnikov,

Syurin

2024

BMC Public Health

View full text Add to dashboard Cite

Background Reproductive effects of chronic exposure to nickel (Ni), including sperm quality, have been a matter of debate given that published studies yielded contrasting results. We have, therefore, planned to systematically search and analyze medical literature with the aim to ascertain the association of exposure to nickel with the sperm quality in humans. Materials and methods We systematically searched Pubmed, Scopus and Embase for studies reporting the association of Ni with the sperm quality in humans with no time or language limits and used PRISMA to report the findings. The risk of bias was assessed using JBI critical appraisal checklist and SIGN tool. Because the reported effects were no coherent, meta-analysis was not possible. Results All included studies were observational and planned to test the effect of a group of trace elements, but not Ni alone. We identified and included 19 studies from 23 publications, published from 12 countries, which assessed sperm quality, sperm DNA damage and sperm metabolome. Ni was quantified in blood, semen plasma, spermatozoa and urine. Sixteen included cross-sectional studies were of acceptable quality, whereas three more case-control reports were of poor quality. Multivariate models were reported in only eight studies. Overall, studies were inconsistent in the direction of effect, when elevated Ni was not associated with the outcome (N = 8 studies), or some association was present (N = 11 studies). In the latter, 9 studies yielded elevated risk and 2 studies exhibited protective effect. Only one report was in an occupationally exposed population with some association with tail defects, but present in both welders and controls. Conclusions Existing evidence from the studies in humans is inconsistent and does not confirm a clear adverse effect of higher Ni concentrations in blood, urine or semen on the sperm quality. Robust methodology must be a key issue in the future studies. Studies with more powerful evidence, such as cohort or experimental reports are needed.

show abstract

Correlation of Antisperm Antibodies with Trace Elements in Seminal Fluid of Immunologic Infertile Men

Cited by 2 publications

References 7 publications

Evaluation the level of antisperm antibodies, some cytokines and zinc for oligozoospermia, asthenozoospermia patients compared with normozoospermia

Evaluation the level of antisperm antibodies, some cytokines and zinc for oligozoospermia, asthenozoospermia patients compared with normozoospermia

Nickel and human sperm quality: a systematic review

Contact Info

Product

Resources

About