Correlation of increased oxidative stress to body weight in disease-free post menopausal women

Evaluation of antioxidant activity of grapevine leaves extracts (Vitis labrusca) in liver of Wistar rats

“…CCl 4 -induced reduction may be attributed to the generation of the reactive specie H 2 O 2 , which is the product of the enzymatic reaction performed by SOD. According to Mittal and Kant (2009), with increased oxidative stress, SOD decreases due to irreversible inactivation by its product, H 2 O 2 (Mittal and Kant 2009). This reduction also increases when combined with the extracts, which may be attributed to the effect of the polyphenols that could be playing the role of the "SOD-like" enzyme acting as antioxidants (Calderón et al 2009).…”

Oxidative Stress in Obese Postmenopausal Women: An Additive Burden for Atherosclerosis

“…Women have unique risk factors for CAD [3,4] and postmenopausal women are at higher risk of developing CAD when compared to normal menstruating women [2,[5][6][7]. In general postmenopausal women are subjected to oxidative stress which is attributed to aging and other related factors [8]. Oxidative stress has known to play crucial role in many human diseases and atherosclerosis is one of them.…”

Nutritional habits and oxidative stress in postmenopausal age

“…3,5,6 It is associated with a significant change in the antioxidant gene expression, which in turn affects the circulating redox state. Estrogens act as regulators of the key antioxidant gene expression.…”

“…34,35 Postmenopausal hypoestrogenism also affects SOD activation, and the activity of this enzyme is decreased in peri-and postmenopausal women with cardiovascular diseases in comparison with the premenopausal stage. [4][5][6] Also, a diet rich in proatherogenic lipids (e.g., dietary cholesterol or saturated fatty acids) reveals the pro--oxidant effect and change in the SOD activity. 36 In this study, the SOD activity was positively correlated with the HDL fraction, which has a cardioprotective effect; however, it was inversely correlated with proatherogenic parameters such as TC --to -HDL and LDL -to -HDL ratios in both groups.…”

“…Moreover, obesity, as a component of metabolic syndrome, is frequently associated with a higher level of circulating low -density lipoproteins (LDLs), which are easily oxidized. [3][4][5][6] In lipid disorders, an enhanced synthesis of malondialdehyde (MDA) and advanced oxidation protein products (AOPPs) is observed; however, an intake of 3-hydroxy-3-methyl-using a 24 -hour recall during 7 days. 10 The results of the questionnaire were analyzed with both the quantitative and qualitative analyses of the subjects' daily diets 11 using computer databases for Microsoft Access 2000.…”